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Biomedical subjects

F Kaindl

Publications and source records attributed to F Kaindl.

At least 55 records · Page 3Linked to original sources
PubMed1981

[Computer-assisted long-term ECG analysis in patients with artificial trial pacemaker (AAI) (author's transl)].

Control of AAI-function is limited. To investigate the efficacy of AAI-stimulation, a computer-assisted analysis system for long-term ECG records was developed using "Multipass-Scanning I". 12 patients (5 females, 7 males, 33--78 years old with AAI) underwent Holter-monitoring for 24 hours continuously. THe ECGs of 5 among the collective with heart rate programmable AAI were recorded three times each with different AAI stimulation rates (50--80 b.p.m.). The number of AAI-induced heart beats in relation to the total number of QRS-complexes (AAI-QRS%) was 43 +/- 37% mean. AAI-QRS% during day showed a significantly lower distribution (35 +/- 38%, p less than 0.01) than during night (58 +/- 40%, p less than 0.001). Using an AAI-stimulation frequency of 50 b.p.m., only 9% of the heart beats were AAI-induced during day. Whereas AAI-QRS% increased to 72% during night in patients with AAI-stimulation frequency of 70 b.p.m. The interval between the PM-spike (S) and the following answer of the heart, i.e. SR-interval, demonstrated also a circadian behaviour: SR max occurred between 10 p.m. and 2 a.m. It was significantly prolonged to the SR min. (9--31%, m 20%, p less than 0.0001), which occurred between 9 a.m. and 4 p.m. So the presented computer-assisted long-term ECG analysis system for AAI-pacemakers is able to evaluate the efficacy of AAI with regard to different AAI-stimulation rates. The quantity of AAI-induced heart beats is dependent on patient's heart rate, its circadian behaviour and the stimulation rate of the AAI. The SR-interval also demonstrated a significantly circadian pattern, which can be related to the vagus-influenced PQ- and also AH-interval.

Adult↗
PubMed1980

Primary pulmonary hypertension: follow-up of patients with and without anorectic drug intake.

Long-term follow-up of 75 patients with pulmonary hypertension developing their symptoms prior to 1970 was performed. Anorectic drug intake, survival, repeated haemodynamic measurements and past and present symptoms were evaluated. The higher incidence of pulmonary hypertension at that time was strongly related to anorectic drug intake. No difference in the long-term survival was found in patients with and without anorectic drug intake. None of the patients showed normalization of the pulmonary pressure and the changes were unpredictable from the values found at the initial measurements. Long-term survival is possible even in patients with very high pulmonary arterial pressure. Improvement of the haemodynamic indicators was more frequent in patients with anorectic drug intake. In approximately 30% of the patients with anorectic drug intake a decrease in symptoms was observed while in none of the other patients was such a decrease found. It therefore seems that at least some of the patients with pulmonary hypertension and a history of anorectic drug intake adapt themselves better than those without anorectic drug intake.

Adult↗
PubMed1980

[Abnormal pulmonary function in patients with acute uncomplicated myocardial infarction (author's transl)].

Pulmonary function has been evaluated in patients with acute uncomplicated myocardial infarction. Vital capacity,, flow-volume curves, oscillatory resistance and arterial oxygen tension have been measured within 24 hours of onset of symptoms and were repeated on day 4, 7 and 13 after infarction. In a mean interval of 6 months another measurement was done. Vital capacity was significantly reduced on the 4th day, arterial oxygen tension was also lowest on day 4, but no significant changes were seen. The expiratory flow data revealed a significant increase in the maximal expiratory flow as well as of maximal expiratory flow at 50% of the vital capacity in the second week after infarction. Oscillatory resistance was significantly increased on the first day and could be significantly reduced by inhalation of an anticholinergic broncholytic agent. These changes suggest that pulmonary function is reduced in patients with acute myocardial infarction, probably due to increase in pulmonary water and the maximal changes are present in the first week. The significant reduction of the oscillatory resistance from the first to the fourth day without significant changes of other parameters suggest an additional mechanism, which might be mediated by the vagal nerve.

Adult↗
PubMed1979

[Myocardial revascularization in threatening extension of myocardial infarction (author's transl)].

Myocardial revascularization was performed in 13 patients between two and 14 days following initial infarction because of impending re-infarction. The diagnosis of impending re-infarction was made on the basis of the following criteria: myocardial infarction; repeated stenocardia despite medical treatment; renewed ST-T changes in the ECG. The intra-aortic balloon pump was installed in 7 patients for haemodynamic reasons (shock, massively raised pressure in the pulmonary artery). 12 patients survived the surgical intervention and were eventually discharged free of stenocardia. The presented findings suggest that surgical intervention in impending re-infarction appears of value in those cases which have not been satisfactorily controlled by conventional medical treatment.

