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Biomedical subjects

F Feliciotti

Publications and source records attributed to F Feliciotti.

54 records · Page 3Linked to original sources

[Treatment with total parenteral nutrition in inflammatory diseases of the intestine].

The authors present 33 cases of inflammatory diseases of the bowel (15 cases of Crohn's disease and 18 of Ulcerative Colitis) and patients are divided into 3 groups according to clinical, laboratory and pathological parameters. Also from the results obtained, they believe that T.P.N. is particolary indicated in patients of the second stage, in which T.P.N. has double function. It permits an adequate alimentation and reintegration of protein, vitamins as well as hydro-electrolytes. Allowing the intestine to rest it also repair its mucosa.

Adolescent↗

[Experience with cefoxitin in surgical sections of intensive care wards].

The Authors illustrate the results obtained in treatment of various types of infection in patients hospitalised in an intensive care surgical department with cephoxitin, a new semisynthetic antibiotic derivate of the cephalosporin group. In view of the severity of the treated cases, the Authors consider the results obtained to be satisfactory.

Adult↗

[Retroperitoneal tumors].

The authors after giving a general view of retroperitoneal tumors also describe briefly their anatomo-clinical features pointing out the controveries of these neoplasms. Personal case histories are illustrated emphasizing the importance of shortening the time of diagnosis in regards with already sintomatic neoplasms which are misdiagnosed. The efficiency of present methods of diagnosis in relation with therapeutic problems is documentated and acknowledged.

Adolescent↗

[Peripheral schwannomas: a case report].

The Authors present 10 cases of peripheral schwannomas observed in the Ancona University Surgical Clinic in the five-year period 1976-1980. An examination is made of the frequency of the various symptoms in relation to the different localisations, the diagnostic techniques, among which particular importance is attributed to echo tomography, and the principles underlying surgical treatment.

Adult↗

[Heterotopic homograft of the rat stomach: microsurgical technic].

More than by a practical viewpoint, the experimental graft of stomach is very useful like model for the study of gastrointestinal physiopathology. Starting from these considerations the AA. have set up a new method for the execution of stomach heterotopic homograft in rat and they have studied the secretory activity without immuno-suppressed therapy. Not inbred rats have been used; their middle survival has been of 9,3 days. The secretion has been regular up to 5th-6th day; in the same time the AA. have made histopathologic studies on the transplanted stomachs of animals that had been sacrificed at programmed intervals of time, which have outlined the progressive growth of a reaction of intense immunological rejection.

Animals↗

[Orthotopic homograft of the rat stomach: microsurgical technic].

The principal aim of this study is to set up a new microsurgical technique that can be reproducible easily for the execution of orthotopic homograft of stomach in rat. The vascularization of homograft is given, for arterial district by a termino-terminal anastomosis between celiac artery of donor and right renal artery of receiving, and, for venous district, by a termino-lateral anastomosis between portal vein of donor and vena cava of receiving. The middle survival of rats that were had a graft, in this first stage of research, has been of 3 days, therefore it hasn't't been possible to look into the function of graft.

Animals↗

[Mechanical sutures in digestive surgery. II. An experimental study of the cicatricial repair process].

The AA. intend to study the healing process of digestive sutures in dog that have been made with mechanical instruments that have metal agraphes. The used instruments are the American models of United Surgical Corporation in New York that have: --LDS pliers; --GIA pliers; --TA mod 90, 55, 30, pliers. They had made 15 operations of digestive surgery: gastric resections sec. Billroth II, anastomoses of ileum, colic anastomoses. In total they have made 45 sutures. After an established period the same animals were operated on again for controlling the results of made operations and the macro and microscopic evolution of sutures. The study of healing has shown a quick and exact repairing process for first intent, different from sutures that are made manually with threads that, notoriously, develop slowly for second intent.

Animals↗

[Echography in minimally invasive surgery].

Thanks to the great development of laparoscopic surgery and his continuous technical evolution, echography plays more and more important role in the pre- and intraoperative diagnosis. In the hepato-pancreatic pathology the use of the laparoscopic echography reduces clearly the role of laparotomic exploration. In laparoscopic surgery of rectal-colon, the echography is more specific and sensitive in compared with pre-operative MR and CT to individualize liver metastasis, to locate them. This allows the treatment of such lesions through the cryosurgery. In pancreatic lesions such method plays a non releasable role in tumors staging, giving essential elements to the surgeon to operate and for a better definition of operative strategy. Also in the adrenal masses surgery, laparoscopic echography reveals very useful especially in the anatomical structures identification (i.e. renal vein and entrance of the left adrenal vein) in the patients already operated or obese. In the preoperative study of rectal tumors the use of rotating and transrectal probes allows to define the degree of infiltration of the lesion and to perform a mini-invasive treatment through endoscopic transanal microsurgery with the radiochemotherapy. Thus echography in mini-invasive surgery has an unreplaceable role both in diagnosis as in evaluation of the parameter of therapeutical approach.

