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Biomedical subjects

F Kubli

Publications and source records attributed to F Kubli.

204 records · Page 12Linked to original sources
PubMedDate not supplied

[Significance of rheobase determination in detection of threatened premature labor].

In a prospective study of 176 pregnant patients it could be proved that the rheobase measurement during the whole course of pregnancy plays a significant role in recognizing the danger of premature labour. Taking a pathological limit from a number of rheobase determinations at a level of 3,4 mA, we had a sensitivity of 81% and a specificity of 50% in forecasting a premature delivery. The rheobase levels did not correlate significantly with the pelvic score (Bishop) and no correlation was found with the number of contractions measured tocometrically, nevertheless there was a correlation with the number of painful contractions between the 26th and 32nd week of gestation. Furthermore, we were able to certify the influence of psychic factors on the rheobase levels. As a result of our tests we consider the rheobase determination as being an independent, valid method for indicating premature labour. For this reason we included this procedure in our screening programme for recognition of threatened prematurity (Kubli u. Arabin, 1984).

Arousal↗
PubMedDate not supplied

[Puerperal uterine inversion].

Inversion of the uterus is a rare but dangerous postpartal complication. Morbidity and Mortality depend to a significant degree on early diagnosis and treatment. When the condition is detected early manual reposition and simultaneous shock therapy, which are usually possible, are of prime importance. Antibiotic prophylaxis should always be instituted in order to prevent any upward spread of infection. With appropriate obstetric management subsequent births can be uncomplicated, as in the case described by the authors.

Adult↗
PubMedDate not supplied

[Pathologic antepartal CTG as a prognostic factor for further development of the child].

A comparison was made between 123 infants with pathologic antepartal cardiotocograms (CTG) during late pregnancy and a corresponding control group of matched individuals with regard to obstetric and neonatal data as well as the subsequent neuromotor development of the infants. The group with pathologic antepartal CTGs contained 14 children with subsequent neuromotor abnormalities (one irreversible spastic diplegia, 13 reversible neuromotor disturbances) as compared to six cases of reversible neuromotor disturbances in the control group with normal antepartal CTGs. When compared to the control group, the group with pathologic antepartal CTGs manifested a significantly higher rate of pathologic intrapartum CTGs, as well as a higher number of clearly depressed neonates and of serious and slight cases of acidosis in the umbilical artery. In cases of neuromotor disturbances and pathologic antepartal CTG, complicated course of pregnancy (toxemia of pregnancy), premature births before the 37th week of pregnancy, and children with a low (less than 2,500 g) and very low (less than 1,500 g) initial weight are all to be found more frequently. There is, moreover, a clear connection between the degree of seriousness of antepartal CTG pathology and the subsequent occurrence of neuromotor abnormalities. The clinical consequences of the results described here include the early use of the antepartal cardiotocogram in cases of complications during pregnancy involving hypoxia (such as toxemia of pregnancy, premature labor, suspected intrauterine retardation of growth), as well as an increase in the frequency of CTG examinations, even to the point of continuous external cardiotocographic observation and, if other gestational complications involving hypoxia, especially the threat of premature birth, arise, the generous use of primary cesarean section.

Brain Damage, Chronic↗
PubMedDate not supplied

[Enzymatic determination of lecithin concentration in the amniotic fluid for antepartal determination of fetal lung maturity].

An enzymatic method of determining the lecithin concentration in the amniotic fluid is compared with the present standard method of antepartal determination of fetal lung maturity, i.e., determination of the lecithin-sphingomyelin (L/S) ratio. A total of 320 amniotic fluid samples, of which 154 were obtained within the 72 hours preceding birth, were studied by both methods. Simultaneously with the rise in the L/S ratio in the amniotic fluid there is a rise in the enzymatically determined lecithin concentration in the last quarter of pregnancy. The critical threshold value for RDS risk of 2 for the L/S ratio corresponds to a threshold value of 5 mg/100 ml amniotic fluid for the enzymatically analyzed lecithin concentration. Established lung maturity can be demonstrated with the same degree of confidence as by using the L/S ratio. The specificity of the both methods is 91%. It is at least as easily possible to predict the likelihood of respiratory distress syndrome by determining the enzymatic lecithin concentration (11 out of 15 cases) as by means of the L/S ratio (9 out of 15). In order to improve the sensitivity (L/S ratio 60%, enzymatic lecithin determination 73%) it would be necessary to perform an additional analysis-e.g., of phosphatidylglycerol-in the amniotic fluid.

Amniocentesis↗
PubMedDate not supplied

[Fetal arrhythmia].

Our present knowledge of fetal arrhythmias is described with reference to the literature and to the authors' personal experience. Most types of arrhythmia are harmless. Fetal tachyarrhythmias are of clinical importance, because of the danger of fetal cardiac insufficiency, and atrioventricular blocks because they are closely associated with infantile heart defects and maternal collagen disease. Problems of diagnosis and management are discussed.

Arrhythmias, Cardiac↗