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Biomedical subjects

F Laurent

Publications and source records attributed to F Laurent.

At least 199 records · Page 11Linked to original sources
PubMed1985

[Solitary plasmocytoma of the mandible].

The authors present a case of solitary bony plasmocytoma of the mandibule, with local amyloid deposition. Diagnosis was made at extemporaneous pathological examination, then confirmed by the examination of the fixed surgical sample. Immunoenzymologically the proliferation proved to be monoclonal, with secretion of kappa light chain. The patient was treated by surgical curettage and homologous cancelous bone filling, followed by 5,500 rads of electrontherapy. He was then regularly controlled during 8 years and remained free from local recurrence. All investigations in search of dissemination (Kahler disease) remained negative.

Humans↗
PubMed1984

[Nephroblastoma with egg-shell peripheral calcifications. Apropos of 3 cases].

Three cases of nephroblastoma presented "egg-shell" peripheral calcifications of pseudocystic appearance of radiology. These peripheral lesions are compared with the more commonly reported central calcifications. Their pathology is unknown and they lack prognostic significance of any importance. As for all nephroblastomas the diagnosis is based on straight abdomen images, intravenous urography, ultrasound and computed tomography. Differential diagnosis is basically from renal adenocarcinoma in children, the latter often exhibiting similar calcifications, the distinction between the two types of tumor depending on age of onset. These calcified lesions are non-specific findings and various diagnoses are discussed.

Adenocarcinoma↗
PubMed1984

[Cardiac transplantation: noninvasive detection of rejection by echocardiography].

The main objective of follow-up of cardiac transplant patients is early recognition of acute rejection of the allogenic myocardium. Two patients followed up by the usual protocol also underwent routine M-mode and 2D echocardiography. The data was digitalized and memorized to allow systematic study of the pericardial and cardiac structures, and a comparison of their evolution. Acute rejection was associated with an increase in the acoustic density of the myocardium, especially of the interventricular septum, and an increase in myocardial mass as calculated from M-mode data; an increase of 5 p. 100 of this parameter with respect to an average reference value was judged to be significant. Comparisons were made with electrocardiographic data, especially with an index of voltage. The variability of this index which may be unrelated to rejection was apparent; in addition, there was an interval of about 5 days between the echocardiographic changes and the recording of significant reductions of the electrocardiographic index. Previously reported histological changes explain the precocity and reliability of the echocardiographic results obtained by a non-invasive and reproducible method.

Adult↗
PubMed1984

[Congenital toxoplasmosis and transfontanelle brain echography. Apropos of 8 cases observed in newborn infants and infants].

The undeniable value of brain ultrasound imaging in the detection of ventricular dilatation is emphasized, and a classification of intracranial calcifications proposed: hyperechogenic, nodular and irregular large images and those without a posterior shadow cone. Comparison between simple films and particularly computed tomography images was conducted in the cases studied.

Brain Diseases↗
PubMed1984

[Stenosis of the external ear canal due to meniscus intrusion].

The authors, maxillo-facial and ENT surgeons, present a unique case of hearing impairment due to external meatus obstruction, occurring at mandibular occlusion. On the contrary, a dimple of the anterior wall was noted at opening of the mouth, with recovery of the hearing impairment. The external meatus returned to normal after resection of posterior mandibular disc protrusion, combined with interposition of a cartilaginous homograft. Etiology of this condition is unknown and a search through the literature revealed no similar observation.

Cartilage, Articular↗
PubMed1984

[Primary neuroblastoma of the mandible. Apropos of a case].

Concerning an observation of mandibular neuroblastoma, the problem of a probable primary localization of this neurocristopathy is raised on the face level. Actually, classically speaking, it can only be a question of metastasis revealing a tumor initially located in the abdomen, the thorax, or more rarely in the pelvis or the neck. However, the evolution of the lesion under treatment leading to complete cure within three years denies the secondary nature of the process. Related to the three other cases in the world that have so far been published, our observation enables to assert the reality of the primary development of a neuroblastoma on the mandibular level. The coherent reasoning is founded on the role of neural crests in facial embryogenesis whose vitiation offers a logical explanation to this exceptional phenomenon.

