Biomedical subjects
Publications and source records attributed to F Grimalt.
There are various references to sensitization to beryllium in the literature. Since introducing a patch testing series for patients with suspected sensitization to metals, we have found 3 cases of sensitization to beryllium. Of these 3 cases, we regard the first 2 as having relevant sensitization. Beryllium chloride (1% pet.) was positive in 3 patients and negative in 150 controls.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A case of contract sensitization to the ethylene oxide by a mask sterilized with this substance is reported. The mask was correctly sterilized but the ethylene oxide was not completely evaporised. The path tests were positive in the patient but negative in 25 control subjects. The patch tests with the international series and with all the elements of the mask were negative. The possible troubles of ethylene oxide and the sterylisation methodes of this substance are reviewed.
An hitherto undescribed type of contact dermatitis in a series of 16 patients is described by the authors. The lesions were localized in the anterior and anterolateral aspects of the thighs and were sharply limited in the area contacting the trouser pockets, manufactured with synthetic fabrics. In 17 patients of this series there was a concomitant dermatitis in the exposed areas of the face and hands. The authors described the processing in the manufacture of these pockets, the end step being the obtention of poliamide, through different precursor substances. The poliamide is treated with different aditives giving rise to the nylon fiber, which is used to manufacture the definitive tissue. A list of adequate allergens and their concentrations used in the 16 patients is given in the paper. The results of the patch tests and the fact that all the clinical symptoms of the patients disappeared after the withdrawal of the tissue pockets and substitution by cotton tissue give a reasonable basis to the hypothesis of contact dermatitis caused by this tissue. However, the true specific allergen is not demonstrated yet.
Changes in the shoe industry have replaced some of the former allergens and introduced some new ones. In 45 cases of shoe contact dermatitis, the lack of response to known allergens inspired the authors to review present-day industrial shoe manufacture. Two new resin allergens for shoe dermatitis have been found: dodecyl mercapthane and polyurethanes. The first is used in the plastics industry to arrest the polymerization process. We suggest the possibility that a certain number of Neoprene sensitizations could be sensitizations to dodecyl mercapthane contained in it. The recommended solution for patch testing is: 0.1% in toluol.
Explore the source record for details and available documents.
Explore the source record for details and available documents.