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Biomedical subjects

F Kokot

Publications and source records attributed to F Kokot.

At least 343 records · Page 19Linked to original sources
PubMed1985

Influence of phosphate restriction, keto-acids and vitamin D on the progression of chronic renal failure.

Progression of renal failure was investigated in a prospective follow-up study of 60 patients with mild and 100 patients with advanced renal failure. Phosphate restriction in mild and protein restriction in advanced renal failure can delay the progression rate of patients with chronic renal insufficiency. Simultaneous administration of Vitamin D does not effect the progression. Administration of keto-acids to the low protein diet has a strong delaying effect on the progression rate.

Dietary Proteins↗
PubMed1985

[Vitamin A status of patients with chronic renal failure in relation to renal osteodystrophy].

In patients with chronic renal insufficiency and dialysis patients as well as in normal persons determinations of vitamin A in the serum and in the bone were performed and related to the parameters of the bone metabolism and to the histomorphometric investigation of the bone. The vitamin A serum levels were significantly increased in the two groups of patients, however, did not show any differences between the patients with an osteoidosis or the combination of osteoidosis and fibroosteoclasia. There were no correlations to calcium, phosphorus, PTH and to the alkaline phosphatase as well as to the individual histomorphometric data. The vitamin A content of the bone was low and did not show any differences to the normal persons. On the other hand, there were significant relations between the parathormone and the parameters of the regeneration and the absorption of the bones. An additional influence of vitamin A on the bone disturbance, eventually by the activation of the osteoclasts cannot be excluded.

Adult↗
PubMed1985

[Sleep disorders].

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Diagnosis, Differential↗
PubMed1984

[Is there a relation between the renin-angiotensin-aldosterone system and vasopressin secretion in essential hypertension?].

103 patients with mild or moderately severe essential hypertension and 35 healthy normotensive subjects were examined. In all patients examined plasma osmolality, plasma renin activity and plasma level of vasopressin and aldosterone were estimated twice: first after administration of a diet with a sodium chloride content of 100 to 120 mmol/a day and 8 hours recumbency and a second time after 3 days of dietary sodium chloride restriction (20 mmol/a day) and 3-4 hours upright position. In hypertensives independent of the behaviour of the plasma renin activity similar values of the plasma osmolality, the plasma level of vasopressin and the aldosterone level could be established as in healthy persons. In contrast to normals in hypertensive subjects no significant correlation between plasma osmolality or plasma renin activity and plasma level of vasopressin and aldosterone was stated. In spite of normal levels of vasopressin and aldosterone a significant correlation between the plasma level of vasopressin and aldosterone and the systolic blood pressure was found in hypertensive patients. From the results obtained in this study follows that in hypertensive patients the plasma osmolality is only of secondary importance for the secretion of vasopressin and aldosterone and for the plasma renin activity. The importance of plasma vasopressin and aldosterone in the pathogenesis of hypertension seems to be probable but not yet unanimously proved.

Adult↗
PubMed1984

[Effects of L-arginine on glucagon and insulin secretion in patients with acute kidney failure].

In 20 patients with acute renal failure and 11 normal persons the behaviour of the glucagon and insulin secretion was examined after administration of L-arginine. Under standard conditions the glucagon level was significantly higher in the acute renal insufficiency than in the normals. Increased glucagon levels could be stated in the anuric/oliguric as well as in the polyuric phase. After administration of L-arginine in the acute renal failure a significantly higher increase of the glucagon level, but a significantly lower increase of the insulin concentration could be observed than in healthy persons. On account of these findings apart from the endocrinological changes stated also other factors seem to be involved in the pathogenesis of the carbohydrate intolerance in acute renal insufficiency.

Acute Kidney Injury↗
PubMed1984

[Is there a relation between parathormone and prolactin secretion in patients with acute and chronic kidney failure?].

In 14 healthy persons, 31 patients with acute and 13 with chronic renal failure the influence of alpha-bromocriptine on the PTH and prolactin level in the blood serum was investigated. In all subjects examined alpha-bromocriptine caused a decrease of the prolactin level. In acute and chronic renal failure simultaneously a decrease, on the other hand in healthy persons an increase of the PTH-concentration was observed. In all groups examined no correlation between the PTH and the prolactin level could be stated. In the light of the results obtained in this study the existence of a direct PTH-depending prolactin secretion seems to be questionable.

Acute Kidney Injury↗