Child↗
PubMed1984

[Computed x-ray tomography of abdominal lipoma and liposarcoma in adults. Apropos of 9 cases].

CT scans were performed in 9 patients with fatty tumors of the abdomen: 2 lipomas and 7 liposarcoma. Of primary retroperitoneal origin, five tumors had extended intraperitoneally. Scanning images typical for each type of tumor are described: lipomas are very hypodense and well circumscribed, with thin intratumoral septa; liposarcomas are less hypodense and contain thick septa which may coalesce and form large nodules. Scanner imaging provides precise data on tumor extension and allows early detection of recurrences of these fatty tumors.

Abdominal Neoplasms↗
PubMed1983

[Factors altering allantoin excretion by sheep and goats].

We have studied the factors of variation of the urinary allantoin excretion with sheep billy goats and goats during digestibility trials. The urinary excretion of nitrogen allantoin (Nal) is highly correlated with the intake of digestible organic matter (DOM) and soluble nitrogen (Ns) for the sheeps billy goats and goats. By multiple regression we have estimated the daily endogenous excretion of Nal at 160 mg (goats) and 60 mg (sheeps and billy goats) respectively 8.5 and 2.6 mg/kg W0.75. The differences observed between sheeps and billy goats (Nal = 27.3 +/- 11.3 and 32.2 +/- 9.4 mg/kg W0.75) agree with the differences observed in the DOM and Ns intakes. The dairy goats eat more than the billy goats (69.5 against 52.0 DOM/kg W0.75 and 412 against 315 mg Ns/kg W0.75) but they excrete less Nal (36.3 mg against 42.3/kg W0.75). During the first two weeks of lactation the goats with negative N balance excrete more Nal than the goats with positive N balance (78 mg Nal against 57 mg/100 g DOM). Although large variations of DOM and Ns, the amount of Nal excreted before and after kidding doesn't vary. In these last conditions the general relation between Nal and intake of DOM and Ns no longer holds. Since the disponible energy (MOD) and soluble nitrogen intake supplies for the rumen microorganisms influence the amount of synthetised microbials protein (and so the amount of nucleic acids entering the duodenum) our regressions confirm the assumption that the excretion of Nal is related with the nucleic acids metabolism. However when Nal is utilised as an index of the nucleic acids catabolism, the factors that are able to create the variations either in the endogenous production of allantoin (uterine involution, bodily mobilisation, foetus growth, mammary gland development) or in the nucleic acids valorization must be taken into account.

Allantoin↗
PubMed1982

[High-risk groups in pre-school children. Cluster analysis (author's transl)].

A 3 years supervision of 415 pre-school children was undertaken in Paris from 1974 to 1977. Four epidemiological sets of questions provided information on the familial and social situation as well as on the physical and psychological development of the child at 3, 9, 18 and 36 months of age. A cluster analysis was applied to the behavior and health variables in the 3 year-old child and 3 different groups were identified. Most children (69%) belong to the first group, characterized by the absence of difficulties or the presence of a few minor symptoms, 10% of the children belong to the third group, a "high risk group" because of their high frequency of symptoms. Half-way between these 2 groups, a "low-risk group" (21%) was identified. The reliability of this analysis was further supported by the study of the families (especially their social and economic status and the parents' mental health). This study also revealed the early onset of the symptoms in high risk children.

Behavior↗
PubMed1982

[Congenital esophagotracheal fistulas in adults. Apropos of 2 cases].

Repeated bronchopneumopathies are the principal manifestation of congenital esophagotracheal fistulae detected at a late stage. Diagnosis is suggested by air distention of the esophagus on the thoracic image. Esophageal barium swallow examination in the standing position is usually negative: esophageal transit is too rapid, the diameter of the fistula is too small, and its ascending pathway does not allow filling by the contrast medium. Examinations should be conducted in precubitus, after the passage of an esophageal sound, employing barium sulphate as the contrast medium, and with a horizontal beam and profile projection. Kinetic exploration, employing ampliphotography is necessary. The fistula pathway is seen as a thin opaque line, oblique from above forwards, and pushing from the anterior surface of the esophagus to the posterior surface of the trachea. There is associated filling of the tracheobronchial tract.