Adrenal Gland Neoplasms↗

Laparoscopic colonic resections versus open surgery: a prospective non-randomized study on 310 unselected cases.

BACKGROUND/AIMS: Laparoscopic colorectal surgery, particularly for malignancy, is still debated. The aim of this study was to prospectively evaluate the postoperative outcome as well as the short- and medium-term results of laparoscopic surgery compared with those after open conventional surgery. METHODOLOGY: A series of 310 consecutive patients, operated on by the same surgical team, have been included in this study; 150 patients (75% with malignant lesions) underwent laparoscopic surgery, whereas 160 patients (73% with malignant lesions) were treated by open surgery. The treatment modality was selected by the patients after reading the informed consent form. RESULTS: Laparoscopic surgery was technically feasible in 91.4% of cases. Mean operative time for laparoscopic surgery was longer than for open surgery (251 vs. 175 min) (P < 0.001). Mean postoperative hospital stay after laparoscopic surgery was 10.5 days, as compared to 13.3 days after open surgery (P < 0.05). In the laparoscopic surgery group minor complications' rate was 3.6% and compared favorably to the 7.5% observed after open surgery (P = 0.261). No statistically significant difference was observed in the major complications rate (9.4% after laparoscopic surgery and 6.8% after open surgery) and in operative mortality (1.4% for laparoscopic surgery and 0.6% for open surgery). The local recurrence rate was lower after laparoscopic surgery as compared to open surgery: 3% versus 9.2% (P = 0.152), respectively. Mean follow-up was 34.2 months during which time we observed 2 cases of port site recurrence. After implementing adequate prophylactic measures, no parietal implants were observed in the last 80 patients who underwent laparoscopic surgery for malignancy. Distant site metastases occurred in 11% in both groups. At 36 months cumulative survival probability in laparoscopic surgery completed malignant cases was 0.74% as compared to 0.66% after open surgery. CONCLUSIONS: Morbidity and mortality were similar in the 2 groups. Laparoscopic patients experienced less pain. A slightly higher incidence of local recurrence was observed in the open surgery group, whereas the percentage of distant site metastases and the cumulative survival probability in the 2 groups were similar. Port site recurrences are a cause of concern but they can be prevented with adequate prophylactic measures. The short- and medium-term results of laparoscopic surgery compared favorably with those of open surgery in this prospective non-randomized study. Long-term oncological result are not known yet. In patients with malignancy prospective randomized trials on larger patient numbers are required.

Colectomy↗

[Single-stage laparoscopic surgery of cholelithiasis and choledocholithiasis in 268 unselected consecutive patients].

AIMS: The introduction of laparoscopic cholecystectomy (LC) has modified the treatment of gallstones and common bile duct (CBD) stones. Aim of this prospective study was to evaluate the results of single stage laparoscopic management of gallstones and CBD stones. PATIENT AND METHODS: From January 1991 to October 1999, CBD stones were present at intraoperative cholangiography in 268 patients (pts) (169 females, 99 males, mean age 55.6 years, range 12-94 years) out of 2693 undergoing LC (10%) for gallstones. CBD stones were unsuspected in 123 (45.9%) and suspected in 145 (54.1%). RESULTS: CBD exploration was successful in 264 cases (98.5%) (transcystic 164, choledochotomy 100). Four pts were converted to open surgery (1.5%). Retained stones in 15 patients (5.7%), were treated by ERCP/ES (6 pts) and by percutaneous endoscopic/fluoroscopic stone removal (6 pts). Spontaneous stones passage occurred in 2 pts, one patient is waiting for treatment. Major morbidities were hemoperitoneum (4 cases) and cystic duct bile leakage (3 cases). One high risk patient died postoperatively. Recurrent stones were observed in 5 pts (1.9%), at 1, 4, 8, 18, 26 months respectively after T-tube removal, and were treated by ERCP/ES in 4 cases. Spontaneous stone passage occurred in 1 case. CONCLUSIONS: LC and CBD exploration has shown to be safe and feasible with low morbidity and mortality. The rationale of this approach is to solve two problems during the same procedure, limiting the role of endoscopic sphincterotomy to the treatment of residual ductal stones.

Adolescent↗