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Biomedical subjects

F Le Gall

Publications and source records attributed to F Le Gall.

At least 91 records · Page 5Linked to original sources

[The distribution of the tsetse fly (Diptera: Glossinidae) in the humid savanna zone (Central African Republic). Evaluation of prospective entomological techniques].

Two trapping methods were compared during a survey of the distribution of tsetse flies in the Mbororo cattle breeding area of the Central African Republic: (a) several traps dispersed throughout the riverine forest galleries and remaining only one day at each site: (b) one sentinel trap placed at the cattle drinking point and remaining for several days. The latter method was more reliable and is therefore recommended. The concentration of tsetse flies at the drinking points was negligible during the rainy season.

Animals↗

Objective determination of the bioavailability of dermocorticoids--influence of the formulation.

In order to quantify the intensity of skin blanching and thus predict the bioavailability of topical corticoids, a physical device allowing the measurement of light reflected from skin without any contact between the probe and the skin was used (Leveque et al., 1984). Three series of experiments were carried out: firstly, to assess the vasoconstrictor potency of four corticoids; secondly, to show the influence of the vehicle on the bioavailability of the same drug under various galenic forms, such as fatty ointments or water in oil (W/O) and oil in water (O/W) creams; thirdly, to determine the reservoir effects, if any, of some of these formulations. The results confirm previous findings about the potency of hydrocortisone acetate, triamcinolone 17-acetonide, betamethasone 17-valerate, diflucortolone valerate and clobetasol 17-propionate.

Administration, Topical↗

["Pericardial" friction rubs in pulmonary embolism (author's transl)].

In a series of sixty-five patients with pulmonary embolism, the main clinical feature was a systolic and diastolic friction rub in three cases. Such friction rubs are found in 1 to 5% of patients with pulmonary embolism. The characteristics of the rub are identical to those of pericardial friction rubs. According to some authors, a friction rub indicates massive pulmonary embolism. However, a friction rub may be found in less severe cases if embolization involves the paracardiac lobes or segments. The rub may be caused by one or the other of the following mechanisms. Severe pulmonary embolism or a free blood clot floating in the right atrium or ventricle may produce a sound resembling a friction rub. More often, a genuine pleuro-pericardial or pericardial friction rub originates in an inflammatory reaction to a contiguous pulmonary infarct. It is important to establish accurate diagnosis of pulmonary embolism in spite of a pericardial friction rub because of the therapeutic implications. Anticoagulant therapy in sufficient dosage must not be withheld in this situation.

Adult↗

[Rare etiology of hemiplegia with young adult: paradoxical embolism (author's transl)].

Paradoxical embolism is due to the passage of an embolic material from the deep veins of the lower extremities or pelvis, into the systemic circulation through an abnormal intracardiac communication. Only the angiographic and hemodynamic diagnosis practised on two young patients with a cerebral embolism, can explain the mechanism. The diagnosis is based on the arterial embolism, the venous thrombosis with or without pulmonary embolism, the abnormal communication favoring right-to-left shunting. The rising of right atrial pressures permits this shunting. This high pressure can result from a pulmonary embolism, a high blood pressue due to an effort, or an embolism that might coil up over the tricuspid valve.

Adult↗