Adult↗
PubMed1981

Effect of insulin on glucagon secretion mediated via glucose metabolism of pancreatic A cells in ducks.

A possible action of insulin via glucose metabolism on the pancreatic A cell response to glucose, was studied in ducks. 2-Deoxyglucose, a nonmetabolizable analogue of glucose was used. In normal ducks, the hyperglycaemia induced by 2-deoxyglucose (IV: 0.5 g/kg) resulted in hyperglucagonaemia, while the same degree of hyperglycaemia, induced by glucose infusion (IV injection 25 mg/kg, and infusion 5 mg/kg/min) immediately suppressed glucagon secretion. In diabetic ducks, two days after subtotal pancreatectomy, glucose responsiveness of the A cell was abolished, but could be restored by insulin treatment before (IM 0.2 U/kg insulin + 8 micrograms/kg glucagon every 6 h) and during (IV 3.6 mU/kg + infusion 0.9 mU/kg/min) the glucose test (IV: 0.5 g/kg). The normal response of the A cell to glucose was not observed in diabetic insulin-treated ducks after the administration of 2-deoxyglucose (IV: 0.5 g/kg). These data suggest an inhibitory effect of the metabolism of glucose on the release of glucagon. In addition, the action of insulin on the A cell may be mediated by its effect on glucose metabolism within the A cell.

Animals↗
PubMed1980

Surgical transposition of the atria: A new procedure for repairing transposition of the great vessels.

The proposed procedure consists of interchanging the positions of the atria by means of an incision used in heart transplantation. After frontal sectioning of the atrial body, the heart is turned up on its pedicle, the interatrial septum is divided in its posterior part, and the vena cavae are extensively freed from their mediastinal and diaphragmatic attachments. The posterior parts of the atria can then be transposed: the right atrium and vena cava are repositioned to the left of the left atrium, and a new septum is constructed by joining the external atrial walls. The heart can then be replaced and the walls of the transposed atria repaired by edge-to-edge sutures. Cadaver experiments have indicated that this procedure is applicable in infants and young people. Casts and radiologic examinations have shown no strictures in the vena cavae, and the possibility of postoperative arrhythmias has been evaluated by means of electrocardiographic studies in dogs surviving for long periods after heart autotransplantation.

Journal Article↗
PubMed1980

[Echocardiography in the evaluation of constrictive pericarditis. 25 cases].

Twenty five patients with constrictive pericarditis underwent cross-sectional and M-mode echocardiography before pericardectomy. The numerical data were compared with those in thirty healthy subjects. The various parameters noted regarding the left cavities were as follows: --The presence of a pericardial detachment which may sometimes be quite large (more than 10 mm in 6 cases); the degree of parallelism of the pericardial membranes in systole, which is all the less maintained as the detachment is severe. --The increase in size of the right ventricle and decrease of the left, with p less than 0.001 in both cases. --The absence of posterior motion of the left side of the septum in systole in 22 cases, followed by a sudden posterior displacement during the rapid filling stage, after which there is virtually no motion until the end of diastole. --The presence at the level of the posterior wall of a so-called slow filling slope, which is smaller (1.9 +/- 1.5 mm/s) than in the normal subject (p less than 0.001). --A change in left ventricular endocavitary diameter variations, which results from the two previous findings. The tracings thus show the compliance disorder with a very steep rapid filling slope and a plateau during the slow filling stage. --Finally the changes in mitral kinetics involving an earlier (p less than 0.001) and lower (p less than 0.001) F point than in the control series and on the other hand an larger E wave, sometimes forming a summation with A wave in sinus rhythm and a false A wave in atrial fibrillation. We think this type of motion is due to the disturbances in the two mechanisms (recirculation, breaking of a jet) which in physiological conditions seem to combine to chose the mitral valve at point F and account for the valve position in mid-diastole.

Adolescent↗