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Biomedical subjects

F E Musiek

Publications and source records attributed to F E Musiek.

At least 73 records · Page 4Linked to original sources
PubMed1986

Neuroanatomy, neurophysiology, and central auditory assessment. Part II: The cerebrum.

In this second article of a three-part series, the auditory areas of the cerebrum are defined. Anatomical descriptions of various structures within the auditory areas of the brain as well as an overview of selected electrophysiological research on auditory cortex are presented. Ablation studies involving auditory cortex and principal aspects of the vascular neuroanatomy are also reviewed. Finally, extensive clinical findings are presented from a case with damage to the cerebral auditory areas.

Animals↗
PubMed1986

Neuroanatomy, neurophysiology, and central auditory assessment. Part III: Corpus callosum and efferent pathways.

In this, the last of a three-part series on neuroanatomy/physiology related to central auditory assessment, two topics will be presented: the corpus callosum and the efferent auditory system. A general anatomical description of the corpus callosum is followed by information on the topographical representation of the cortex within the corpus callosum. Auditory areas of the corpus callosum and the transcallosal auditory pathway are emphasized. Data on transfer time across the corpus callosum and the possible role of inhibitory and excitatory fibers of this commissure are presented. Neuropsychological studies relative to neuroanatomy/physiology of the corpus callosum are discussed, and the efferent auditory system from cortex to cochlea is described. Emphasis is placed on the structure and function of the olivocochlear bundle along with some clinical relationships to probable disorders of the descending pathway of the caudal brain stem.

Agenesis of Corpus Callosum↗
PubMed1986

Central auditory function following anterior sectioning of the corpus callosum.

This paper describes auditory findings for eight patients with anterior sections of the corpus callosum. Peripheral (pure tone and speech recognition) and five central auditory tests were administered to each of the eight patients prior to surgery and then again approximately 2 weeks after surgery. The central tests administered included a low-pass filtered speech test, the frequency patterns perception test, and three dichotic speech tests. Mean scores for the peripheral tests fell grossly within the normal range preoperatively and showed little change postoperatively. Similarly, scores on the central tests, though somewhat more variable, did not show any obvious differences upon pre- and postsurgical comparison. A comparison of these results with those reported previously for patients with complete commissurotomies (Musiek, Kibbe, and Baran. Semin Hear 1984;5:219-29) revealed that as a group, patients with anterior sections of the corpus callosum showed fewer postsurgery deficits than did the subjects with complete commissurotomies. The lack of an apparent auditory effect in the anterior group is believed to have an anatomical basis.

Adult↗
PubMed1986

ABR results in patients with posterior fossa tumors and normal pure-tone hearing.

Sixteen patients with confirmed mass lesions of the posterior fossa and normal hearing sensitivity for pure tones were studied. Patients' main symptoms, auditory brain-stem response (ABR), and lesion size were analyzed. All patients manifested neurologic and/or otoneurologic symptoms or complained of hearing difficulty disproportionate to their pure-tone findings. Interestingly, the patients in this select group were younger (mean = 34 years) than the typical patient with a posterior fossa tumor. ABR results were abnormal in 15 of the patients, although several indices--including absolute and interwave latencies, interaural latency difference, and wave presence/absence--were employed to achieve this sensitivity. Lesion size varied considerably and failed to correlate with ABR or pure-tone results.

Adult↗
PubMed1986

Auditory brain stem response wave IV-V abnormalities from the ear opposite large cerebellopontine lesions.

This report focuses on auditory brain stem response (ABR) from the ear contralateral to large cerebellopontine angle (CPA) tumors. Specifically, eleven of fifteen patients with large CPA tumors demonstrated contralateral ABRs for which wave IV and/or V were abnormal, while waves I and III were normal. In some cases, waves IV and/or V were absent, while in other cases one or both waves were delayed. The clinical interpretation for this type of ABR finding and the possible implications in relation to generator sites of the various ABR waves are discussed.

Adult↗
PubMed1985

Release from central auditory competition in the split-brain patient.

We used dichotic digits (DD), staggered spondaic words (SSW), and frequency patterns (PATT) to study central auditory function before and after two-stage callosotomy. Preoperatively, the patient demonstrated reduced scores bilaterally on all these tests, consistent with documented bilateral hemisphere lesions. After the first operation (sectioning the posterior half of the corpus callosum), the dichotic tests (DD and SSW) revealed the expected decrease in left-ear scores, but there was improvement on the right, perhaps because there was release from central auditory competition. Our findings also suggest that the "auditory" portion of the corpus callosum may be in the posterior half of this structure.

