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Biomedical subjects

F Dressler

Publications and source records attributed to F Dressler.

48 records · Page 3Linked to original sources

Steroid treatment of pseudo-croup.

In a randomized, controlled investigation, 349 children with pseudo-croup stage I or II were given 6 mg of dexamethasone or placebo. Although the rate of recovery was similar in both groups, there was a significant difference when only the more seriously affected children were considered: steroid treated patients recovered quicker. Steroids appear to be useful in the routine treatment of simple, uncomplicated pseudo-croup, even if their effect apparently is not very impressive. Thus, close supervision remains the most important measure in this nearly always benign but potentially dangerous condition.

Acute Disease↗

[The antipyretic effect of Lonarid N in children].

Lonarid N was used in 78 children suffering from different febrile diseases. It was available in suppositories for infants and children. Body temperature dropped to subfebrile values in 78.5% of all doses. In 8.6% a lowering effect was distinct but incomplete, in 12.9% no satisfying effect occurred. After one hour average lowering of 1.5 to 1.9 degrees C was seen in nearly half of the cases, after three hours normal temperatures were found in all cases responding to Lonarid N at all. Lonarid N is acting promptly and normal body temperature is reached as expected. No complications of therapy were seen.

Acetaminophen↗

The German version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ).

We report the results of the cross-cultural adaptation and validation into the German language of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthritis (JIA). The Child Health Questionnaire (CHQ) is a generic health instrument designed to capture the physical and psychosocial well-being of children independently from the underlying disease. The German CHAQ was fully validated with 3 forward and 3 backward translations, while the CHQ has already been published and therefore it was revalidated. A total of 197 subjects were enrolled: 142 patients with JIA (5% systemic onset, 13% polyarticular onset, 8% extended oligoarticular subtype, and 74% persistent oligoarticular subtype) and 55 healthy children. The CHAQ clinically discriminated between healthy subjects and JIA patients, with the polyarticular and extended oligoarticular subtypes having a higher degree of disability, pain, and a lower overall well-being when compared to their healthy peers. Also the CHQ clinically discriminated between healthy subjects and JIA patients, with the polyarticular onset and extended oligoarticular subtypes having a lower physical and psychosocial well-being when compared to their healthy peers. In conclusion the German versions of the CHAQ-CHQ are reliable, and valid tools for the functional, physical and psychosocial assessment of children with JIA.

Adolescent↗

Lyme borreliosis in European children and adolescents.

Lyme borreliosis, a multi-system disease caused by infection with Borrelia burgdorferi, occurs most commonly in Europe and North America. This article reviews the vectors, epidemiology, clinical presentation, diagnosis, therapy, and pathogenesis of the disease, with particular regard to European children and adolescents.

Adolescent↗