Biomedical subjects

F Konrad

Publications and source records attributed to F Konrad.

42 records · Page 3Linked to original sources

PubMed1988

[Alarms of medical-technical equipment in the surgical intensive care unit. A prospective study].

To test the need for a graded system of alarms on ICU we examined this aspect of present management by recording the number of devices and alarm-releasing facilities, the interpretation of alarms and type of response of the nursing staff. The data were recorded on multiphase basis at the operative ICU of a university hospital. The mean number of devices per patient was 4.3 and per room 11.5. The mean interval between 2 alarms was 5 min 30 s. In more than 50 per cent the first reaction of the staff was alarm-related. We conclude that the number of alarm signals should be reduced and unique signals used for each group of medical devices.

Equipment Failure↗

PubMed1988

[Does directed bronchoscopic bronchial cleansing have an advantage over conventional suctioning? A prospective study of hemodynamics, gas exchange and suction-induced mucosal lesions in long-term ventilated patients].

Hypoxic complications and epithelial damage to the trachea and bronchi during conventional blind suctioning have been described in the literature. Fiberoptic suctioning and examination of the trachea of each long-term ventilator patient as a routine method has been recommended in recent studies. We investigated the effect of a conventional tracheal suction technique compared to precise fiberbronchoscopic suction on cardiocirculatory function and gas exchange in mechanically ventilated patients. METHOD. In 40 long-term ventilator patients tracheobronchial toilet was performed either conventionally (group I; n = 20; 15 s of endotracheal suction with no mechanical ventilation during suctioning) or bronchoscopically (group II; n = 20; bronchoscope Olympus 1 T 10; mechanical ventilation during suctioning). Measurements were performed before, immediately after, and 1, 2, 5, and 15 min after suctioning. FIO2 was not changed before or after suctioning. In 12 long-term ventilator patients (greater than or equal to 8 days) we looked for tracheal mucosal lesions produced by conventional suctioning. RESULTS. There was no effect on cardiocirculatory function in either group (Figs. 1 and 2), but we found a decrease in arterial PO2 after suctioning in all patients (group I from 99 +/- 25 to 81 +/- 19 mmHg, group II from 104 +/- 23 to 80 +/- 17 mmHg [Fig. 3]). The time needed to re-establish the initial PaO2 after suctioning was significantly different in both groups. Whereas the PaO2 returned to the initial value within 2 min after conventional suctioning, we found a decrease in PaO2 in the bronchoscopic group even after 15 min.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

PubMed1987

[ARDS following amniotic fluid embolism. Case report of successful long-term intensive therapy].

A case of severe ARDS following amniotic fluid embolism is described. During the 15 month period of I.C.U. treatment a number of respiratory complications had to be overcome. Chronic hypercapnia led to changes of bone and soft tissue composition. The patient was discharged home with a marked restriction of pulmonary function. Respiratory infections continue to occur.

Adult↗

PubMed1986

[Behavior of insulin, glucagon, cortisol and thyroid hormones in plasma in the early post-traumatic phase with and without modification by nutritional therapy adapted to metabolism].

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Amino Acids↗

PubMed1981

[T3-hyperthyroidism under the aspects of secretion and peripheral production of thyroid hormones (author's transl)].

In contrast to T4/T3-hyperthyroidism, where T4, T3, and r-T3 serum concentrations (SC) are elevated, in T3-hyperthyroidism the T3-SC alone is increased, whereas T4-SC is normal and r-T3 may be decreased. Endogenous labelling of T4 with 131I is increased in T3-hyperthyroidism similarly as in T4/T3-hyperthyroidism, clearly reflecting an increased thyroidal formation of T4 in T3-hyperthyroidism. The contradiction of a normal SC to T4 in the presence of enhanced thyroidal formation of T4 may be explained by increased peripheral T4-deiodination. Since in T3-hyperthyroidism T3-SC are elevated whereas r-T3-SC are decreased, there is good evidence for a shift in T4 conversion.

Humans↗

PubMed1981

[Determination of endogenous labelling of thyroid hormones during a radioiodide test in euthyroid goiter patients and hyperthyroid patients (author's transl)].

The administration of a diagnostic dose of radioiodide, as in the radioiodide uptake test, results in the formation and secretion of radioactive thyroid hormones (endogenous labelling). In this report a method is described by which thyroid hormones are chromatographically isolated from serum, with the simultaneous assessment of the incorporated radioactivity over a period of time. A low-level counter was used to measure the small amounts of activity present. By this method the hormone phases during a radioiodide uptake test may be better evaluated. The present results show a good diagnostic discrimination between euthyroidism and borderline or definite hyperthyroidism (by a factor of 10 and 40, respectively). The influence of factors such as a small intrathyroidal iodide pool need, or course, to be considered. Hence, by taking into account such parameters as the intrathyroidal iodide pool, the hormone clearance etc, a technique for the measurement of thyroid hormone secretion can be developed.

Goiter↗