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Biomedical subjects

F Lemma

Publications and source records attributed to F Lemma.

47 records · Page 3Linked to original sources

[Treatment of single hepatic metastasis from surgically treated breast carcinoma. (Report of a clinical case and review of the literature)].

In the natural history of the breast cancer, the liver metastatic location represents a clear element of an advanced stage of the disease, because it is often accompanied to multiple locations in the same organ and/or in different organs and tissues. The finding into two years after the primary intervention, during the ordinary follow-up, of an insulated metastasis in the 3rd hepatic segment in a patient operated for breast carcinoma, and the following surgical treatment of the metastasis, have suggested us to draft this note. The finding of a single metastasis in the liver in patients operated for breast carcinoma imposes a revaluation of the stage of sickness to highlight the contemporary presence of subsequent distance metastatic location; the negativity of the instrumental investigations performed has triggered the question about the type of therapeutic treatment to do to the patient. The range of therapeutic hypothesis spaces from the ultrasound guided mini-invasive techniques (alcoholization, infusion of LAK cells, use of radio frequencies), to the chemotherapy, so general that local one, by means of super selective catheterization of the hepatic artery, up to the, finally, minus usual (in these cases) surgical therapy. In the patient observed we have chosen the surgical treatment, consisting of a segmentary resection, we haven't any complication, neither intra- nor post-operative, and the patient was discharged in 8th day. Our choice of the surgical approach has bean consequence of an attentive evaluation so of the clinical indicators of the patient (good general conditions, bulk of the injury and surgical treatableness) that of the biological parameters of the neoplasm. The results of our experience, in line with whet indicated from the other AA., encourage the choice of the surgical treatment of the insulated hepatic metastasis from breast carcinoma, with the awareness of the concept of "adjuvant" that it necessarily engages in such circumstances, and, however, after an accurate selection of the patients.

Aged↗

[A case of intestinal obstructions caused by a gossypiboma].

The Authors explain a case of intestinal obstruction due to a gossypiboma. They stress the great importance of the prevention in surgical operations (count of surgical towels, exploration of the surgical site) and the role of the differential diagnosis.

Aged↗

[Merkel cell tumor: a case report and literature review].

Merkel cell tumor (MCT) is extremely rare, being discovered so far about 400 cases in literature. It is classified among neuroendocrine tumors. We report a case of MCT in the subclavicular region in a 93 years old woman. We confirm the efficacy of radiotherapy associated with octreotide, which these tumours express specific receptors for.

Aged↗

[Etiopathogenic hypothesis on carcinoma of the gallbladder: our study].

The authors are interested in determining causes of gallbladder cancer (GBC). By this intention, they theorize a correlation between genetic modifications (which are responsible of malignant transformation of biliary epithelium) and some intestinal infections. From 1999 to 2004 they observed 15 GBC and all 15 gallbladder have been analyzed histologically and from microbiological aspect; by these means from 1999 till 2004 they have studied also 30 persons with colelithiasis. The authors noticed that bile of both groups contained, in three cases in the first and in 8 cases in the second, a germ named Escherichia Coli which normally lives in intestine, while in 10 operated gallbladders of the first group and 12 of the second there was a positive for k-ras. They are studying to confirm their theories.

Aged↗

[Treatment of skin neoplasms with polidocanol infiltrations. Our experience].

The authors try to explain the importance of day surgery today. They report their 5 years experience in treatment of face and neck skin neoplasms by injections of a sclerosant product as hydropolyethoxydodecan, in case of a difficult good esthetic result with surgery or other therapies because of patients general conditions, such as diabetic ones, or because of their viral nature. Then they affirm to have treated 350 benign and malign tumors with this method. All subjects presented a complete resolution of disease in few weeks and none between them controlled has actually complications or recruitment of neoplasm. They conclude by saying that this result is probably due to local ischemic reaction caused by the substance used.

Aged↗

[Minimal breast carcinoma (the authors' experience)].

The authors relate their experience about twenty-one cases of impalpable lesions of the breast come to their observation during the years 84-88. After expanding therapeutical tactics carried out by them, the promoters infer asserting that a wide diffusion of screening programmes allowed a more verifications of the minute lesions of the breast, addressing the surgeon towards operations more and more conservatives.

Adult↗

[Gynecomastia: diagnosis and therapy update].

The Authors report their experience in the management of gynaecomastia. Physiologic, pathologic and iatrogenic causes of the lesion, as well as possible interfering mechanisms, and diagnostic protocol are examined. When there is no spontaneous regression or when the precipitating factors are eliminated surgery is the therapeutical choice, also because it helps in resolving the related psychological problems affecting these patients.

Adolescent↗

[Sedation in endoscopic diagnosis: rationale of the use of specific benzodiazepine antagonists].

The aim of this study was to evaluate the best clinical use of Flumazenil, a specific antagonist of benzodiazepines, during endoscopic exams. Two-hundred patients were studied: 120 were treated with Flumazenil and 80 with placebo. The patients were prepared for the endoscopic exam with local anaesthesia and i.v. Diazepam administration. Controls performed at the end of the exam and at 5, 30, 120 e 240 minutes from the administration of Flumazenil and placebo, allowed to evaluate the state of awakeness, the level of conscience and the capacity of time-space orientation. Significantly statistical differences between the two groups were obtained at 5, 30 and 120 minutes after Flumazenil administration, while both groups had retrograde amnesia. The drug was well tolerated and there were no undesiderable side effects or reactions. The Authors therefore affirm that Flumazenil, in virtue of its competitive action toward benzodiazepine receptors, interrupts sedation with immediate awakening and improvement of the state of consciousness. Such drug, thus, permits the Day Hospital performance of endoscopic procedures which otherwise would require hospitalization, at the same time allowing the surgeon to use benzodiazepines at doses more adequate for surgical necessities.

Adult↗

[Clinical study of residual function and recurrence in patients undergoing partial thyroidectomy for euthyroid nodular goiter].

The different surgical options for the treatment of non toxic nodular goiter led the Authors to study the residual thyroid function following conservative surgery (subtotal thyroidectomy, lobectomy and enucleation). Follow-up showed an overall recurrence rate of 49%, with a higher rate after lobectomy and enucleation than after subtotal thyroidectomy. On the other hand, subclinical hypothyroidism was higher in patients who underwent subtotal thyroidectomy. No significative correlation was found between high plasmatic levels of TSH and recurrences.

Adult↗