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Biomedical subjects

F Joffre

Publications and source records attributed to F Joffre.

At least 145 records · Page 8Linked to original sources

[The place of intraluminal angioplasty in a vascular surgery department].

The advent and rapid strides made in the use of percutaneous intraluminal angioplasty (P.I.A.) in the treatment of chronic obliterating arteriopathies of the lower limbs have provoked a great deal of discussion. The exact place of this technique among the various therapies available is assessed in a different manner by radiologists, angiologists, and vascular surgeons. This report attempts to supply answers to two questions posed by certain authors in a more or less implicit manner: what is the importance of P.I.A. in relation to other therapeutic methods, and does P.I.A. have a marked diminishing effect on the need for surgery?

Angioplasty, Balloon↗

[Multilocular cyst of the kidney (author's transl)].

The authors report the 67th published case of multilocular renal cyst, noting that half of the published cases concerned children. Left lumbar pain led to the discovery of a palpable mass of the lower pole of the left kidney visible at urography. At echotomography, alternation between dense and fluid areas made it possible to eliminate a solitary cyst. Renal arteriography was disturbing by virtue of the persistent slight peripheral hypervascularisation after the injection of angiotensin. Diagnostic doubt and the absence of any clearly defined limit between healthy kidney and pathological kidney led to nephrectomy. Histopathology : a thick capsule separated from the healthy kidney a series of cystic structures with no intercommunication between them, nor with the excretory system. Each cyst was lined with an endotheliform single layer epithelium with no renal tissue in the intercystic fibrous separations. The authors emphasise the difficulty of offering an opinion as to the aetiopathogenesis of this lesion which certain feel to be a dysplasia and others as a transitional form with nephroblastoma.

Angiography↗

[Ultrasonography in the diagnosis of adrenal tumors (author's transl)].

A prospective study was conducted to assess the value of ultrasonography in the diagnosis of adrenal tumors. A limited number of cases (29 patients) was studied, to reduce the possible effects of human and technological progress. Ultrasonography can detect most adrenal tumors larger than 25 mm in diameter, more easily on the right than on the left. The solid or fluid nature of the tumor can be distinguished, but the benign or malignant etiology of the mass can only be determined when there is local and regional spread. Ultrasonography is particularly useful when a suspicious adrenal mass is seen on nephro-urotomography. The indications for ultrasonography have to be reconsidered, however, as a function of the results obtained with computed tomography.

Adenoma↗

[Treatment of renal artery stenosis by percutaneous transluminal angioplasty (PTA) (author's transl)].

The preliminary results of treatment of the stenosis of renal artery by the transluminal percutaneous angioplasty (PTA) were presented. 6 patients were treated by the Gruntzig technique, 4 of the 5 patients probably having renovascular hypertension were returned to normal tension 2 to 5 months after treatment. The 6th patient had hypertension with severe renal insufficiency. The PTA was performed for the purpose of the inhibition of progressing renal insufficiency. This patient was stabilized. This preliminary experience show great interest of this technique.

Adult↗

[The contribution of gallbladders' infusion tomography in the diagnosis of acute cholecystitis (author's transl)].

The detection of opacification of the wall of the gallbladder after the intravenous injection of hydrosoluble iodinated contrast medium (gallbladder parietography) was sought in 82 patients suspected of suffering from acute cholecystitis. In 35 cases, the examination was negative and operation or the clinical course made it possible to eliminate the diagnosis of acute cholecystitis. In 47 cases, it was positive. The diagnosis was confirmed in 39 cases out of 40 patients undergoing surgery. The appearance of the opacification makes it possible to distinguish two types of positive gallbladder parietography: -- with a thin wall and gallbladder of normal size, corresponding to moderate inflammatory lesions; -- with a thickened wall associated with a large gallbladder corresponding to major inflammatory lesions. The examination is simple, reliable, may be carried out as an emergency and combined with intravenous urography. The diagnosis of acute cholecystitis may be made in difficult causes, and appropriate therapeutic steps taken.

Acute Disease↗

[Radiologic exploration of pheochromocytoma].

