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Biomedical subjects

F J Bone

Publications and source records attributed to F J Bone.

10 recordsLinked to original sources
PubMed1990

Lyme disease.

Explore the source record for details and available documents.

Family Practice↗
PubMed1989

Staphylococcal food poisoning from sheep milk cheese.

Cheese made from sheep milk was implicated in food-poisoning incidents in December 1984 and January 1985. Bacteriological examination of batches of cheese failed to reveal a viable pathogen but enterotoxin A produced by Staphylococcus aureus was present. This was the first time that enterotoxin was detected in a food produced in the UK which was associated with poisoning and from which viable Staph. aureus could not be isolated. Subsequent detailed examination of milk, yoghurt and cheese from the same producer revealed that contamination with Staph. aureus was associated with post-infection carriage as well as clinical illness in ewes on the farm. Strains producing enterotoxon. A were still intermittently present in the bulk milk used for cheese production nearly 2 years afterwards, apparently in the absence of clinical illness in the sheep. The possible effects of heat treatment are discussed. Any changes in legislation should cover all non-human mammalian milk used for human consumption.

Animals↗
PubMed1987

A comparative study of cefotetan and metronidazole against metronidazole alone to prevent infection after appendectomy.

The role of metronidazole in reducing the incidence of infectious complications after appendectomy has been established, but the value of an additional antibiotic to act against aerobic pathogens remains controversial. Patients who received 2 grams of cefotetan intravenously at the time of appendectomy and those who did not were compared for the incidence of infection. All patients received 1 gram of metronidazole per rectum preoperatively and every 12 hours for five days postoperatively. Infection occurred in three patients who received cefotetan and 16 of those who did not (p less than 0.01). We conclude that a single dose of cefotetan, an antibiotic which is effective against aerobic and anaerobic organisms, produces a significant reduction in the incidence of infection when added to metronidazole in the management of patients after appendectomy.

Adolescent↗
PubMed1975

Meningitis due to an unusual type of Haemophilus influenzae.

An infant was admitted to hospital with suspected meningitis. Haemophilus influenzae type 'a' was isolated from cerebrospinal fluid (C.S.F.) and blood. Haemophilus meningitis due to types other than type 'b' is rare, and only a few due to type 'a' have so far been recorded. Investigations of the family are included together with a discussion of the implications for the diagnostic bacteriologist.

Antibodies, Bacterial↗
PubMed1972

Brain abscess due to Haemophilus aphrophilus: case report.

A temporal lobe abscess due to H. aphrophilus occurred in a child of 11 years, and was successfully treated by aspiration, chemotherapy, and excision of the abscess wall. The organism is an unusual cause of brain abscess and this is believed to be the first reported case in Britain.

Ampicillin↗