Professor Hans Goldmann died in Bern on November 19th, 1991 at the age of 92 years. His outstanding intellectual capacity was discovered at an early age and demonstrated throughout his life. He was appointed as teaching assistant of the famous A. Cermak von Seysenegg, Chairman of the Institute of Physiology of the German Charles University in Prague. During his stay at the University of Prague, he was influenced by the famous people of his time, such as Einstein (physicist), Mach (physicist and psychophysicist), Lorenz (behavioral scientist), Popper (philosopher), Schlick (physicist and philosopher), Hering (physiologist), and others. Goldmann absorbed the essence of these disciplines to a very large extent. This, together with his remarkable intellect, enabled him to produce outstanding research work within a large spectrum of sciences more or less directly related to ophthalmology. Goldmann became known in particular for his exceptional and fundamental work on perimetry and glaucoma and he managed to cast his basic insight into practical, easy-to-operate, high-precision diagnostic instruments which, several decades after their invention, are still used by every ophthalmologist. He will enter history as one of the very great pioneers in ophthalmology.

Czechoslovakia↗

PubMedDate not supplied

The use of the G1 and Octosmart programs in detecting temporal changes in the visual field.

PURPOSE: The Octopus program Octosmart is able to classify visual fields into six classes. In the program a horizontal bar indicates these classes, and an indicator points to the most probable position, related to the measured pathology. The width of this dashed indicator shows the range of possible fluctuations in the measurement and, therefore, its precision. This study sets out to analyse the suitability of this display mode using other visual-field index data. METHODS: The visual fields of 83 glaucomatous eyes of 61 patients of various etiological groups and glaucoma suspects were studied for periods varying from 1 to 5 years in a retrospective study. All examinations were performed with the G1 Octopus program and analyzed with the Octosmart program. The statistical significance of linear trends of the visual-field indices, mean defect (MD) and corrected loss variance (CLV), and the class shown by the indicator (POI = position of indicator) were determined, and their regression coefficients were analyzed by means of a linear trend test as a function of time. RESULTS: Of the sample of 83 tested eyes, a total of 18 significant trends were recorded after five examinations. All visual-field indices showed a trend towards amelioration. CONCLUSIONS: The 18 significant trends observed must be attributed to perturbing long-term fluctuations and, despite their statistical significance, are of little clinical value. It is questionable whether an increased number of examinations per eye would have attenuated the threshold fluctuations sufficiently to make the change in field class more reliable.

Adult↗

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[An information psychology examination of form perception].

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Form Perception↗

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Oculoplastic surgery with a contact Nd:YAG laser silica scalpel. A case report.

Baso-cellular carcinomas involving the medial canthal regions of both eyes were resected using a 10 W cw-Nd: YAG laser scalpel. The wound bed was repaired one side by a free, split-thickness graft and on the other by a frontal pedicle flap. Surgery was, for the most part, virtually bloodless. Since laser radiation immediately seals both capillaries and lymphatics, the incidence of postoperative hemorrhage and edema was significantly less than after cold scalpel surgery. Healing was uneventful. The advantages of laser-assisted surgery are worthy of consideration: not only is the operation time markedly curtailed, but the wound healing response is excellent, with only a minimal inflammatory reaction.

Aged↗

PubMedDate not supplied

Spontaneous and pharmacologically-modulated wound healing after Nd:YAG laser sclerostomy ab interno in rabbits.

UNLABELLED: The course of tissue repair evoked by Nd:YAG laser sclerostomy ab interno and the effect of mitomycin-C on same were investigated ultrastructurally in 15 rabbits. In ten of them, the dynamics of the spontaneous postoperative healing response (i.e. in the absence of medication) was analyzed at two-day intervals by light- and electron microscopy. In two, fibroblast activity was assessed autoradiographically. In the last three rabbits, the sclerostomy site was exposed transconjunctivally to mitomycin-C (0.5 mg/ml; 5 minutes) before surgery, and morphological analysis was done on postoperative days 6 and 12. RESULTS: In the spontaneously healing group, blebs disappeared within five days of surgery. This corresponded to a massive invasion of macrophages and fibroblasts from the episclera and iris root. The sheath of coagulated tissue around the fistula appeared to act as a barrier to cell migration from the sclera itself at this stage. By days 8 to 12, the canal had become occluded by a network of cells and capillaries, and collagen fibrils in the coagulation sheath had undergone repolymerization. In the mitomycin-C group, large filtering blebs and patent, cell-free fistulas were observed over the entire period. Although applied transconjunctivally, the drug penetrated the whole scleral depth, as the iris root and ciliary body cell reaction was inhibited. Repolymerization of heat-damaged collagen was also hindered. The overall findings provide information on the sequence of repair events following laser sclerostomy. Local, non-invasive application of mitomycin-C delays the onset of this process, not only by inhibition of cell proliferation but also by suppressing the collagen recovery.

Animals↗

PubMedDate not supplied

Nd:YAG laser sweeping of an intraocular lens.

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Cell Adhesion↗