Biomedical subjects
Publications and source records attributed to F Goldberg.
The cleanliness of the root canal space depends more upon the root canal morphology than on the technique used for preparation. Sonic and ultrasonic devices can be useful systems to help facilitate several steps in endodontic therapy. These are: instrumentation of the coronal and middle thirds, instrumentation of ribbon-shaped canals, removal of foreign obstructions and obturation of the root canal space.
In this study we performed an in vitro assay of the effects of two gutta-percha formulations and one zinc oxide-eugenol and Canada balsam-based endodontic material on the behavior of a mixed cell population of human monocytes and lymphocytes. Cells were cultured either in direct contact with or near experimental samples of Ultrafil, standard gutta-percha cones or Endoseal and the inhibitory effects of these materials upon cell attachment and spreading on test surfaces were analyzed. Ultrafil and the standard gutta-percha cones showed little or no adverse effects, whereas the inhibitory effects of Endoseal appeared to be severe. There were statistically significant differences between the results obtained from both Ultrafil and gutta-percha cones and those obtained from Endoseal. Differences between all tested materials and their respective controls were also statistically significant.
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Scanning electron microscopy was used in an in vitro evaluation of EDTAC's effect on the dentinal wall of the root canal. The effects produced by varying its working time were observed. This analysis was done on twenty-four sections of roots in longitudinal and transversal cuts. After 5 minutes a certain cleansing effect on the dentinal wall as compared with the control was observed. the strongest effect was detected at 15 minutes, with no variations after 30 minutes.
A multicenter double-blind study of 363 pediatric outpatients with acute otitis media demonstrated that cyclacillin, administered in three divided doses (three times a day) for ten days, is as effective as and better tolerated than a similar regimen of amoxicillin. The bacteriologic cure rate for patients with middle-ear cultures was 98% in both treatment groups. Remission of signs and symptoms was significantly faster in the cyclacillin group (3.1 days) than in the amoxicillin group (4.3 days) (P less than 0.05). Of the 179 children treated with cyclacillin, three (1.7%) had drug-related diarrhea in contrast to 18 of the 184 (9.8%) children treated with amoxicillin (P less than 0.01). Cyclacillin produces a rapid resolution of symptoms and a low incidence of diarrhea.