The authors present their experience of radiological investigation of pheochromocytoma based on a series of 80 patients. The aim of radiological investigation are defined and primarily involve a topographical diagnosis and a preoperative assessment of the tumour. Each technique is discussed critically and their indications defined. At present, nephrourotomography by rapid injection is the technique of choice for the diagnosis of an adrenal lesion. Echotomography and scanning do not give as much precision. The assessment of the tumour requires above all arteriography, but staggered measurements from the vena cava is a promising new technique.

Adolescent↗

[Value of vascular tests in the diagnosis and therapeutical indications of pulmonary embolism on a pneumological background (author's transl)].

The diagnosis of mislaying forms of pulmonary embolism, where even angiography was not pathognomonic, induced the use of a phlebography on lower limbs in patients where this diagnosis was suspected. The revelation of a distal thrombo-phlebitis and even more so an iliocaval one, becomes a major value when the clinical and paraclinical data remained arguable. The comparative study of diagnostic usual clinical and paraclinical elements (radiographies, E.C.G., gasometries and scintigraphies) confirmed, in 22 patients, the value of phlebography. On a pneumological background, it is useful to perform this examination, most of the time : a) on patients over 55, when a cardiorespiratory decompensation remained unexplained in a patient with chronic respiratory insufficiency, or even an unproved hemoptysis; b) but mostly before 55, in case of painful pneumopathy above all if it is bilateral and recurring, or in case of paroxysmal bronchospasm without atopic ground, when a belated asthma could be thought of. Finally vascular tests induced the fitting in situ of a clamp or "umbrella" in the vena cava in 7 patients out of 22.

Adult↗

[Problem posed by the prevention and detection of colorectal cancers].

The incidence of colonic and rectal carcinoma is in constant progression. The detection and destruction of polyps is the only effective means of reducing the number of adenocarcinomas. The technical means of detection are well known and fully proved: rectosigmoidoscopy, thin layer double contrast enema, colonoscopy. The true problem is that of the cost of this prevention. It is important to define high risk groups in which these tests should be carried out as a routine. Furthermore it is necessary to know whether blood tests or examination of the stools may be considered as a means of detection of polyp or at least certain types of potentially malignant polyp. without suggesting a considerable increase in the number of medical investigations, one may hope for better use of sigmoidoscopy and double contrast barium enema. These two examinations represent undoubtedly the essential factor in the diagnosis of colonic and rectal tumours.

Adenocarcinoma↗

[The contribution of nephro-urotomography in the diagnosis of unilateral non-functioning kidney in the adult (author's transl)].

The aetiological diagnosis of a unilateral nonfunctioning kidney is achieved by angiographic or retrograde techniques. Pyelography indicates only that organ is non-functioning. 71 patients were explored by nephro-urotomography carried out using high doses of contrast medium (2 cm3/kg) with rapid injection (10cm3/sec.) and repeated tomographic sections taken during the first minute after injection. These tomographic sections, three in number, made it possible to study the three phases of the nephrogram: cortical nephrography, cortico-medullary nephrography and tubular nephrography. The aim of this study was to assess the contribution of this technique in the aetiological diagnosis of a unilateral non-functioning kidney. In the majority of cases it is possible to suspect the vascular or neoplasic origin of the non-functioning kidney. Obstructive non-functioning kidneys have two distinct nephrographic appearances. Pelvic and retroperitoneal obstructions are visualised chiefly during the phase of cortical nephrography, which shows marked parenchymatous atrophy with the presence of rounded intrarenal lacunae. By contrast, obstruction secondary to pyelo-ureteral junction syndrome results in total destruction of the parenchyma. The phenomenon of total corporeal opacification plays a major role in the visualisation of the fibrous speta which form the limits of the pseudocystic pockets. In these patients, the contribution of study of early nephrograms is less evident. Bacillary non-functioning kidneys have an analogous appearance characterised by the particular frequency of abnormal opacities, calcified ormastic. Thus the aetiological diagnosis of a unilateral nonfunctioning kidney may be obtained in the majority of cases. This permits more judicious selection of those cases requiring angiography or retrograde exploration necessary to pre-operative assessment.

Humans↗