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Biomedical subjects

F G Cerrai

Publications and source records attributed to F G Cerrai.

At least 19 recordsLinked to original sources
PubMed1994

Self-expanding tracheobronchial stents using flexible bronchoscopy. Preliminary clinical experience.

Endoscopic insertion of tracheobronchial stents is indicated to achieve patency of the airway in case of malignant or benign obstructing lesions. Until now, the placement of prostheses has required a rigid bronchoscope with specially designed insertion instruments. Self-expanding stents are currently used to treat stenoses of different hollow organs (vessels, urinary tract, gastrointestinal tract, bile duct, respiratory tract). We report the first case of a self-expanding stent implanted in the trachea and right main stem bronchus using flexible videobronchoscope under local anesthesia. The procedure was easy, safe, effective, and well tolerated. No complications occurred.

Aged↗
PubMed1993

Endoscopic treatment of upper gastrointestinal tract malignancies.

Palliative endoscopic treatment of the upper gastro-intestinal (UGI) tract includes: dilation, Nd:YAG laser photocoagulation and intubation, used alone or in combination. These procedures are usually performed on an outpatient basis and are associated with a low rate of morbidity and mortality. From 1978 to 1992, 836 patients were treated at the Endoscopy Division of the Istituto Nazionale Tumori, Milan, for inoperable primary or recurrent malignancies of the UGI-tract. Recanalization was obtained in 96% of patients treated; functional results have been computed according to the site and to the endoscopic method. Overall median survival was 6.2 months. The complication rate was 8%. Relief of dysphagia is the goal of palliative treatment in patients with inoperable neoplasms of the UGI-tract.

Aged↗
PubMed1991

Esophageal intubation for malignant fistulas.

Between April 1978 and December 1989 at the Endoscopy Division of the National Cancer Institute of Milan, 140 patients were intubated for esophageal neoplasms; 19 of these subjects underwent endoscopic intubation for malignant fistulas complicated by pneumonia and/or mediastinitis. The prostheses were tolerated well and enabled the restoration of oral nutrition. The mean survival was 4.7 months (range, 0.5-17 months). No major complications occurred. Tube dislodgement was observed in 2 cases (10.5%). Two patients died of causes that were not related to the procedure.

Aged↗
PubMed1991

Pharyngo-esophageal prostheses in malignancies of the cervical esophagus.

Cervical location of inoperable esophageal carcinoma is usually considered a contraindication of palliative intubation due to technical limitations and complications of the procedure. Between 1978 and 1989, 32 patients with inoperable cancer of the cervical esophagus were treated endoscopically at the Endoscopy Division of the National Cancer Institute, Milan. Eight of them underwent endoscopic intubation. The prostheses were tolerated well and did not cause any respiratory impairment. No complications related to the procedure were observed. In seven of the patients resumption of oral nutrition led to improvement of the general condition. The mean survival time was 5.5 months (range 0.5-23 months).

Aged↗
PubMed1990

[Endoscopic polypectomy of the stomach].

Until 1970 endoscopy of the digestive tract was the only diagnostic method available. After this date, the introduction of endoscopic polypectomy enabled patients affected by these lesions to be treated, and at the same time considerably reduced their length of stay in hospital. The paper reports the results of 346 gastric polypectomies performed in 187 patients from 1974 to the present.

Adult↗
PubMed1990

[A case of cloacogenic carcinoma with extra-visceral localization].

Cloacogenic carcinoma is a rare form of neoplasia (4-14% of tumours of the colon-rectum) which occurs on the transitional epithelium of anal canal. An extra-visceral location is rare. The paper reports a case of cloacogenic carcinoma sited on the perianal skin, treated with radiotherapy and local surgical excision. It is important to perform a biopsy and a thorough endoscopic examination of all ano-perianal lesions in order to separate those of dermatological relevance from those of surgical relevance, and at the same time to determine the exact histological type of the latter group so as to select the correct therapeutical approach.

Aged↗
PubMed1990

Esophageal tumors--treatment by endoscopic intubation.

Esophageal tumors are often inoperable, because of the poor general condition of patients or the coexistence of metastatic disease. Endoscopic intubation is a safe method of palliation in these patients which can restore esophageal patency and lead to an improved nutritional status. At the Endoscopy Division of the National Cancer Institute in Milan, 141 patients with inoperable esophageal cancer underwent endoscopic intubation between 1978 and 1989. The 7-day mortality was 9/141 (6.3%) patients. In 114/132 surviving patients there was an improvement in the nutritional status and general condition. The complication rate was 17.7% (25/141 patients) and the mean survival was 5.9 months.

