Search PubMedSearch

Biomedical subjects

F Guilbert

Publications and source records attributed to F Guilbert.

At least 19 recordsLinked to original sources

[Mandibular fractures. Our patient enrollment during the past 2 years].

The method of patient referral; the patient's physical predisposition, the localization and the treatment undertaken for the different mandibular fractures seen by SOS Face over the past two years were analyzed. The 312 mandibular fractures were used to reevaluate the commonly accepted statistics concerning these parameters.

Adolescent

[The maxillofacial surgeon faced with the HIV-positive patient: risks and prevention].

Prevention against the transmission of the HIV must be universal today, which means that it applies to all patients. Blood, tissues, the CSF are infected, but nasal secreta, tears and saliva are not contaminated unless they contain blood. The statistical risk of an HIV serological conversion when making an injection is an estimate of 0.1 to 0.3%, one hundred times less than with the hepatitis B virus. The best protection for maxillofacial surgeons, who are very exposed by the manipulation of objects (needle, wires) and by considerable projections of blood (rotary motor) is not a systematic HIV serological test for all patients, but goggles with side screens, a double pair of gloves and the use of an antiseptic acting on the HIV in case of staining.

Acquired Immunodeficiency Syndrome

[An unusual form of primary epithelioma of the mandible: odontogenic clear cell carcinoma. Clinical and morphologic study].

One case of aggressive intramandibular epithelial tumor is presented. This tumor demonstrated an unusual pattern with areas of follicular ameloblastoma together with undifferentiated trabeculae or lobules composed of basophilic cells and of clear glycogenic-rich cells. The odontogenic nature of this tumour and its analogies with common ameloblastoma were demonstrated by electron microscopy, immunohistoenzymology and immunohistochemistry. The signification of such a neoplasm is discussed.

Adenocarcinoma

Acinic cell carcinomas of salivary glands histoprognosis. Value of NORs stained with AgNOR technique and examined with semi-automatic image analysis.

Twenty one patients surgically treated for acinar cell salivary gland carcinomas were studied retrospectively. Four cases were excluded from the results because of an inadequate follow-up time (less than 5 years). The rest was classified into two groups: eleven patients with a favorable outcome were still alive without any recurrence after a mean follow-up period greater than 10 years; in six other patients, recurrences and metastases occurred followed by death in four cases. Previously for such tumors a high degree of histological undifferentiation usually gave rise to a poor prognosis, although some exceptions were noted. Thus, in an attempt to find a more reliable prognosis criterion, we evaluated by semi-quantitative image analysis nucleolar organizer regions by means of AgNOR count and mean area in all these cases. Our results significantly correlated with the clinical prognosis: a high count (more than 3) and a small mean area were always found in tumors with an unfavorable outcome whereas lower counts and larger mean areas were found in tumors with a favourable clinical course. Thus, this method showed promise as establishing the prognosis of acinar cell tumours.

Adult

[Metastases of malignant tumor in the jaw. Analysis of 30 case reports].

30 metastases of malignant tumors in jaws were retrospectively studied. They occurred more often in women than in men (17 F/13 H). In 21 cases, the primitive cancer was known and had been treated 1 to 4 years before. In the other cases (9), the bone metastasis led to the discovery of a latent tumor. Clinical signs and symptoms included swelling, pain, loosening of teeth, labio-mental anaesthesia and rarely pathologic fracture. Radiologically, all but two patients had radiolucent lesion. These metastases almost always involved the mandible (95% of cases) and in that bone, most often molar area and angle. Histologically, the majority of lesions were adenocarcinomas from breast (33%) and alimentary canal (stomach, colon). Epidermoid bronchial carcinomas were seen in 5 cases and malignant melanomas in 2 cases. Only one sarcoma of this series was arising from a liposarcoma of the thigh. In all but one patients, evolution was quickly lethal.

Adult

[Dental implantology and expertise. Apropos of 6 cases].

