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Biomedical subjects

F Fantini

Publications and source records attributed to F Fantini.

At least 163 records · Page 9Linked to original sources
PubMed1980

[Carcinoid heart disease. Report of a case (author's transl)].

A case of carcinoid tumor characterized by isolated tricuspid insufficiency with stenosis is reported. This valvular disease was characterized by a slight increase of cardiac output and pulmonary pressures. Necropsy did not evidence the site of the primitive tumor. Tricuspid valve lumen was near normal while the pulmonary valve presented slight stenosis. The correlations between clinical feature and necroscopic findings are discussed.

Autopsy↗
PubMed1979

Effect of isoproterenol on the "early repolarization" syndrome.

A study has been carried out on a group of subjects with RS-T segment elevation, a normal variant of early repolarization. Following isoproterenol administration, the RS-T segment became isoelectric. In most cases this was accompanied by shorter QT and longer QTc intervals. The same effects were observed after physical exertion but not after atropine or amyl-nitrite. Propranolol administration exaggerated RS-T elevation. Considering the mechanism with which isoproterenol acts and some analogies with the electrocardiographic picture experimentally obtained by means of the unilateral stimulation of the stellate ganglions, the hypothesis is advanced that the normal variant of early repolarization is related to an enhanced activity of the right sympathetic nerves.

Adult↗
PubMed1979

Hemodynamic effects of nitroglycerin.

The authors have studied the hemodynamic effects of sublingually administered nitroglycerin (NG). Obtained data indicate that the response to NG is time-dependent. A first phase, lasting about 2 minutes, is characterized by a reduction of total systemic resistance (TSR) and an increase of cardiac output (CO), without significant variations of left ventricular filling pressure (FP) and blood pressure (BP). A modest increase of heart rate (HR) is observed. The second phase is characterized by a reduced FP and later, after 5 minutes, of BP. Subsequently HR increases to a greater degree, CO decreases and TRS presents a variation toward control values.

Female↗
PubMed1979

Assessment of sinus node function in asymptomatic subjects with sinus bradycardia and in symptomatic patients with sino-atrial disease.

Sinus node function was evaluated in 18 patients with sinus bradycardia without complaints (Group I), in 16 patients with sinus bradycardia and/or sinoatrial block with complaints (subgroup IIa) and in 14 patients with the bradycardia-tachycardia syndrome (subgroup IIb). Mean values of corrected sinus node recovery time (CSRT), atrial effective refractory period (AERP) and atrial functional refractory period (AFRP) differentiated significatively asymptomatic subjects of group I from the two subgroups of patients with sinoatrial disease, but failed to differentiate each subgroup from the other one. There was no significative difference in mean sinoatrial conduction time (SACT) between group I and each of the two subgroups. Three patients of subgroup IIa and 1 patient of subgroup IIb had a false negative response after both overdrive and premature programmed atrial pacing. Spontaneous cycle length was directly correlated with the sinus node recovery time and the atrial refractoriness in group I, and with the only sinus node recovery time in subgroup IIb. No direct correlations were observed in subgroup IIa. This suggests a less disturbed sinus node automaticity in bradycardia-tachycardia syndrome.

Arrhythmia, Sinus↗
PubMed1978

[Dynamic geometry of the left ventricle. Relaxation and elasticity indices].

A study was made of 34 patients with valve defects or arterial hypertension and a haemodynamic picture of left ventricle pressure or volume load. Echocardiography and haemodynamic investigated-established the size and mass of the left ventricle and also enabled its indices of contractility, relaxation and distensibility to be determined. The series was divided in accordance with the dynamic geometry of the left ventricle. In concentric hypertrophy, telediastolic rigidity increased in proportion to ventricular thickness and mass. In eccentric forms and ventricular dilatation, diastolic distensibility was reduced in cases with a high filling pressure. The relaxation values bore no relationship to distensibility and telediastolic compliance. The relaxation rate in protodiastole diminishes in proportion to functional depression of the left ventricle.

Cardiac Catheterization↗
PubMed1978

[A preliminary study on parietal stress decay in patients with left ventricular hypertrophy (author's transl)].

In order to determine equatorial and radial stresses at various depths of left ventricular wall, left ventricular pressures and echocardiographic dimensions were elaborated using the formula proposed by Timoshenko. Patients with concentric left ventricular hypertrophy (LVH) have minor end-diastolic and end-systolic decay of radial and equatorial stresses, compared to patients with eccentric LVH. The total stress affecting left ventricular wall is significantly minor in telediastole than in telesystole.

Adult↗
PubMed1978

[The Doppler-echocardiography in the study of transvalvular pulmonary flow (author's transl)].

The AA. studied 96 subjects: 74 normals, 15 patients with pulmonary stenosis, 6 with pulmonary regurgitation and 1 with combined stenosis and pulmonary regurgitation, by using pulsed Doppler echocardiography. This technique, which supplements M-mode echocardiography with Doppler flow detection, allowed determination of direction and quality--laminar or turbolent--of flow through pulmonary valve. In our experience, pulsed Doppler echocardiography is a sensitive and specific method for detection of pulmonary stenosis and regurgitation and extends ultrasound diagnosis beyond the capabilities of M-mode echocardiography.

Blood Flow Velocity↗
PubMed1978

[Doppler echocardiography in the diagnosis of tricuspid anomalies (author's transl)].

Doppler echocardiography has been applied in a study of the tricuspid and central venous blood velocity curves in a number of cases, including eleven cases of insufficiency, six cases of stenosis, five cases of steno-insufficiency of the tricuspid valve and one case of Ebstein's disease. The tracings were compared to normal reports and to those appartaining to a few patients with right ventricular failure from different causes. For six patients the venous blood velocity curve was recorded contemporaneously with the right atrioventricular pressure curves. Doppler echocardiography has proved that it can offer useful indications on tricuspid anomalies. The analysis of the central venous and tricuspid blood velocity curve allows us to detect hemodynamic alterations characteristic of this valvular disease.

Blood Flow Velocity↗