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F Khadzhipetkov

Publications and source records attributed to F Khadzhipetkov.

4 recordsLinked to original sources
PubMed2004

[Micrometastases in patients with colorectal cancer: markers for metastatic potential or proofs for residual disease].

It is know that bone marrow micrometastases are an indicator of poor prognosis in patients with epithelial tumors. At the same time little is known if they reflect minimal residual disease or cells distribution and marked metastatic potential. We aimed to perform a clinical study, which though with little gathered clinical material has a direction--investigation of bone marrow in patients with colorectal cancer by the time of surgery, carefully rendering an account of staging and performing curative resection. In intraoperatively done bone marrow biopsy with following investigation for cytoceratin 19 positive cells we found ol presence of metastatic cells in some the studied patients. Finding micrometastases in patients with colorectal cancer is a marker for more agressive course of the disease and for the need to change some of recent methods of treatment.

Biomarkers, Tumor↗
PubMed1996

[Intraoperative abdominal echography].

Experience with and the impressions of adopting intraoperative abdominal echography in eighteen patients, aged 26 to 73 years, 9 men and 9 women, are shared. The distribution of patients by pattern of diseases is as follows: colorectal carcinoma--4 cases, liver echinococcus--one, gastric carcinoma--one, hepatocellular carcinoma--one, cholangitis acuta purulenta-one, echinococcus of lung and liver--one, calculous cholecystitis with choledocholithiasis--five, and carcinoma of ductus choledochus--one. Fifty intraoperative abdominal echographies and one intrathoracic supradiaphragmatic echography of the liver are performed. Intraoperative abdominal echography of tumors involving organs of the digestive tract contributes to specify the staging of the neoplastic process. In liver echinococcus it determines precisely the number of cysts and diagnoses impalpable cystic formations, while in choledocholithiasis it documents the presence of calculi in the biliary tracts and eventual dilatation of intrahepatic ones. In five patients intraoperative abdominal echographic is done in conjunction with intraoperative fiber choledochoscopy.

Abdomen↗
PubMed1994

[Peritonitis of large-bowel origin--complicated colorectal carcinoma].

A total of 803 patients presenting colorectal carcinoma are operated on over a 14-year period (1979 through 1992). In 272 cases (33.8 per cent) the disease runs a complicated clinical course. Perforative peritonitis is recorded in 29 cases-10.6 per cent of the total number of patients with complicated course, and 3.6 per cent of the total number subjected to operation. Ileus peritonitis free of perforation is discovered in twenty-seven cases-9.5 per cent of 272, and 3.23 per cent of the total number-803. The microbiological study of abdominal cavity exudate from the patients with ileus peritonitis points to predomination of anaerobic micro-organisms, having an essential practical bearing on performing adequate perioperative and postoperative antibiotic treatment, and peritoneal cavity lavage during the operation. Radical two-staged operations with removal of the perforated neoplastic process in the first stage and preternatural anus formation are the method of choice. Palliative operations leaving the perforated carcinoma within the abdominal cavity account for 100 per cent lethality. A radical one-staged operation is indicated only in the event of localized peritonitis, young patients, preserved good general condition, usually following right hemicolectomy.

Adenocarcinoma↗