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Biomedical subjects

F L Cohen

Publications and source records attributed to F L Cohen.

At least 37 records · Page 2Linked to original sources

Sex chromosome variations in school-age children.

Current evidence suggests that some school-age children are born with a sex chromosome variation. Large chromosome surveys of newborns indicate that 0.5% to 0.6% have chromosome errors, with sex chromosome variations accounting for 35% of them. The four most frequently occurring sex chromosome variations are Turner Syndrome (45,X), Klinefelter Syndrome (47,XXY), Polysomy X or Triple X (47,XXX), and Polysomy Y or XYY (47,XYY). Though many individuals with sex chromosome variations can live functionally normal lives, others may experience developmental, physical, psychological, behavioral, and learning impairments. New information has dispelled myths and biases previously associated with these disorders. By becoming knowledgeable about sex chromosome variations and their effects upon children, school health personnel can assist affected children, their families, and teachers.

Adolescent↗

Klinefelter syndrome.

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Adaptation, Psychological↗

Fibrous mass complicating epidural morphine infusion.

The benefits of continuous epidural morphine infusion using an implanted pump delivery system to control intractable cancer pain have recently been described. Most articles on this subject relate to dosage, technique, degree of pain relief, and tolerance. There are some anticipated complications of the treatment related to the surgical implantation of the system and drug toxicity. We present a complication presumably related to the epidural catheter. A fibrous reaction that developed around the catheter tip progressed into a mass. This caused a significant displacement of the spinal cord with the development of long tract symptoms. Identification of this abnormality using myelography and computed tomography led to prompt surgical decompression resulting in improvement of the patient's condition.

Aged↗

Conus medullaris syndrome following multiple intrathecal corticosteroid injections.

Few serious complications have been associated with the intrathecal administration of corticosteroids in the treatment of lumbar radiculopathy. This case of conus medullaris syndrome, which occurred coincident with multiple intrathecal steroid injections, suggests a more cautious approach to the treatment of benign disease by this method.

Adult↗

Genetic knowledge possessed by American nurses and nursing students.

As diseases of genetic origin have increased their impact on society's health, nursing's role has also increased. Nurses may not be referring those needing it for genetic counselling or prenatal diagnosis and may be inadvertently giving patients erroneous information based on lack of knowledge. A questionnaire was used to examine the overall adequacy and specific knowledge in the more commonly encountered genetic disorders such as sickle cell disease, Rh disease and Down's syndrome. It also included interpretation of risk and basic knowledge. The sample consisted of 366 senior nursing students and 114 practising nurses. Student programme type was consistently related to score. Age was also important in the degree of knowledge manifested. Only 19 (4.2%) of the respondents demonstrated over-all adequate knowledge. These results indicate a need to raise the consciousness and knowledge of nurses about human genetic disorders before serious repercussions result from inappropriate and inadequate counselling, health teaching and referrals.

Adult↗

Carotid sinus syndrome. Report of five cases and review of the literature.

Five cases of carotid sinus syndrome are presented. The syndrome is defined by spontaneous attacks of dizziness and fainting which can be reproduced by graded pressure on one carotid sinus. Three forms of the clinical syndrome, cardioinhibitory, vasodepressor, and cerebral, are discussed. The hyperactive carotid sinsu reflex, in which there is ventricular asystole lasting at least 3 seconds or a decrease of more than 50 mm Hg in systolic and diastolic blood pressure, should be differentiated from this syndrome. Treatment modalities include reassurance, drugs, radiotherapy, cardiac pacemakers, and surgical approaches. Carotid sinus syndrome should be considered in the differential diagnosis of unexplained syncope, arteriovenous block, or inappropriate sinus bradycardia.

Aged↗

Needs assessment of caregivers of people with HIV/AIDS.

This descriptive study assessed 34 caregivers of people with HIV/AIDS to learn their perceived needs, concerns, and use of services. Results indicated the most common health problems of the care recipient were fatigue and weight loss; care recipients needed help with climbing stairs, walking, and bathing; caregivers helped with the household chores, transportation, and companionship; caregivers were concerned about coping with loss and responsibilities; caregivers had help from family, case manager, and neighbor; caregivers wanted help such as a companion and counseling. Discussion relates to the implications of the study for health care professionals.

Adaptation, Psychological↗

Neural tube defects: epidemiology, detection, and prevention.

Neural tube defects are common congenital malformations of the central nervous system and include anencephaly, spina bifida, and encephalocele. Prenatal detection by amniotic fluid analysis of alpha-fetoprotein is possible in those women known to be at high risk for neural tube defects. Maternal serum screening for increased alpha-fetoprotein levels is now available nationally and has the potential to identify women who otherwise would not be known to be at risk. The epidemiology, detection, screening, and prevention of neural tube defects are discussed, and an explanation of alpha-fetoprotein and its use in screening is offered.

Acetylcholinesterase↗