Dental implants are used with increasing interest each day. This costly material, which is reimbursed neither by Public Social Protection Agencies nor by private health insurance companies, has become a cause for lawsuits. We analyzed the experts' conclusions regarding legal mementos and expert reports, wherein medical liability (4 cases) and repair of dental injury (2 cases) were put into question. The experts stress the need to regard this technique as surgical, and to have it necessarily yield results. Repair of damage caused by dental trauma using implants does not alter conventional approaches in terms of social security cover for maintenance and replacement of dental prosthesis. Difficulties encountered by experts in evaluating injuries sustained by bone-adapted implants are evoked.

Dental Implantation, Endosseous

[Congenital microphthalmos. Orbital and palpebral expansion].

Ocular atrophy in prime infancy leads to lack of orbital growth. Current treatment of plastic surgery in severe deformities is unsatisfactory, whereas tissue expanding techniques using intraorbital balloon are effective on orbital cavity growth. This procedure makes use of conjunctival shells or aesthetic ocular prosthesis easier, and allows an improved reconstruction. Description of implants and surgical technique of insertion used.

Child

[Extra-nodal lymphoma of the cervicofacial region: anatomo-pathological aspects].

The B lymphomas formed the great majority (greater than 90%) of lymphomas in a series of 80 extra-nodal lymphomas of the cervico-facial region, all categorised by immuno-histochemistry. They also tended to be tumours of the highly malignant type (61%): lymphoblastic, immunoblastic, centroblastic and Burkitt's lymphomas.

Facial Neoplasms

[Malignant maxillofacial extra-nodal lymphoma].

64 patients with extra-nodal maxillo-facial NHL were seen between 1969 and 1989. These rare tumours (1 to 4% of stomatological tumours) tended to occur more often in men (60% of cases) between the ages of 40 and 70. Bony involvement was common (maxillary and mandibular involvement), though more rarely the salivary glands or mucosa were involved, presenting as a swelling with lysis of underlying bone. Highly malignant varieties (85% of cases) were most commonly encountered. The treatment remains medical, involving chemotherapy (C.H.O.P. or high dose methotrexate) and gives an actuarial survival rate of 50% at 3 years.

Adult

[Lymphoma of the salivary glands. New nosologic frontiers].

The classification of salivary lymphomas, including the ambiguous Mikulicz syndrome, has been considerably modified in recent years thanks to advances in immuno-histochemistry. Following the distinction between pseudo-lymphoma and true lymphoma, made possible by the latter, the situation has now become less clear due to the existence of possible transition between the two entities. Moreover, the increasing identification of a particular form of lymphoma involving the salivary glands in Sjogren's syndrome (MALT type lymphoma - centrocytic-like) analogous to that seen in the gastrointestinal tract, now opens up the possibility of very early diagnosis of these tumours. However, the significance in terms of treatment of this monoclonal variant as a tumour criterion still remains difficult to define.

Diagnosis, Differential

[Benign paralysis of the 6th cranial nerve in children].

Acquired sixth nerve palsies in infants and children that occur without fever primarily suggest a tumor or intracranial hypertension. In a few instances, the cause is benign and spontaneous recovery occurs although relapses are occasionally seen. We report seven episodes of benign sixth nerve palsy in four children aged 5 1/2 months to 8 1/2 years. An ENT infection was the precipitating factor in four of these seven episodes. Recovery consistently occurred within 4 days to 6 weeks. None of the children had residual oculomotor impairment. The various etiologic hypotheses put forward in the literature are discussed. No study provides a pathophysiologic explanation for these transient palsies.

Abducens Nerve

[Metastasis of a malignant melanoma simulating a primary mandibular sarcoma].

The rare case reported here was a mandibular metastasis of a malignant melanoma located in the nape of the neck and surgically removed. 4 years later, occurred a fibrosarcomatous mandibular tumour without local recurrence. The metastatic nature of this tumour was difficult to prove by means of immunohistochemical and ultrastructural methods. This case illustrated the eventuality of a desmoplastic change in metastasis of a common malignant melanoma. The histogenesis of this rare type of melanoma was discussed.

Diagnosis, Differential