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Biomedical subjects

F Ellison

Publications and source records attributed to F Ellison.

3 recordsLinked to original sources

Culturally informed social work practice with American Indian clients: guidelines for non-Indian social workers.

Culturally informed social work health and mental health interventions directed toward American Indian clients must be harmonious with their environment and acculturation. This article discusses American Indian beliefs about health and illness and degrees of acculturation. Guidelines are offered to help non-Indian social workers design culturally appropriate interventions.

Acculturation↗

An examination of heroin conditioning in preferred and nonpreferred environments and in differentially housed mature and immature rats.

The study addressed two issues. First, we examined the effectiveness of heroin as a conditioning agent in a preferred environment using a place preference paradigm. Four daily injections of 80 micrograms/kg (SC) of heroin HCl were paired with environments that rats initially found to be either preferred or non-preferred. In subsequent tests, only those that had experienced the drug effects in the non-preferred environment increased the percentage of time spent in that environment. Rats conditioned in the test chamber that was initially preferred failed to increase the amount of time spent in that chamber post-conditioning. These results suggest that the conditioned place preference paradigm does not simply assess the rewarding consequence of heroin injections. We also examined the effects of grouped and isolation housing conditions on the heroin-produced conditioned place preference. Rats were housed under these conditions either immediately post weaning or at 120 days of age. There was a difference between the magnitude of the place preference produced by 20 micrograms/kg heroin in the isolated but not in the group housed rats. When isolated at weaning the rats were less sensitive to the drug than were rats isolated at maturity. These data are discussed with particular reference to the development of the endogenous opioid system.

Aging↗

Opiate withdrawal and electro-stimulation. Double blind experiments.

A rapid detoxification technique for heroin addicts is described. The technique uses an impulsional electric current developed by Limoge. The treatment is nonaggressive, very well tolerated by the addicts and leads to a good psychotherapeutic relationship with the medical staff. A successful physical detoxification is achieved in more than 80% of the cases (this figure is based on 400 patients treated by the method). The technique was subjected to two double-blind experiments. The first experiment tested the real efficacity of the electrical stimulation. The difference between the group of subjects stimulated and the unstimulated control group had a "p-value" which was significant at the 0,5% level. This leads us to believe that the electrical stimulation has a real positive effect. The second experiment reconfirmed the efficacity of the stimulation and showed that 24 hour continuous stimulation was not sufficient to produce a lasting effect. After about 50 hours stimulation a Naloxone test produced little or no reaction in the patients.

Adult↗