Biomedical subjects
Publications and source records attributed to F Hagen.
The exceptional coincidence of puerperal ovarian-vein-thrombosis and a pregnancy with quadruplets is reported. The importance of confirming the diagnosis by non-invasive methods (CT) in cases showing atypical clinical pictures and the significant incorrect diagnoses are described.
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We have located an extensive (AC)n-rich but specific sequence downstream of three rainbow trout protamine genes. Although sharing considerable sequence homology, including a perfectly conserved 46 base pair repeat, the sequences exhibit a regular heterogeneity in the length of the (AC)n-rich tracts. Radioimmunoassay experiments, S1 nuclease sensitivity studies, two-dimensional electrophoretic analysis, and immunoelectron microscopy studies have been used to determine if the region could assume a Z DNA conformation. It was found that, in a supercoiled plasmid, the (AC)n-rich region has the ability to attain the Z DNA conformation under physiological conditions.