Search PubMed⌕ Search

Biomedical subjects

F J Roumen

Publications and source records attributed to F J Roumen.

23 records · Page 2Linked to original sources

Ovulation prediction by monitoring salivary electrical resistance with the Cue Fertility Monitor.

The purpose of this study was to investigate the potential relationship between the salivary electrical resistance, as measured by the Cue Fertility Monitor, and the time of ovulation. Twenty-seven cycles in 18 volunteers were analyzed. A slight correlation could be demonstrated between the day of salivary electrical resistance peak and the day of luteinizing hormone (LH) peak. However, the changes in salivary electrical resistance values, arranged to the day of LH peak, were not statistically significant. The days of salivary electrical resistance peak in relation to the day of LH peak were not reproducible in individual women. The apparent relationship between the day of salivary electrical resistance peak and the day LH peak might be explained by the methodology used. It is concluded that measuring the salivary electrical resistance is of no use in predicting the day of ovulation.

Adult↗

[Fetal anemia].

Explore the source record for details and available documents.

Adult↗

Treatment of infertile women with a deficient postcoital test with two antiestrogens: clomiphene and tamoxifen.

Twenty-two infertile women with repeated deficient results in the postcoital test received clomiphene citrate or tamoxifen. The patterns of luteinizing hormone, follicle-stimulating hormone, prolactin, 17 beta-estradiol (E2), and progesterone were examined during the follicular and periovulatory phases of the menstrual cycle, as were the cervical mucus characteristics. Under clomiphene treatment, an overproduction of E2 was observed (P less than 0.01), which did not result in an improvement of the cervical mucus characteristics. The pH of the endocervical mucus was lower (P less than 0.01). Under tamoxifen treatment, the serum E2 levels were higher (P less than 0.05) and normalized. Higher spermatozoa penetration meter scores were observed during the preovulatory and periovulatory periods, whereas the pH of the endocervical mucus was not lowered. These data support that tamoxifen may be preferential to clomiphene in treating this kind of infertile woman.

Adult↗

Hormonal patterns in infertile women with a deficient postcoital test.

Twenty-two women in whom a routine infertility workup had shown no abnormality except for repeated deficient results in the postcoital test (PCT), the patterns of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), 17 beta-estradiol (E2), and progesterone (P) were examined during the follicular and periovulatory phases of the menstrual cycle. Cervical mucus (CM) characteristics were also investigated during the pre- and periovulatory phases and scored using a CM score and a sperm penetration meter (SPM) score. The results were compared with those of a control group of seven women with proven fertility. No differences were found between the CM scores of both groups, whereas the SPM score was lower (P less than 0.1) in the infertile group. The preovulatory serum levels of E2 were lower (P less than 0.1) in the infertile group, while the serum levels of PRL (P less than 0.1) and FSH (P less than 0.1) were constantly higher in this group. The mean serum levels of LH and P were almost equal in the two groups. It is concluded that a deficient result in the PCT can be indicative of deviated hormonal patterns in an infertile woman even when the routine fertility investigation is suggestive of a normal ovulatory cycle.

Adult↗

The course of delivery after previous cesarean section.

Of 249 women whose last pregnancy was terminated by a cesarean section, 57 (22.9%) were delivered again by a primary cesarean section. The other 192 (77.1%) were allowed to attempt vaginal birth. Of these, 151 (60.6%) were successful, and 41 (16.5%) underwent a secondary cesarean section. The percentage of successful vaginal births was correlated with the indication for the previous cesarean section. There was one case of incomplete uterine rupture. The maternal morbidity was lowest in the group who had a vaginal delivery. One child developed an Erb-Duchenne paralysis in addition to a shoulder dystocia. The condition of the vaginally delivered children was not different from the condition of the children born by a primary cesarean section. It is concluded that there are sufficient arguments for continuing the policy of 'once a cesarean section, trial of labor after selection'.

Cesarean Section↗