Biomedical subjects

F Kotlarek

Publications and source records attributed to F Kotlarek.

41 records · Page 3Linked to original sources

PubMedDate not supplied

Orbital venous congestion in childhood. Diagnostic and therapeutical implications.

A case study of 2 patients with venous congestion of the orbit due to different etiologies is presented. Both the children demonstrated orbital pain, proptosis, chemosis and conjunctival injection. In one case early diagnosis left to complete recovery by conservative treatment in a patient with a pyogenic cavernous sinus thrombosis. In the other case a traumatic carotid sinus cavernous fistula could be treated successfully using transvasculary navigated detachable balloons.

Arteriovenous Fistula↗

PubMedDate not supplied

[How effective is the treatment schedule in children with infantile spasms?].

A fatal incident during combined anticonvulsive therapy with ACTH and Dexamethason prompted us to reevaluate our treatment results in 19 children suffering from infantile spasms. We followed Doose's recommendation using Clonazepam as a means of first choice. Failing that, than Dexamethason and Primidone was used. A combination of ACTH, Dexamethason and Primidone was administered to patients failing both treatment courses. Our results question the necessity, the tolerance limit and the efficacy of this treatment schedule. Therefore we propose a prospective multicentric study to reinvestigate the therapeutic guideliness for infantile spasms.

Adrenocorticotropic Hormone↗

PubMedDate not supplied

[The value of computer tomographic examination in children with congenital tetra- and diplegia].

31 children suffering from congenital spastic di- or quadriplegia, born between 1963-1976, were re-examined neurologically and admitted to CT. The mental level was obtained by noting the educational placement of the child. 14 patients showed normal CT patterns. In 17 patients a volume loss of the cerebral white matter with ventricular enlargement was present, but there were no local cortical defects. From similar changes on the ventricles in CT four different patterns can be ascertained. Belonging to one of these CT patterns permits no statement about the neurological and mental defect in an individual case. But massive ventricular enlargements e vacuo go hand in hand with serious neurological and mental defects.

Cerebral Palsy↗

PubMedDate not supplied

[Cerebral vein and sinus thrombosis--an important cause of benign intracranial pressure increase in childhood].

The syndrome of raised intracranial pressure without any space-occupying lesion (pseudotumor cerebri) is still of unknown etiology. To some degree, secondary causes can be found. With respect to the therapeutical possibilities, a clinically important cause is the thrombosis of a major cerebral sinus. In children it is sometimes associated with otitis media. However, clinical signs of mastoiditis can be missed because of previous antibiotic treatment. We observed 11 children with pseudotumor cerebri. Four children suffered from an occlusion of a lateral major sinus after otitis media. The treatment with heparin in the acute stage and later on with acetylsalicylic-acid led to complete recovery. Our results suggest that the thrombosis of a major cerebral sinus induced by an otitis media is a frequent cause of pseudotumor cerebri in children and should be excluded by MRI or angiography in any doubtful case. In contrast to the treatment of adults, long term anticoagulation is not necessary.

Adolescent↗

PubMedDate not supplied

[Neonatal, neurologic and psychosocial findings in higher order multiple births. Follow-up for 3 to 10 years].

We examined the outcome of 9 triplet, 3 quadruplet, 1 quintuplet and 1 sixtuplet pregnancies delivered between 1979-1989 at the perinatal center of the RWTH Aachen. The course of pregnancy and neonatal period were retrospectively analysed. The follow-up program covered at least 3, up to a maximum of 10 years. 12 families could be interviewed concerning psychosocial effects. The neonatal mortality was 4%. Neonatal morbidity; hyaline membrane disease (n = 18), intraventricular hemorrhage (n = 9), pneumothorax (n = 7), patent ductus arteriosus (n = 7), bronchopulmonary dysplasia (n = 8). At the age of 2 years 63% of the children were considered to be normal on developmental assessment, 17% showed mild, 20% severe developmental delay. With 3 to 10 years 83% were normal, 17% severely handicapped. In total 20% of the children died or showed severe handicap. Higher order multiple pregnancies make great demands on the perinatal medicine and lead in spite of an improved prognosis to a remaining burden for the children and their parents.

Brain Damage, Chronic↗