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Biomedical subjects

F J Schulte

Publications and source records attributed to F J Schulte.

16 recordsLinked to original sources
PubMed1978

The etiology of neurosensory hearing defects in preterm infants.

We retrospectively investigated the influence of gestational age, perinatal risk, and the duration of incubator care periods in 193 surviving preterm infants with a gestational age between 28 and 36 weeks raised in our intensive care nursery incubators from 1965--1967. 24 (12.4%) of the children showed definite neurosensory hearing defects, which were particularly encountered in the high frequencies. No correlation could be substantiated between hearing difficulties and hyperbilirubinemia, streptomycin application and gestational age. This study does not support the assumption that the duration of noise exposure in currently used incubators is a major determinant for the development of deafness in otherwise healthy preterm infants. Our study did show, however, a strong correlation between the sum of all perinatal risk factors and neurosensory hearing loss.

Audiometry↗
PubMed1977

The ontogeny of sensory perception in preterm infants.

The extra- vs intrauterine development of both visual and auditory cortical evoked response patterns was compared at 33, 37 and 40 weeks conceptional age. The maturation of visual cortical evoked responses is retarded in infants at 37 and 40 weeks conceptional age when born with a gestational age of less than 32 weeks, which thus implies a long extrauterine life span. The maturation of the auditory cortical evoked responses is not influenced by premature exposure to the extrauterine environment. The results are explained on the basis of the particular central nervous system growth spurt periods and a thus defined vulnerable period of different brain structures.

Auditory Cortex↗
PubMed1977

Rapid eye movement sleep, motoneurone inhibition, and apneic spells in preterm infants.

Not principally different from the results obtained in more mature subjects, monosynaptic reflex excitability of spinal motoneurones in preterm infants decreases during active sleep. However, in preterm infants the electric reflex response is not abolished, and is not even continuously depressed during the entire active sleep period. Spinal motoneurone inhibition is demonstrable only during certain periods of active sleep, and it is during this state of decreased spinal motoneurone excitability when apneic spells predominantly occur.

Apnea↗
PubMed1977

Apnea.

Explore the source record for details and available documents.

Apnea↗
PubMed1976

Apneic spells and sleep states in preterm infants.

The incidence of apneic spells during different sleep states active sleep, quiet sleep, and undifferentiated sleep was determined in eight preterm infants of 30 to 35 weeks' conceptional age, by means of a polygraphic recording technique. They were free of perinatal and postnatal complications other than apnea. During their active or rapid eye movement (REM) sleep they showed significantly more apneic episodes which were also longer lasting and they were accompanied by bradycardia of a greater severity. The organization of the immature nervous system with a preponderance of inhibitory synaptic connections and the additional inhibition of spinal motoneurons during REM sleep are likely to be the cause of apneic spells in otherwise "normal" preterm infants.

Apnea↗
PubMed1976

Transcutaneous PO2 monitoring in routine management of infants and children with cardiorespiratory problems.

Results are reported concerning the clinical application of the transcutaneous PO2 method (tc PO2 method) according to Huch et al. for monitoring arterial PO2. Thirty long-term continuous tc PO2 recordings were made in 22 ventilated children and infants with cardiorespiratory problems in four different pediatric intensive care units (Zürich, Göttingen, Kassel, and Mainz). These recordings were compared with 132 arterial PO2 determinations made during the same period of time. There was a linear relationship and a close correspondence between arterial PO2 and tc PO2 (r = .94). The continuous recordings have shown that the variability of PO2 is much greater than assumed so far by single blood gas analysis. This fact restricts greatly the value of single samples. Continuous tc PO2 monitoring has proved to be a great help in optimal respirator setting.

Child↗
PubMed1976

[Prematurity, incubator noise and hearing disturbances (author's transl)].

1. An audiologic follow-up study was done on 62 children, ages 10-11 years. All children had been pre-term infants, with a gestational age between 29 and 35 weeks. They had been maintained in an incubator for a period of 21-61 days. The children had frequently received ototoxic antibiotics in the newborn period, and had been subject to many perinatal risk factors with a high "non-optimal score." 2. 44 children (71%) were found to be audiologically normal, whereas 8 (13%) had minor auditory defects and 10 (16%) had major hearing defects. 3. There was a significant correlation between hearing defects and the "non-optimal score": children with the most difficult perinatal course were more likely to develop hearing difficulties. 4. This study was unable to support the assumption that the hearing loss found was due to high incubator noise levels: (a) The incubator noise level was slightly below the probably dangerous limit for noise exposure. (b) There was no correlation between the hearing impairment and the length of incubator stay. (c) The type of hearing defect was not generally consistent with that associated with noise pollution.

Adult↗