Assessment was made of the fibrinolytic activity in menstrual and peripheral blood of 30 normally menstruating and 30 menorrhagic patients and of 30 women wearing Lippes Loops and 15 wearing CU-T (200)s. Assessment was performed by measuring the area of lysis on heated and unheated fibrin plates. Also, histochemical identification of fibrin fibrils in the menstrual endometrium was performed by Mallory's phosphotungstic acid hematoxylin method. Results in the normally menstruating group were compared to those of the menorrhagic women, and together these were compared with results in the groups of women wearing intrauterine devices. The fibrinolytic activity in menstrual blood was significantly increased in menorrhagic patients compared to that in normally menstruating patients, but no significant difference was detected in the plasma of either group. The histochemical study of the normally menstruating endometrium revealed dense intravascular and extravascular deposits of fibrin. Less dense intravascular fibrin deposits, but no extravascular ones, were present in the menorrhagic patients. The increase in the fibrinolytic activity of menstrual blood and the decrease in the density of fibrin deposits in the menstrual endometrium of the menorrhagic women were thus associated and were probably involved in the excessive menstrual loss. The fibrinolytic activity of menstrual blood in women wearing Lippes Loops was higher than that in women with Cu-T (200)s and was associated with decreased density of fibrin fibrils in the menstruating endometrium. This may explain the increased blood loss associated with the use of the Lippes Loop.

Adolescent↗

PubMedDate not supplied

Physiologic studies of menstrual blood loss. I. Range and consistency of menstrual blood loss in and iron requirements of menstruating Egyptian women.

Two physiologic studies of menstrual blood loss in Egyptian women are presented below. In the first, an attempt was made to establish the normal range of menstrual blood loss of Egyptian women, to test their individual consistency in the amount of menstrual blood loss and to determine the iron requirements needed to compensate for iron loss and prevent iron deficiency anemia in menstruating Egyptian women. In the second, physiologic and other variables affecting the magnitude of menstrual blood loss in Egyptian women were investigated.

Adolescent↗

PubMedDate not supplied

A simple technic of hysterography for evaluating side effects and mode of action of intrauterine devices. A study of 100 cases.

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Colic↗

PubMedDate not supplied

Physiologic studies of menstrual blood loss. II. Physiologic variables affecting the magnitude of menstrual blood loss.

The effect of marital status, age, parity, age at menarche, maternal size, arterial blood pressure, position and size of the uterus and hematologic parameters on the magnitude of menstrual blood loss was investigated in 745 randomly selected women in normal physiologic condition, aged 14-49 years, from a city population (Cairo). Menstrual blood loss was found to be related to parity, weight and body surface area and systolic and pulse pressure and to depend mainly upon the hematologic indices reflecting the state of iron balance and anemia in the body.

Adolescent↗

PubMedDate not supplied

Contraception during lactation.

Seven hundred and seventy-two lactating mothers were studied from delivery for 1 year to select the best contraceptive method (oral drug, injected drug, or IUD) which did not affect lactation. Ten groups of mothers were studied, including 234 control subjects. The injectable progestational contraceptives caused an improvement in the amount of milk and its protein concentration, whereas the IUCDs did not influence the lactation pattern. Sulpiride was an ineffective contraceptive but a potent lactation stimulant. The side effects of each method (effects on milk yield, protein content and prolactin concentrations) were also noted; it was concluded that IUCDs are the ideal contraceptive method during lactation, with the use of a lactation stimulant when indicated.

Algestone↗