Adult↗
PubMed1987

[Cancer of the rectum: analysis of incidence and survival at the Casale Monferato Provincial Hospital].

Between 1978 and 1984, 34 patients carrier of rectal neoplasms, were observed and treated in Divisione di Chirurgia Generale of Casale Monferrato Hospital. Twenty of such patients had been operated with curative procedures and 14 with palliative procedures. At the moment of this investigation 14 patients were still alive. The survival rate at 5 years, referred to '78, '79, '80, '81, respectively was 37.2%. For the last three years, the fifth year delay time shall be waited. The survival rates per year, have been reported her, for the whole period of the investigation. The AA, have evaluated the gross incidence rate for male and female patients (3.1 and 2.1 respectively). Survival and incidence data have been composed to those reported in the literature. Whilst survival rates agree with those from other authors, the incidence rates result considerably lower than those from other West Countries. It could be abscribed to an underestimation of the actual number of rectal neoplasm bearing patients, which could escape the investigation because diagnosticed and treated elsewhere. It should be noted nevertheless that the Casale Hospital supplies a scarcely industrialized urban area, and a wide rural environment, so that resident population might be included within one of the groups partially protected by environmental and alimentary conritions against the disease. In conclusion the AA. consider of a primary importance the development of centres suitable for base medicine aimed at assuring a real and effective prevention activity.

Adenocarcinoma↗
PubMed1987

[Carcinoma of the colon. Statistico-epidemiologic study carried out at Casale Monferrato Hospital].

The authors report here on the results of a statistical and epidemiological review of cases of carcinoma of the large bowel observed in the General Surgery Division of the Casale Monferrato Hospital. After supplying introductory data on the diffusion of the disease, risk factors and statistical aspects, the authors report data on 137 cases of large bowel carcinomatous neoplasms observed and treated over the period 1978-1984, complete with tables summarising the neoplastic localizations aid the types of operation performed. After calculating the operative mortality and both the absolute and relative survival rates, the authors analyze the results of the survey, comparing the findings obtained with those reported in the literature by various authors.

Adenocarcinoma↗
PubMed1986

[Occlusive neoplastic pathology of the large intestine (a clinical contribution)].

The Authors report an investigation on 42 patients with large bowel occlusions for neoplastic lesions. Obstruction complications were localized in 69% in sigmoid colon and recto-sigmoid junction. This pathology involved old patients with one or more associated affections. The Authors explain reflections on surgical treatment, on necessity of therapeutic approach in high-risk patients, and of large bowel surgery with oncologic radical treatment.

Adult↗
PubMed1985

[Carcinoma of the prostate: statistico-epidemiologic study at Casale Monferrato Hospital (1980-84)].

An investigation on prostatic dancer is reported by AA., along a five years period (80-84) in Casale Monferrato territory (USSL 76, Piedmont) incidence rate (29,8) aid mortality data (27,7) are also reported in comparison to those reported in "Registro Tumori del Piemonte (Turin)", "Registro Tumori Lombardia (Varese)" and ISTAT (national territory). A. marking differencies among reported data, give some explanation about disagreement. AA.'s further assert that the given under-estimation of the incidence rate is due to the different diagnosis in different USSL. The over-estimation of death rate is partially given first by people come back in primitive country of origin, and second by data acquired in original countries, about death.

Aged↗
PubMedDate not supplied

Endoscopic stent placement for cancer of the lower esophagus and gastric cardia.

We reviewed our results of using stents for palliation of cancer of the lower third of the esophagus and gastric cardia. During a 14-year period, 76 patients with either lower third esophageal cancer (n = 43) or cancer of the gastric cardia (n = 33) received stents for palliation of malignant dysphagia. Successful endoscopic placement was initially achieved in all patients, with 71 patients available for follow-up. Of these, 40 (56%) were subsequently able to eat solid or semi-solid food, 25 (35%) could swallow only liquids, and 6 (8%) were unimproved. The combined early and late complication rate totalled 22%. Early complications included perforation (n = 3) and stent migration (n = 4); late complications consisted of dislodgment (n = 6), obstruction by tumor (n = 2), and severe esophagitis (n = 1). There were no procedure-related deaths, but survival at 1 year was estimated to be only 1.5%, with a median survival of 2.5 months after stent insertion. The endoscopic placement of prosthetic stents for cancer of the distal esophagus and gastric cardia entails a higher complication rate, less successful palliation, and shorter survival time compared to similar treatment for more proximal esophageal cancer.

Aged↗