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Biomedical subjects

F Gioia

Publications and source records attributed to F Gioia.

6 recordsLinked to original sources

[IgD myeloma: an aggressive variant. Description of a clinical case and review of the literature].

It is shown a case of IgD myeloma, a rare type of myeloma having often an aggressive course. Besides to confirm clinical and laboratory aspects already known in literature, this case seems to make in evidence a rapid neoplastic proliferation kinetic, difficult to be controlled by conventional chemotherapy. The Authors show that the M component low concentration and the unbalance of the synthesis of the immunoglobulin heavy and light chains may confuse IgD myeloma with light chain myeloma.

Aged↗

Interaction between high frequency jet ventilation and cardiovascular function.

We have studied the interaction of high frequency jet ventilation with cardiovascular pressures and flows. Results in dogs show that the amplitude of all intrathoracic pressures and flows fluctuate with a frequency equal to the difference between the heart rate and ventilator rate. The magnitude of this amplitude variation may be sufficient to obliterate periodically the pulsations in pulmonary artery and right atrial pressures. It is also shown that these cardiovascular beats can occur when the ventilator rate is close to integral multiples of the heart rate. Direct measurement of pleural pressure and the observation that the beats are markedly reduced when the chest is open support the hypothesis that the primary mechanism responsible for these beats is the interaction of the respiratory fluctuations in pleural pressure with the cardiac-generated pressure pulsations.

Animals↗