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Biomedical subjects

F Guiot

Publications and source records attributed to F Guiot.

5 recordsLinked to original sources

[A case of Enterobius vermicularis salpingitis].

Enterobius vermicularis peritonitis due to intestinal infection is a common entity described in the literature. We report here an unusual case of unilateral salpingitis associated with the parasite migration through the genital tract.

Adult↗

Isolated familial adrenocorticotropin deficiency: prenatal diagnosis by maternal plasma estriol assay.

We report on a brother and sister with adrenal insufficiency due to isolated adrenocorticotropin hormone deficiency discovered in the neonatal period. The first-born, a male infant, died; pathological findings suggested bilateral adrenal hypoplasia transmitted as an autosomal recessive trait. Plasma estriol levels were assayed during the mother's next pregnancy. The prenatal diagnosis allowed immediate and effective management of the second affected child. The supplementary evidence from the endocrine findings, unavailable on her brother, enabled us to make a diagnosis of isolated central ACTH deficiency. As the defect was found in infants of both sexes in the same family, it is in all likelihood transmitted as an autosomal recessive trait. We consider it important for genetic counselling to perform autopsies on all newborn infants whose death has no apparent cause. Maternal plasma estriol assays during pregnancy can help diagnose fetal adrenal insufficiency, whether the defect is central or adrenal.

Adrenal Insufficiency↗

Negative effects of chronic hemicerebellectomy of epileptiform after-discharges elicited by focal cortical stimulation in baboons (Papio papio).

The influence of chronic hemicerebellectomy on cortical epileptiform after-discharge (AD) induced by focal electrical stimulation was studied in the baboon. These preliminary results include 22 ADs elicited from motor cortex and 22 ADs elicited from premotor cortex before and after hemicerebellectomy. Only full-developed, generalized seizures with postictal silence were considered. EEG morphology, average duration and average current threshold were compared for each set of ictal events. No significant differences were found before and after hemicerebellectomy.

Animals↗