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Biomedical subjects

F I Jackson

Publications and source records attributed to F I Jackson.

At least 37 records · Page 2Linked to original sources

Multimodality detection of metastatic melanoma.

A retrospective evaluation of radionuclide liver and spleen scintigraphy (LS), ultrasonography (US), and computed tomography (CT) was performed in 88 patients who had pathologically proven cutaneous melanoma. In patients who had all three examinations (n = 24), the matrix analysis showed that CT was significantly more sensitive (0.94) in detecting intra-abdominal metastasis when compared to US (0.62, P less than 0.05) and LS (0.38, P less than 0.01). Sixty-four patients had only US and LS studies. In this group of patients US was found to be more sensitive than LS, 0.88 and 0.54 respectively (P less than 0.01). Furthermore, when CT was compared with US, CT was shown to detect metastases significantly earlier than US (P = 0.03). Overall, CT provided the most accurate means for detecting the intra-abdominal metastases of cutaneous melanoma.

Abdominal Neoplasms↗

Adenolipoma of the breast.

We here report a patient with an adenolipoma of the breast. The radiological features appeared to be characteristic. On mammography the mass was surrounded by a radiolucent ring and on ultrasonography the lesion was revealed as a well-defined, hypoechoic, lobulated and solid mass.

Adenoma↗

The cooling effect of tubular liquid flow during radiofrequency heating: the "rind" survival hypothesis.

The influence of flowing blood on temperatures reached in nearby tumor cells during localized radiofrequency (RF) hyperthermia may be critical for tumor cell survival. We have investigated the effect on the temperatures nearby of blood flowing in a vessel. Using 13.56 MHz capacitive RF, we heated gel phantoms containing a tube through which cooling solution could flow. Our results demonstrated a reduction in temperature of the order of 3 degrees C around the tube when coolant was flowing, and the cooling pattern correlated with theoretical mathematical predictions. Up to 564 joules per minute could be removed from the system. Our results suggest the improbability of uniform tumor cell killing by RF heating. A scheme for integrating the concepts of physical cell damage, biochemical cell damage and peripheral cell survival in a tumor nodule is presented.

Chemotherapy, Cancer, Regional Perfusion↗

An unusual radiological artefact: a nipple ring.

An article of adornment, a metallic ring through the nipple, was noted on plain chest radiographs of a 25-year-old man. Depending on the geographic location, the laterality of the nipple ring might alert the radiologist to the possibility of homosexuality and the potential diagnosis of AIDS in the radiographs.

Adult↗