Adult↗
PubMed1984

Past, present, and future applications of the auditory middle latency response.

For many years (auditory) middle latency response (MLR) reportedly has been an excellent electrophysiological procedure for estimating frequency specific auditory thresholds. Currently the 40 Hz potential, a derivative of the MLR, holds even greater promise for threshold testing. MLR also appears to have potentially valuable applications in the evaluation of functional hearing loss and assessment of higher auditory function. However, MLR is not without controversy. Questions of origin, filtering effects, and its use in pediatric assessment are current issues surrounding applications of MLR. The following article analyzes the values and limitations of MLR within the framework of past, present, and future research and clinical uses.

Acoustic Stimulation↗
PubMed1984

Bilateral congenital oval window microfistulae in a mother and son.

This article details case histories of a son and his mother who were studied over a seven-year period before making the diagnosis of bilateral oval window microfistulae in both of them. The boy demonstrated a slowly progressive bilateral and symmetrical sensorineural hearing loss closely resembling that of his mother. The case reports emphasize their respective histories, diagnostic evaluation, surgical observations, and treatment.

Adult↗
PubMed1982

Audiologic findings in Charcot-Marie-Tooth disease.

An audiologic study of a 54-year-old patient with Charcot-Marie-Tooth disease whose initial symptom was hearing difficulty is presented. While findings from basic audiologic tests were not consistent with the degree of auditory difficulty reported by the patient, special testing did indicate a notable deficit. Although the auditory periphery was probably mildly involved, it seemed that the major auditory deficit was central.

Audiometry, Evoked Response↗
PubMed1982

ABR in eighth-nerve and brain-stem disorders.

Auditory brain-stem response (ABR) results are reported on three cases of acoustic tumors and two cases with brain-stem lesions. These cases highlight several considerations in the clinical use of ABR. The sensitivity of ABR to retrocochlear involvement in light of normal pure-tone hearing and cochlear hearing loss is shown in the first two cases. The third case shows the advantage of "contralateral" ABR testing and a unique effect of stimulus polarity. The use of an intensity function and high presentation rate procedures are shown to be helpful diagnostic procedures in case four. Case five shows bilateral ABR effects which correlate well with the degree of brain-stem involvement. In addition to the ABR data, audiologic, radiologic, and medical findings on these patients are also discussed.

Adult↗
PubMed1981

Staged commissurotomy and central auditory function.

Two young right-handed men with normal peripheral hearing underwent a "staged" commissurotomy procedure. At the first surgical setting, approximately the posterior half of the corpus callosum was sectioned. Approximately two months after the first operation, the remaining portion was surgically disconnected. Extensive central auditory assessment indicated little deficit after each surgery, which was not the case in previous data on patients with commissurotomy at one setting. We discuss possible mechanisms for these differing results, along with the advantages of the staged surgical procedure.

Adult↗
PubMed1980

Reversible neuroaudiologic findings in a case of right frontal lobe abscess with recovery.

A patient with a large right frontal lobe abscess was administered a battery of audiologic and neuroaudiologic tests. Results indicated a definite central auditory processing deficit with essentially normal peripheral hearing. The same test battery was given three months later, after the abscess had completely resolved. The neuroaudiological results on retest were essentially normal for the entire test battery. The specific central auditory processing deficit noted in this case is discussed, along with details of the neuroaudiologic assessment.

Auditory Diseases, Central↗
PubMed1980

Auditory pattern perception in 'split brain' patients.

Three "split brain" subjects with normal peripheral hearing were tested on identifying monaurally presented auditory intensity and frequency patterns. One subject was tested before commissurotomy, ten days later, and one year after surgery. Results indicated that sectioning the corpus callosum dramatically affects the ability to verbally report both intensity and frequency patterns. However, the ability of the subjects to correctly "hum" frequency patterns was not impaired. Thus, it appears for a correct verbal report of an auditory pattern, interhemispheric transfer of acoustic information is required, while "humming" the pattern does not. Further application of this finding implicates auditory pattern tasks as as a potentially valuable test for detecting problems of higher auditory processing, particularly those affecting interhemispheric interaction.

Auditory Pathways↗