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Biomedical subjects

F F Holmes

Publications and source records attributed to F F Holmes.

At least 73 records · Page 4Linked to original sources

Carcinoma distantly metastatic at diagnosis: improvement in survival, 1945-1974.

Survival rates for 3,842 Kansas and Missouri patients with carcinoma metastatic at diagnosis who were registered between the years 1945 and 1974 were examined. While there was no improvement in survival comparing the 1945-1954 and 1955-1964 decades, there was significant recent improvement in survival when the 1,805 patients diagnosed from 1945 to 1964 were compared to 2,037 patients diagnosed from 1965 to 1974. It was concluded that even in this particularly unfavorable presentation of cancer, there has been definite improvement in survival in the past decade.

Female↗

Three primary cancers in different organs.

In a registry of 24,105 cancers, 15 patients were found to have three primary cancers in different organs. Decreasing time intervals between sequential diagnoses and then death were noted. Occurrence and sequence of cancer sites appeared to be random. Stage of second and third cancers tended, on the average, to be more advanced than those of the first cancers. This study strengthened the hypothesis that patients with primary cancers in different organs are victims of compromised host defenses against cancer.

Aged↗