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Biomedical subjects

F Lancastre

Publications and source records attributed to F Lancastre.

At least 19 recordsLinked to original sources
PubMed1987

[Comparative study of the human basophil degranulation test and total and specific IgE levels in schistosomiasis. 54 cases].

In 54 patients (45 Africans and 9 West-Indians) we searched schistosomiasis and the presence of immunoglobulins E by different tests (total immunoglobulin E levels, measurement of specific IgE, human basophil degranulation test). In patients with an excretion of living eggs we observed 91.6% of positive responses for the II. B. D. T. and 100% for the specific IgE. In cases only identified by examination of rectal mucosa biopsy specimens showing apparently living eggs, we observed 75% and 87.5% of positive responses for the same tests. But in both categories of patients, the parasitological examination is the most important. Moreover the authors observed "false-positive" and "false negative" tests compared with the parasitological results and between the tests. It suggests that the best use of these is in case of very probable schistosomiasis without positive parasitological results.

Africa↗
PubMed1987

[Significance of the presence of Candida sp. in bronchopulmonary secretions. Contribution of pulmonary biopsy].

Candida SP is often found in broncho-pulmonary secretions (expectorations, bronchial aspirations, bronchiolo-alveolar lavage...); however, its presence even in massive amounts, is difficult to interpret. Is it a sign of broncho-pulmonary candidosis or mouth-pharynx contamination? The different clinical and biological elements, in particular immunology in immunodepressed patients, bring little information. In this article, we present the retrospective study of 18 patients hospitalized in Pneumology Department of Tenon Hospital for severe extensive pneumopathy of unexplained origin. In these patients, for the most part immunodepressed, Candida sp was found in large amounts in at least a sample (expectorations [5] and/or bronchial aspirations [4] and/or bronchiolo-alveolar lavage [12]. No lesion suggestive of candidiasis was found during bronchial endoscopy carried out for these different samples. In pulmonary biopsy with diagnostic in view, these yeasts were found only in one patient. In this patient, as C. tropicalis was associated with Pneumocystis carinii and Cryptococcus neoformans, it was difficult to know the respective part of each of these agents in pulmonary symptomatology. In the other 17 cases, the direct examination and cultures were negative. The presence of Candida sp in the different broncho pulmonary secretions is not synonymous of bronchopulmonary candidiasis; likely it is, in most cases, a sign of contamination of mouth-pharynx origin.

Adolescent↗
PubMed1986

[Toxoplasma gondii pneumopathy in a patient with the acquired immunodeficiency syndrome: demonstration of the parasite by bronchioloalveolar lavage].

Toxoplasmosis is an infection frequently observed in patients with acquired immunodeficiency syndrome. Its first manifestations usually are cerebromeningal symptoms, but others may occur. A pulmonary lesion is sometimes present; it is discovered at post-mortem examination in most cases. The authors report a case of pulmonary toxoplasmosis diagnosed by bronchoalveolar lavage (BAL). Three points are emphasized: toxoplasmosis of the lung may produce an interstitial pneumonia similar to that of pneumocystosis; diagnosis can be made non-invasively by BAL, and provided an appropriate treatment is administered, the outcome may be favourable.

Acquired Immunodeficiency Syndrome↗
PubMed1984

[Experimental schistosomiasis III. Observations on the infestation of Biomphalaria glabrata by a miracidium of Schistosoma mansoni].

380 B. glabrata infected with 1 miracidium of S. mansoni produced 87 positive snails (22,9%), 38 of which sending out male cercariae and 49 female cercariae. The snails belonged to 3 experimental series kept at 27 degrees and 24 degrees C for 15 weeks under continuous lighting. There was no difference between the proportions of both sexes. The survival of the positive snails was favoured by the male sex. The shedding of female cercariae was greater than shedding of male. During those 15 weeks, the cercarial shedding of both sexes showed large and recurring changes. A certain correlation seems to exist between the sex of cercariae, the abundance and the frequency of cercarial shedding, and the longevity of the parasitized snails. All those factors could take a part in the epidemiology of the schistosomiasis.

Animals↗
PubMed1979

[Cutaneous, subcutaneous, and lymph node cryptoccosis in a patient with sarcoidosis (author's transl)].

An Algerien patient aged 31 years with a histologically confirmed mediastinopulmonary sarcoidosis had a persistent stable miliary pulmonary x-ray image after cortisone therapy. Eighteen months after stopping the corticotherapy, he developed cryptococcosis which was mainly cutaneous, but associated with subcutaneous abscesses and peripheral adenopathy, and without lesions in the viscera or deep nodes. Cryptococcus antigens were present in the serum and there was a humoral and cellular immunity reaction towards the cryptococcus. Recovery occurred after amphotericin B and 5-fluorocytosine.

Adult↗