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Biomedical subjects

F Gold

Publications and source records attributed to F Gold.

At least 91 records · Page 5Linked to original sources
PubMed1987

[Cardiac and cerebral involvement in aneurysms of the ampulla of Galen. Contribution of echography and cerebral Doppler flowmeter in the neonatal period].

An arteriovenous malformation of the vein of Galen was diagnosed using two-dimensional ultrasound and pulsed Doppler method, in a neonate with congestive heart failure. Contrast echocardiography showed right to left atrial and ductal shunting. Sector scans of the brain revealed an echo free intracranial mass with venous flow at the Doppler. Doppler assessment of the main cerebral arteries was also performed. In neonates presenting with severe congestive heart failure of unknown etiology, two-dimensional ultrasonography provides an accurate and rapid diagnosis of a cerebral arteriovenous malformation with aneurysm of the vein of Galen. Ultrasound method may also contribute to improve the comprehension of the physiopathology underlying the clinical findings.

Cerebral Veins↗
PubMed1987

[Effect of aztreonam on the fecal aerobic flora in children].

Aztreonam, a new monobactam, has a spectrum limited to Gram negative aerobic bacilli. To evaluate its effect after parenteral administration on aerobic stool flora (Gram negative bacilli, Streptococci D, Staphylococci, Candida), quantitative cultures used serial dilution of stools twice a week on selective media. For Gram negative bacilli, agar dishes containing aztreonam or not were used. Colonies of different morphologies were counted. Representatives of each morphological type were then picked for identification and susceptibility tests. Among the 16 patients treated, 12 were decontaminated for aerobic gram negative bacilli by the 3rd day. Sensitive bacteria persisted in 4 cases, although at a low level. Resistant bacteria (Enterobacter cloacae and Acinetobacter) appeared at a "normal" level in 2 patients initially decontaminated. No dramatic change could be detected for Streptococci D, Staphylococci and Candida. In twelve additional infants neither hospitalized nor treated, no aztreonam resistant Gram negative bacilli could be found.

Adolescent↗
PubMed1986

Choanal atresia and deafness.

Nine cases of bilateral choanal atresia are reported. The association with other malformations and deafness is evaluated. The choanal atresia is associated with multiple malformation in two cases and bilateral deafness in 5 cases. Before discussing surgery, a complete evaluation has to be performed, deafness has to be evaluated with modern electrophysiological methods. The risks of the surgery should be considered in case of cardiac malformation and cerebral anoxia.

Abnormalities, Multiple↗
PubMed1986

The effect of imipenem/cilastatin on the aerobic faecal flora of children.

In 18 children treated with imipenem iv, quantitative cultures for aerobic faecal flora were performed on selective media (before, when possible, during and after treatment). In ten children who had not received previous antibiotic therapy, susceptible enterobacteria could be detected at a normal level throughout treatment. Eight children had received other antibiotics beforehand; during the first week of imipenem therapy, enterobacteria were undetectable in two and at low levels in three patients. In one patient previously treated with aztreonam, a strain of Pseudomonas aeruginosa became resistant to imipenem and increased in numbers. No dramatic change could be detected in group D streptococci, staphylococci or candida. The surprisingly small effect of imipenem on faecal Enterobacteriaceae could be explained by its inconstant presence in stools at the dose administered.

Adolescent↗
PubMed1985

[Non invasive measurement of the cerebral blood flow in infants with hydrocephalus].

The present study was undertaken to verify by a non invasive Doppler technique the effect of ventricular dilatation on cerebral blood flow in infants with hydrocephalus. The measurement of pulsatile flow in cerebral arteries is also a valuable parameter for determination of optimal timing of corrective intervention.

Cerebrovascular Circulation↗
PubMed1985

[Echographic monitoring of post-hemorrhagic ventricular dilatations in premature newborn infants. Value of the determination of a ventricular index].

