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Biomedical subjects

F Lazorthes

Publications and source records attributed to F Lazorthes.

65 records · Page 4Linked to original sources

Comparison between oral and systemic antibiotics and their combined use for the prevention of complications in colorectal surgery.

Ninety patients were included in this prospective randomized trial. Each required electric colorectal surgery and was prepared for operation with oral preoperative antibiotic therapy, systemic peroperative therapy, or by a combination of both. The number of each type of septic postoperative complication and their total did not differ between the group treated by oral antibiotics prior to operation and the group treated peroperatively with systemic antibiotic therapy. The total number of septic complications (wall abscesses, fistulas, subdiaphragmatic abscesses, septicemia, peritonitis), however, was significantly less (P less than 0.05) in the group treated by both preoperative oral antibiotics and peroperative systemic antibiotic therapy (3.3 per cent) than in either groups treated only orally preoperatively (30 per cent) or by systemic antibiotic therapy during the operation (23 per cent). The combination of oral antibiotic therapy prior to operation and of systemic peroperative antibiotic therapy, therefore, presents the most effective prophylactic effectiveness.

Administration, Oral↗

[Inguinal hernia. The Shouldice parietal repair].

Parietal repair according to the Shouldice technique consists of a double line of sutures on each of three musculo-aponeurotic layers of the groin, i.e. successively: plicature of the transverse muscle and attachments; aponeuroplasty by back-to-back suture of the internal and external oblique muscles, and plicature of the aponeurosis of the external oblique muscle. Parietal repair of this kind is only possible after wide dissection of the inguinal region. It can be performed under local anaesthesia during a short hospitalization period. Normal activity is rapidly resumed, and in the experience of those who favour this technique, the recurrence rate is a mere 1%.

Abdominal Muscles↗

[Evaluation of systemic antibiotic preventive treatment in colorectal surgery].

A comparison was made of two methods of prophylactic antibiotic therapy against the septic complications of colonic and rectal surgery: --preoperative oral antibiotics associated with peroperative systemic antibiotics; --peroperative systemic antibiotics only, continued for 24 hours after surgery. Both types of antibiotic therapy were of short duration and were designed to cover aerobic and anaerobic organisms. Two groups of 30 patients were selected at random. They were homogeneous. The septic complication rate was 10% in the oral plus systemic and 24% in the systemic group. It is felt that the combination of oral and systemic antibiotics remains preferable, in particular bearing in mind the efficacy of oral metronidazole.

Anti-Bacterial Agents↗

[An accident related to a seat belt. Lymphocoele and extrinsic stenosis of the ureter in a transplant patient. Reparative surgery (author's transl)].

Trauma to a graft by a seat belt in a young adult, 18 months after transplantation. Drainage shortly after of a voluminous perirenal haematoma, abundant discharge of lymphorrhoea taking two months to resolve. Good recovery of the graft from both a radiological as well as biological standpoint. 4 years after the trauma, leucocytes in the urine associated with impairment of function of the graft. Discovery of a large hydronephrosis related to retro-peritoneal fibrosis. Ureterolysis with resection of the affected part of the ureter followed by anastomosis. Return to normal of renal function with disappearance of the hydronephrosis. Lymphocoele, a rare complication of renal transplantation, is discussed from three viewpoints: aetiopathology, diagnosis and treatment.

Accidents, Traffic↗