At the occasion of the discovery of an amoebiasis focus in a psychiatric hospital (36,2 % of the patients were Entamoeba histolytica carriers), the authors insist on the importance of systematical and continued coprological controls. They observe that the two means of fight used together, the environment and the mass treatment, have strongly limited the propagation of parasitosis. By this way they note efficiency of the association of the medicinal polyvalent and contact amoebicides.

Amebiasis↗

PubMedDate not supplied

Thromboxane B2 blood levels and incipient system clotting in heparin free hemodialysis.

Clotting of the extracorporal system is the main complication of heparin free hemodialysis performed in patients with an increased risk of bleeding. The authors compared thromboxane B2, platelet factor 4, beta-thromboglobulin, and thromboelastography in systemic blood as markers of thrombogenicity during hemodialysis in eight patients with an increased risk of bleeding. Measurements were performed during hemodialysis with and without heparin. Thromboxane B2 levels in centrifuged blood were evaluated by an 125I assay system using a special extraction with mini-columns and magnetic separation (normal 32-64 pg/ml). At the onset of hemodialysis, thromboxane B2 concentrations in the inflow arterial blood line were lower than normal (30 +/- 23 pg/ml). Thromboxane B2 increased (97 +/- 105 versus 40 +/- 26 pg/ml) and was significantly higher during heparin free hemodialysis than during hemodialysis with heparin (p = 0.01, Wilcoxon matched pairs signed rank test). The highest values were observed in 5 cases with signs of clotting (152 +/- 122 pg/ml). Among the investigated parameters, thromboxane B2 proved to be the most significant serum parameter correlated with platelet activation and the consequently increased risk of incipient clotting during heparin free hemodialysis.

Aged↗

PubMedDate not supplied

[Concepts of cellular and molecular biology used in virology].

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Animals↗

PubMedDate not supplied

[Age dependence of collagen structures of the human heart].

Polarization-microscopical measurements combined with silver-staining methods and morphometrical estimations (countings) were used to study the collagen fiber structures of the fibrosa of human atrioventricular valves as well as of the chordae tendineae of the right and left heart with regard to age and sex differences. Measurements and countings were performed on histological sections of the tricuspid valve, bicuspid valve and the chordae tendineae from a total of 87 subjects of both sexes, who were divided into three age groups (1st and 2nd, 3rd to 5th and > 6th decade) with six to seven persons in each group. Differences were found between the right and left atrioventricular valve and analogously between the chordae tendineae of the right and left heart in middle-aged persons with regard to the frequency-distribution H(Q) of the quotients of path differences and the proportion of silver stained collagen fibers as compared to unstained. These differences can be interpreted as an expression of different functional load (low-pressure vs. high-pressure system). Under higher pressure, the proportion of unsilvered fibers with a higher mean value of quotient (mainly assigned to type I collagen) at the expense of the silvered fibers (classified as type III collagen) becomes greater. With advancing age the total amount of collagenous fibers and the proportion of unsilvered fibers increases. Simultaneously, the mean values of the quotients (especially Q (unsilvered)) increase slightly. The study revealed sex differences for the tricuspid valve and the chordae tendineae of the right heart (low-pressure system) only.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