Biomedical subjects

F L Ruben

Publications and source records attributed to F L Ruben.

75 records · Page 5Linked to original sources

PubMedDate not supplied

Factors associated with acquisition of Pseudomonas aeruginosa resistant to gentamicin.

Concern over the increased occurrence of Pseudomonas aeruginosa resistant to gentamicin colonizing and/or causing disease in patients prompted our review of the years 1974 and 1975 for all P aeruginosa isolates, both gentamicin-resistant and gentamicin-sensitive. In this period, 39 patients had gentamicin-resistant P aeruginosa recovered from clinical specimens while 683 patients had gentamicin-sensitive strains. Compared to both matched and/or randomly selected controls with gentamicin-sensitive infections, patients with gentamicin-resistant infections had a higher incidence of (1) prior antibiotic therapy (p less than 0.01), (2) prior therapy with gentamicin (p less than 0.005), and (3) exposure to multiple antibiotics.

Adult↗

PubMedDate not supplied

Epidemiology of accidental needle-puncture wounds in hospital workers.

All employees, including physicians, of a 450 bed hospital were monitored for puncture wounds from contaminated needles over a four-year period. Five hundred seventy-nine incidents were reported. Nurses were involved in 66% of instances, housekeeping 16%, laboratory workers 10%, physicians 4% and x-ray technicians 4%. Many puncture wounds were avoidable, suggesting the need for ongoing employee education. In 67% of the injuries blood from the patient in whom the needle had been used was tested for HBsAg; 1% of those tested were positive. In such instances, employees were given immune globulin. These data indicate that needle puncture wounds are a frequent problem for hospital workers, and carry a risk for transmitting hepatitis B. Efforts to prevent such injuries are needed.

Accidents, Occupational↗

PubMedDate not supplied

Development and multicenter evaluation of Multistation Clinical Teaching Scenarios on immunization: the ATPM-CDC Teaching Immunization for Medical Education (TIME) Project.

INTRODUCTION: The objective of this project was to develop and evaluate case-based immunization education materials that use a new teaching method called Multistation Clinical Teaching Scenarios (MCTS) for use in medical school clerkships and primary care residencies. METHODS: A multidisciplinary team developed objectives, abstracted clinical cases, and created MCTS modules, which use contextual learning, problem solving, and small-group interaction. RESULTS: Mean scores increased from the 10-item pretest to the posttest by 3.2 (95% confidence interval [CI] of 2.8 to 3.6) items for measles, 3.8 (CI = 3.4 to 4.1) for influenza, and 1.8 (CI = 1.4 to 2.1) for hepatitis B (P < .01 for each). To evaluate the materials, we administered questionnaires and conducted focus groups. Most (99%) of the students and residents rated the materials highly, as did most (89%) facilitators. CONCLUSIONS: This new method has been widely tested, increases content mastery, and is well received.

Clinical Clerkship↗