[Hemorrhages of the area of the terminal vein in the premature infant and their importance in the incomplete development of the venous wall in their etiology].
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Basal Ganglia↗
Biomedical subjects
F Gori
Publications and source records attributed to F Gori.
[Xanthogranuloma of the retroperitoneal space].
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Adult↗
Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development.
Fibromodulin, a keratan-sulfate proteoglycan, was first isolated in articular cartilage and tendons. We have identified fibromodulin as a gene regulated during BMP-2-induced differentiation of a mouse prechondroblastic cell line. Because expression of fibromodulin during endochondral bone formation has not been studied, we examined whether selected cells of the chondrocytic and osteoblastic lineage expressed fibromodulin. Fibromodulin mRNA was detected in conditionally immortalized murine bone marrow stromal cells, osteoblasts, and growth plate chondrocytes, as well as in primary murine calvarial osteoblasts. We, therefore, investigated the temporo-spatial expression of fibromodulin in vivo during endochondral bone formation by in situ hybridization. Fibromodulin was first detected at 15.5 days post coitus (dpc) in the perichondrium and proliferating chondrocytes. Fibromodulin mRNA was also detected at 15.5 dpc in the bone collar and periosteum. At later time points fibromodulin was expressed in the primary spongiosa and the endosteum. To determine whether fibromodulin was expressed during intramembranous bone formation as well, in situ hybridization was performed on calvariae. Fibromodulin mRNA was present in calvarial osteoblasts from 15.5 dpc. These results demonstrate that fibromodulin is developmentally expressed in cartilage and bone cells during endochondral and intramembranous ossification. These findings suggest that this extracellular matrix protein plays a role in both endochondral and intramembranous bone formation.
Animals↗
A dipole-type intracavitary hyperthermic applicator with a metallic reflector: experiments and theoretical analysis.
A water-cooled electromagnetic (EM) dipole, for intracavitary hyperthermia, embodying a metallic reflector to give directional characteristics to the SAR and then to the heating pattern in the biological tissue, is considered. The influence of the reflector on the SAR deposition has been theoretically modelled with an EM analysis which uses the method of moments (MOM). A thermal model, based on the heat transfer equation, is used to predict temperature distribution, which exhibits a directivity related to the angular extension of the reflector. Experiments have been carried out in a polyacrylamide phantom. The temperature distribution detected with a liquid crystal sheet shows fairly good agreement with theoretical predictions.
Electromagnetic Phenomena↗
[Nurses' professional responsibility].
As managed care relevance is growing, several old issues related to personal institutional responsibility are increasing among practitioners. Therefore, as a professional figure a nurse bases his/her job on a mix of personal knowledge and skills along with training, and he/she is responsible for giving advice in line with professional care standards. In addition, he/she is in charge of the treatment pattern agreed with the patient. However, nursing is a much more complex job, which leads professional figures facing the controversial issue of combining institutional responsibility and nursing professional tasks and duties daily. As far as nursing institutional responsibility is concerned, different view points or approaches can be applied to investigate it. The most common one is the legal approach, yet this is not the most appropriate one. Therefore, our professional background is mainly based on a management prospective rather than a legal one; dealing with the issue legally would lead, essentially, to a summary of laws and regulations without any kind of argumentative discussion. Consequently, this study aimed to analyze nurses' institutional responsibility by approaching the issue from an innovative human resources management prospective; therefore, defining the gap between nursing institutional responsibility and its tasks.
Italy↗
Wdr5, a novel WD repeat protein, regulates osteoblast and chondrocyte differentiation in vivo.
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Animals↗
[Intra-arterial diazepam. Treatment and evolution of a case].
The Authors report a case of accidental self-administration of diazepam (valium) in the brachial artery by a drug addict and describe the developments, the sequelae and the pathogenetic mechanism.
Accidents↗
[Histologic analysis of intraepidermal melanocytic proliferation in the peripheral area of superficially diffused melanoma].
Histological analysis of intraepidermal melanocytic proliferation in the peripheral areas of superficial spreading melanoma. The intraepidermal melanocytic proliferation in the areas adjacent to the invasive component of 100 superficial spreading melanomas of the skin (levels III and IV) was studied. Three patterns were identified: 1) melanoma in situ type (MIS); 2) melanocytic dysplasia type (DYS); 3) normal skin or increased number of typical melanocytes (0). The different distribution of these patterns in the areas adjacent to the invasive melanoma led to a histological classification of the tumors into 4 topographical models. Two models showed MIS areas and contiguous normal skin (A1, A2); two models showed MIS areas adjacent to DYS areas, that in turn were contiguous to normal skin (B1, B2). In all cases, however, in centrifugal sense, more severe alterations preceded less severe ones. These observations suggest that superficial spreading melanoma grows horizontally by induction of neighbour cells (neoplastic recruitment). The neoplastic transformation seems to progress in two ways: directly to melanoma in situ or through an intermediate phase (melanocytic dysplasia).
Cell Division↗
[Propofol versus thiopentone. A hemodynamic study].
The authors, after a brief introduction concerning the importance of the use of NCCOM3 (Non invasive Continuous Cardiac Output Monitor) for the non invasive assessment of the haemodynamic parameters (Cardiac Output, Heart Rate, Ventricular Ejection Time, Stroke Volume), compare the haemodynamic variations induced by two types of intravenous anesthesia in 40 patients, selected at random, who underwent anesthesia for minor gynaecological procedures in the day hospital. The results obtained show that the haemodynamic variations induced by thiopentone and propofol are almost analogues until the end of surgery, while a difference, even though statistically non significant, was observed at the moment of reawakening. The authors would like to underline the synergism of two drugs and fentanyl as regards to the depressive effects on blood circulation.
Adult↗
[Giant cell arteritis, synonym of Horton disease?].
Giant cell arteritis: a synonym of Horton's disease? Biopsies from the temporal artery of 50 patients with Horton disease were evaluated retrospectively by light microscopy and immunohistochemical methods. All patients were adults over 60 years: 28 female, 22 male. Histopathologic study of the biopsies disclosed four main variants most likely related to different stages of temporal arteritis. Only in 22 cases the typical granulomatous giant-cell pattern was observed. However similar pathologic findings occur in several other chronic vasculitis, granulomatous giant cell inflammation being a mark of an advanced stage of the disease rather than a mark of a specific type of arteritis. Therefore < > and < > cannot be considered synonymous, contrary to what usually happens in clinical practice.
Aged↗