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Biomedical subjects

F Flores

Publications and source records attributed to F Flores.

At least 73 records · Page 4Linked to original sources
PubMed1987

Chemical composition and nutritional value of Mexican varieties of chickpea (Cicer arietinum L.).

Chemical composition and protein quality of the main chickpea varieties cultivated in Mexico were determined. The raw and cooked chickpeas analyzed were: Surutato, Surutato 77, Sonora, Sonora 80, Porquero, Macarena, Breve Duro and a mixture of broken seeds used mainly for animal feeding. The chemical composition of the raw chickpea studied was very similar; the average values of the nutrients were: ash 3.1 +/- 0.2, fat 5.0 +/- 1.0, protein 19.5 +/- 1.2 and fiber 3.7 +/- 2.1. Cooking diminished only the ash content and the Porquero variety was the only one that had a high content of crude fiber (9.1%). There was not found agglutinating activity to rabbit RBC in any of the raw chickpeas studied and the trypsin inhibitor activity average was 11.8 +/- 2.4 TUI/mg sample. Cooking destroyed 57% of this activity. Digestibility was the same in the raw and in the cooked chickpea (78%). There were not found significant differences in the PER values of the raw and cooked seeds: 1.65-2.30 and 1.80 to 2.61 respectively. The Surutato and Breve Duro varieties were statistically similar to the casein PER (2.5). It could be recommended to use these two varieties mainly for infant feeding.

Caseins↗
PubMed1986

The contractile action of palytoxin in the isolated rabbit urinary bladder.

Palytoxin at 10(-10)-10(-7) M caused contractions of the detrusor muscle from rabbit urinary bladder in a concentration-dependent manner. The response to palytoxin was markedly inhibited by indomethacin (a cyclooxygenase inhibitor) or nordihydroguaiaretic acid (a lipoxygenase inhibitor) at 10(-5) M. Indomethacin and nordihydroguaiaretic acid also inhibited the response to arachidonic acid at 10(-3) M. A Ca2+-free medium with EGTA or nifedipine at 10(-5) M, nearly abolished the responses to palytoxin and arachidonic acid. Tetrodotoxin, phentolamine, atropine and chlorpheniramine (all at 10(-5) M) had a slight or no inhibitory effect on the response to palytoxin. These results suggested that in the rabbit bladder, the contractile effect of palytoxin is mainly dependent on an increase in metabolites of arachidonic acid.

Acrylamides↗
PubMed1986

Potent alpha-adrenoceptor blocking action of SGB-1534, a new quinazoline antihypertensive agent in vitro experiments.

SGB-1534 inhibited the contractile response to norepinephrine (NE), methoxamine (MO) and electrical transmural stimulation in the rabbit aorta, basilar and cat coronary arteries and only in the rabbit aorta its inhibitor action was a competitive manner. In the rabbit aorta, the potency (pA2) of SGB was greater than that of prazosin, whereas in the other preparations, the effect of SGB was comparable to that of prazosin. In the rabbit aorta, both SGB and prazosin abolished the contraction induced by transmural stimulation. In the guinea-pig vas deferens, SGB failed to affect the inhibitory effect of clonidine on the response to electrical field stimulation. SGB had no inhibitory effects on the contractile response to potassium, 5-hydroxytryptamine, PGF2 alpha and an excess Ca2+ and the relaxing response to isoproterenol in the vascular tissues. In the electrically driven left atria of guinea-pigs, SGB had no effect on the electromechanical parameters and the isoproterenol induced inotropic effect. On the specific binding of [3H]prazosin in the rabbit aorta, the inhibitory effect of SGB was greater than that of prazosin and phentolamine.

Adrenergic alpha-Antagonists↗