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Biomedical subjects

F Galietti

Publications and source records attributed to F Galietti.

At least 37 records · Page 2Linked to original sources

[Comparison of the bronchodilating activity of procaterol and nicardipine in chronic forms of bronchial asthma].

The bronchodilatory activity of one beta 2-stimulation (procaterol) and one calcium antagonist (nicardipine) both recently introduced was compared in a group of chronic asthmatics in the clinical remission phase. The experiment took the form of the randomised double blind administration of procaterol or nicardipine or a placebo twice a day for 15 days with spirometric tests being performed before, during and after the experiment. The results show that nicardipine does have a bronchodilatory effect though less than the beta 2-stimulant.

Adult↗

[Data on cellular subpopulations in bronchoalveolar lavage in silicosis and asbestosis patients. Case contribution].

Data on the cytology of BAL performed on 8 silicosis and 5 asbestosis patients with different degrees of radiological profusion and functional impairment are examined. The prevalently neutrophilic alveolitis reported in the literature in these forms of pneumoconiosis is confirmed, while differences were found between the percentage of lymphocyte subpopulations in the two diseases.

Aged↗

[Scintigraphic findings with a positive marker in generalized lymphadenopathy syndrome (L.A.S.)].

The behaviour of gallium scintigraphy in a group of 15 drug addicts suffering from LAS is examined. The examination was positive in 11 patients with no pleuro-pulmonary lesions that could be demonstrated by clinical or radiological examination. This is in line with similar observations in AIDS cases and may reflect the preactivation of monocytes and macrophages documented in HIV infection.

AIDS-Related Complex↗

[Use of miocamycin in the acute exacerbation of chronic obstructive bronchopneumopathy. Case material contribution].

18 patients with chronic obstructive bronchitis were treated with 900 mg myomycin a day. The clinical parameters examined were the quantity and organoleptic characteristics of the expectoration, coughing, and body temperature. These parameters were studied immediately before and 7.14 and 21 days after the start of treatment. Myomycin was found to be satisfactorily effective with minimal toxicity and well tolerated.

Aged↗

[Radioscintigraphic correlation in interstitial pneumopathy. Case presentations].

Radiological and scintigraphic findings in 82 patients (58 male, 24 female) were compared. The patients were hospitalised in 1981-86 with sarcoidosis (43 cases), silicosis (26), asbestosis (9) extrinsic allergic alveolitis (3), lung disease caused by hard metals (1). Gallium scintigraphy was positive in 61 patients (74.39%). More precisely, the response was positive in 57 cases in both analogic and quantitative terms and in 4 only quantitatively. The radiological (radiography and stratigraphy) finding was significant in 42 of the 61 gallium-positive cases and negative in the remaining 19. In the 21 gallium-negative cases (25.61%) the radiological finding was significant in 9, negative in 12. The study confirms the real value of gallium scintigraphy in the diagnosis and follow-up of interstitial lung disease in line with views presented in the recent literature.

Adult↗

[Clinico-pathological aspects of farmer's lung. Review of the literature and personal cases].

Data are presented on 9 subjects with Farmer's lung encountered in 1981-85. In all cases dyspnea arose within several hours after exposure to the allergen and in 4 cases only a few minutes after exposure. The radiological picture was altered in 7 cases (6 miliary pictures and 1 case of medial and basal nodulation). In functional terms 6 restrictive and 3 mixed forms were identified. The specific bronchial provocation test was positive wherever it was performed. Bronchoalveolar lavage revealed predominantly lymphocytic alveolitis in the most recent cases. Transbronchial biopsy also revealed the presence of pulmonary granulomatosis in various stages of development. Finally skin tests were positive to various antigens in several cases while specific precipitin were found in all cases. These data are compared with reports in the literature.

Adult↗

[Pathological and clinical aspects of bronchial carcinoid tumor. The authors' own case reports].

Data (radiological, endoscopic, histological, clinical and surgical) are presented on 21 subjects with pulmonary carcinoid tumour encountered in the Turin University Chest Surgery Centre in 1980-1985. All patients were subjected to fibrobronchoscopy which revealed the tumour in 18 cases (14 were given multiple biopsies and in 4 cases samples could not be taken due to the patient's intolerance of the endoscopic manoeuvre). No appreciable bleeding occurred after any biopsy. Surgery was performed on all 21 patients (2 pneumonectomies, 7 bilobectomies, 12 lobectomies). There was 85.71% correspondence between pre and post-operative histological diagnosis.

Adult↗

[Potential use of indenolol in hypertensive patients with chronic bronchial asthma].

The data are reported on a double blind clinical experiment using indenolol on a group of asthmatic hypertensives. The drug revealed a satisfactory anti-hypertensive action in the absence of any significantly bronchoconstrictive effect. The orciprenaline test performed at the end of the experiment showed that the drug does not reduce the availability of beta 2 bronchial receptors vis-à-vis the beta 2 stimulants.

Aged↗

[Efficacy of the simultaneous aerosol administration of fenoterol and 2(alpha-thenoylthio)propionylglycine].

The aim of the present study was to investigate the effect of a new mucolytic drug 2-alpha-tenoiltium-propionylglycine (2-alpha-TPG) administered in spray form together with a selective beta 2 stimulant, fenoterol. A double blind test was conducted on 26 patients to whom 2-alpha-TPG-fenoterol and placebo-fenoterol were given in spray form in two daily doses for 15 days at 10 day intervals. The data suggest the existence of an additive effect between the mucolytic drug (2-alpha-TPG) and the beta 2 stimulant (fenoterol) that would justify the use of the combination in the treatment of such patients.

Aerosols↗

[Possibilities of using cardioselective beta blocking agents in patients with chronic obstructive bronchopneumopathies].

The use of four cardioselective beta-blockers in a group of patients with chronic obstructive bronchopneumopathies was examined. Of the 4 drugs the only possible one for use in this patient category was atenolol which produced significant bronchial dilation after spray treatment, thus demonstrating the responsiveness of beta 2-receptors to pharmacological stimulus.

Acebutolol↗

[Comparative study of the bronchodilating action of fenoterol and ipratropium bromide administered by aerosols in acute attacks of asthma].

Eighteen patients hospitalised with acute bronchial asthma are examined. Nine were given aerosol treatment with an ipratropium bromide solution and 45 minutes later with a phenoterol solution. The remaining 9 were given the same treatment in reverse order. The results obtained showed that phenoterol has a stronger bronchodilatory activity than ipratropium bromide, especially when administered after the anticholinergic product.

Acute Disease↗

[Double-blind study of the bronchodilating action of the aminophylline-clenbuterol combination in asthmatic patients].

The results obtained with the administration of aminophylline and clenbuterol either separately or in association, to a group of patients with chronic obstructive bronchopneumopathies are reported. The two drugs had a more or less identical broncho-dilatory effect with the beta 2-stimulant acting earlier but for a shorter time. The simultaneous administration of both drugs gave distinctly better results.

Aged↗

[Problems of pulmonary pathology in drug addicts].

The hospitalisation of a group of drug addicts with pulmonary diseases leads to an examination of the relationship between drug addiction and bronchopneumopathies in the light of experience and reported data. After a brief examination of cases, the most frequently observed forms of bronchopulmonary disease are reviewed together with differences in the clinical course of the diseases in drug-addicted and other patients.

Adolescent↗

[Tuberculosis in dialysis patients].

Seven cases of T.B. were observed in 300 patients subjected to dialysis in period 30.4.1977-30.1.1980. This frequency is much higher than that in the ordinary population. An account is given of the statistical and clinical aspects of this morbid associations. The way in which it can be treated is also discussed.

Adolescent↗