The target of this work was the determination of a quantifiable measurement of the ventricular dilatation with an index during the ultrasonographic supervision of intraventricular hemorrhages (IVH) in premature infants. An investigation by cerebral ultrasonography through the fontanelles was performed in 63 non hypotrophic prematures. Thirty-one children (mean gestational age 32 +/- 1.8 weeks) had an IVH. All had ventricular dilatation at one time during evolution. The 32 other children (mean gestational age 34 +/- 2 weeks) showed normal ultrasonographic data and a ventricular index between 0.15 and 0.25 (mean 0.23 +/- 0.02). Post-hemorrhagic ventricular dilatation can be classified into 3 stages: slight dilatation: ventricular index between 0.26 and 0.30; moderate dilatation: ventricular index between 0.31 and 0.40; severe dilatation: ventricular index greater than 0.40. The use of a ventricular index allows precise following of the ventricular dilatation during the supervision of intraventricular hemorrhages.

Cerebral Hemorrhage↗
PubMed1983

[Prevention of contamination of microhemocultures. Value of a new instrument, the hemopipette].

We have experimented with a new instrument, "hemopipette", known to reduce the incidence of contamination in small samples of capillary blood for haemoculture. Without altering our usual skin asepsis procedure, we carried out 270 microhaemocultures in 240 neonates. Two haemocultures (0.74%) were contaminated, a significantly lower percentage than the 3.6% observed in a first series of 411 microsamples obtained prior to the introduction of "hemopipette". This fall in contamination rate appears to be associated with the use of this instrument which combines a pipette and a lancet and facilitates capillary blood withdrawal.

Blood Specimen Collection↗
PubMed1982

Favorable effects of acebutolol on exercise performance and angina in men with coronary artery disease.

Acebutolol, a relatively cardioselective beta-adrenergic blocking drug, was administered to 20 men with coronary artery disease and angina. A three month double-blind cross-over (placebo and acebutolol) design was used following a 12-week placebo phase and a six-week dose-titration phase. During the cross-over phase, acebutolol (400 mg in 19 men and 300 mg in one, orally three times per day) increased the duration of treadmill exercise (placebo, 6.8 +/- 0.5) min [average +/- SEM]; acebutolol, 8.1 +/- 0.6 min; P less than 0.05) and decreased the frequency of ST segment depression during exercise (placebo, 12 or 20 men; acebutolol, 6 of 20 men). The heart rate x systolic blood pressure product (x 10(-2)) was decreased both at rest (placebo, 105.0 +/- 4.0; acebutolol, 84.0 +/- 3.0; P less than 0.01) and during exercise (placebo, 199.0 +/- 10.0; acebutolol, 144.0 +/- 8.0; P less than 0.01). Acebutolol treatment decreased the frequency of angina (diary cards) (placebo, 9.0 +/- 2.4 episodes per week; acebutolol, 6.4 +/- 2.2 episodes per week; P less than 0.05) and decreased the consumption of nitroglycerin (placebo, 9.0 +/- 4.4 tablets per week; acebutolol, 7.4 +/- 4.0 tablets per week; P less than 0.05). Results suggest that acebutolol increases exercise performance and decreases the occurrence of angina in men with coronary disease.

Acebutolol↗
PubMed1982

[Gastro-intestinal disorders in premature neonates receiving early enteral feeding (author's transl)].

Gastro-intestinal (G-I) disorders were studied in 95 premature neonates. Each child presented with at least one of the features usually associated with mesenteric ischemia. Nearly all the children had been fed early with tyndallized maternal milk. No certain necrotizing enterocolitis (NEC) was observed; however, it was suspected in 4 children (4.2%) and in 7 (7.3%), minor changed occurred. Among the 13 factors examined which might be responsible for inducing NEC, only 2 were correlated with G-I disorders: low birth weight (less than 1,500 gm) and occurrence of secondary apnea or asphyxia incidents during mechanical ventilation. This study led to the following practical conclusion: maintenance of early enteral feeding in prematures theoretically at risk for G-I disorders, taking into account the low incidence of severe G-I impairments and of the advantages of such a feeding method, while carefully supervising intestinal symptoms; preventative and temporary interruption of feeding in low weight prematures, in case of acute asphyxia or hypoxia episodes.

Asphyxia Neonatorum↗