Stewart's malignant centrofacial granuloma is a rare affection. The characteristic clinical features are extensive ulceronecrotic processes affecting the upper respiratory tract, these being always unilateral, with no lymph node adenopathy spread and no visceral dissemination (confirmed in all cases in which an autopsy was conducted). There are no specific biological changes that could supply objective confirmation of the affection. The histological appearance is that of a granuloma with non-specific inflammatory signs, but having a pseudo-malignant appearance in some cases which is difficult to interpret. The true etiopathogenic nature of the lesions remains obscure. The most admitted current hypothesis is that Stewart's malignant granuloma is an immune response, in a granulomatous mode, to an antigenic stimulation, the antigen being unknown.

Facial Neoplasms↗

PubMedDate not supplied

[Isolated otorhinolaryngologic manifestations disclosing amyotrophic lateral sclerosis].

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Aged↗

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[Intrapetrous vascular tumors. Difficulties in the clinical, arteriographic and anatomo-pathological diagnosis].

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Angiography↗

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[Solacy: its place in the treatment of refractory and recurrent diseases of the upper respiratory tract].

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Adolescent↗

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[Value and limitations of complementary studies in the sequelae of head injuries without any clinical symptoms. The otorhinolaryngologist's viewpoint].

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Audiometry↗

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[The role of salivary gland scintigraphy in ear, nose and throat surgery (author's transl)].

Scintigraphy of salivary glands might appear to be a relatively minor test in the study of the morphology of the salivary glands and especially tumours. However, with recent technical progress, it is an extremely useful test in th study of the function of the principal salivary glands. Changes in salivary secretion in certain severe facial paralyses could become an interesting prognostic test; on this subject, the simultaneous abnormalities in sub-maxillary and parotid salivary secretion in these cases of paralyses poses a physiological problem. The study of salivary junction is indispensable in the exploration of aptyalia (in particular in the Sjögren's syndrome), and in sialosis.

Adolescent↗