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Biomedical subjects

F I Jackson

Publications and source records attributed to F I Jackson.

61 records · Page 4Linked to original sources
PubMed1976

Scintigraphy of sacroiliac joints in acute anterior uveitis. A study of thirty patients.

HLA-B27 is a transplantation antigen found in a high proportion of patients with ankylosing spondylitis. Recently, an association has been shown to exist between HLA-B27 and acute uveitis, even in the absence of ankylosing spondylitis. We have examined the HLA antigen profile of 45 patients with acute nongranulomatous anterior uveitis and have confirmed this relation. In addition, using 90mtechnetium stannous pyrophosphate we have been able to demonstrate abnormal bone scan in 19 of 30 patients studied. Such abnormalities are limited to the sacroiliac joints but are otherwise the same as those seen in overt ankylosing spondylitis. Seven of the 19 patients did not have HLA-B27. These factors suggest that acute anterior uveitis may often represent a manifestation of a spondylitic diathesis even in the complete absence of any suggestive symptomatic or radiologic change and, in some cases, even though the antigenic marker HLA-B27 may be absent.

Adolescent↗
PubMed1976

Gallium-67 citrate scintiscanning in testicular neoplasia.

Gallium-67 citrate has been used to evaluate 19 patients with malignant tumors of the testes. Five patients with abnormal uptake of the radiotracer in the abdomen proved to have other evidence confirming metastatic spread to this site. Eight patients, with normal scan findings, surgery and lymphangiorgraphy, provided no conflicting evidence of disease although one of these patients has subsequently developed increased urinary gonadotrophin concentrations. Surgery caused an abnormal scan and such patients were excluded from the analysis pointing to the need for preoperative evaluation. The technique of 67-gallium scintigraphy appears of value in assessing the intra-abdominal spread of malignant tumors of the testes.

Adolescent↗
PubMed1976

Localization of gallium-67 citrate in salivary glands following radiation therapy.

Gallium-67 citrate was found to localize in the salivary glands of eight patients after therapeutic doses of radiation to a treatment field including the glands. In two patients, autopsy evidence to the effect that no primary disease was present to explain such uptake was obtained. In another two patients the abnormal uptake was not observed on follow-up. The recognition that radiation sialadenitis is a potential cause of false-positive gallium scintiscans is important in their interpretation.

Autopsy↗
PubMed1976

Localization of gallium-67 citrate in salivary glands following radiation therapy.

Gallium-67 citrate was found to localize in the salivary glands of eight patients after therapeutic doses of radiation to a treatment field including the glands. In two patients, autopsy evidence to the effect that no primary disease was present to explain such uptake was obtained. In another two patients the abnormal uptake was not observed on follow-up. The recognition that radiation sialadenitis is a potential cause of false-positive gallium scintiscans is important in their interpretation.

Autopsy↗
PubMed1975

Bone scintiscanning in the initial assessment of carcinoma of the breast.

Bone scans using 99mTc polyphosphate have been obtained in 174 patients with newly diagnosed carcinoma of the breast. This number represents 68 per cent of all patients registered with the disease in northern Alberta during the 12 months of the study. In nine patients, the roentgenograms were abnormal, but in 18, there was scintiscan evidence of metastatic disease involving bone, although one false-negative interpretation is included in this number. In another eight patients with normal or equivocal initial bone scintiscans, metastatic disease involving bone developed during a 12 months' period of observation.

Bone Neoplasms↗
PubMedDate not supplied

Ultrasound in the diagnosis of lymphoma: a review.

A retrospective review of the ultrasound examination of 138 patients suffering from lymphoma has been undertaken. The value of ultrasound in determining the extent of disease throughout the body has been demonstrated, as well as some of the uses of ultrasound in therapy. The limitations of ultrasound examinations are also described.

Digestive System Neoplasms↗