Adult↗
PubMed1979

[A study of a swimming training programme in the rehabilitation of patients following myocardial infarction (author's transl)].

A special swimming programme was initiated during the course of rehabilitation of patients after myocardial infarction with additional disturbances of the musculoskeletal system. Allowance was made for aspects of individual training requirements. Patients were divided in two groups according initial values of physical working capacity: One group contained patients with less than 80% of the normal work capacity, the other those with borderline normal values. The first group showed an average increase of 35% in the initial values during a one-year period of swimming training once a week. The other group with practically normal initial values showed only a slight or negligible increase. Serum lipid levels were unchanged in both groups. No serious side effects were encountered in more than 3000 patients hours. However, no prediction of the risks of this type of training as compared to other forms of physical exercise in patients recovering from myocardial infarction can be made from this study.

Adult↗
PubMed1979

Radionuclide assessment of cardiac performance and myocardial perfusion in congestive cardiomyopathies.

To determine the reliability of radionuclide techniques in the diagnosis of congestive cardiomyopathy (COCM), the function of the right ventricle (RV) and left ventricle (LV) was evaluated in 32 patients with COCM and 21 normal subjects using radionuclide angiography (first pass and gated blood pool scan) combined with quantitative 201 thallium (Tl) myocardial perfusion imaging. In COCM parameters of RV and LV performance were significantly reduced (p less than 0.01); regional wall motion analysis revealed a reduced radial shortening ability (p less than 0.05). 201 Tl distribution within the myocardium was not different between COCM and N; however, segmental 201Tl-uptake was significantly reduced (p less than 0.01). RV free wall was visualized on 201Tl scan in 80% of patients with COCM. There was no correlation between RV free wall visualization and RV hemodynamics. Thus these scintigraphic aspects provide an atraumatic and sensitive technique for the evaluation of patients with COCM.

Adult↗
PubMed1979

Assessment of left ventricular performance and myocardial viability using quantitative radioisotope techniques.

The diagnostic value of a combined radionuclide technique was compared with conventional angiocardiographic techniques in 60 patients with coronary artery disease. Quantitative 201Tl myocardial imaging combined with radionuclide angiocardiography using 99mTc-HSA provided a safe and accurate method for the assessment of left ventricular performance. The defects on the 201Tl images correlated with the severity of asynergy seen on the contrast ventriculogram. Static imaging alone distinguished hypokinetic from akinetic or dyskinetic areas. However, using both tracer techniques, akinesis could bedistinguished from dyskinesis. In patients with disturbed left ventricular function, cardiac transit times correlated with haemodynamic changes, and left ventricular ejection fraction was the most sensitive index. Thus, this combined radionuclide approach provides data for the evaluation of overall and regional wall function. A major advantage of this non-invasive auantitative technique is its applicability to the critically ill patient at the bedside.

Adult↗
PubMed1978

Assessment of regional wall motion in coronary artery disease using radionuclide methods.

72 patients with CAD, 10 patients with congestive cardiomyopathies and 10 normal subjects were evaluated by radionuclide angiography. Comparison with contrast angiography showed good results for LVEF (r = 0.83). Regional asynergies observed in the radionuclide angiography correlated well with defects in thallium scintigrams. Extent of abnormal wall motion was measured and compared with normals, appreciating the deviation from the normal mean radial shortening. Good correlation could be demonstrated with radionuclide ventriculography. In 80% of congestive cardiomyopathies the right ventricle wall became visible in the thallium scintigram.

Cardiomyopathies↗
PubMed1977

Pre-excitation of the ventricle associated with total intra His bundle block.

A case with total intra-His bundle block and intermittent pre-excitation syndrome is presented. During A-V conduction there was a P-delta interval of 130 msec. with a P-A interval of 20 msec., an A-H interval of 60 msec. and an H-V interval of 50 msec. During rapid atrial pacing the P-delta interval increased primarily due to an A-H1 prolongation and a Mobitz type 2 block and total A-V block occured at increasing rates showing H1 following every A spike. The escape beats showed a normal width of the QRS complexes with preceding H2 spikes. After administration of Ajmaline the bypass tract was blocked and constant total A-V block occurred. It was concluded that there was a constant total intra-His bundle block and a nodoventricular or fasciculoventricular bypass tract with prolonged conduction to the ventricle. This bypass tract blocked sometimes spontaneously and could also be blocked by rapid atrial pacing and administration of drugs. The close anatomic proximity of the His bundle and Mahaim fibers is responsible for the simultaneous block resulting in total atrioventricular block.

Aged↗