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Biomedical subjects

F Diard

Publications and source records attributed to F Diard.

At least 55 records · Page 3Linked to original sources

Mucolipidosis II: correlation between radiological features and histopathology of the bones.

Twelve cases of Mucolipidosis II (I-cell disease) with a wide range of severity of skeletal involvement were studied. Pathological findings in two cases provided helpful information in understanding the radiographic features of dysostosis multiplex. Inhibition of the growth plate cartilage calcification and rickets-like lesions were observed in the metaphyses. Enhanced subperiosteal remodelling and paratrabecular fibrosis were also evident in the diaphyses. High levels of parathormone were found in one case. This finding supports the hypothesis that bone lesions may be secondary, at least in part, to damage in such viscera as the kidney and/or the liver and that they are mediated by vitamin D and parathormone.

Bone and Bones↗

[Subdural hematoma of the posterior fossa in a full-term newborn infant].

The authors report a case of subdural hematoma of the posterior fossa in a full-term neonate. The lack of specific symptoms is frequent. Diagnosis relies on CT scan and NMR data. In cases with neurologic involvement, good results depend on rapid neurosurgical treatment, in order to avoid sequelae.

Cranial Fossa, Posterior↗

[Radiologic change of cartilage of the pelvis and the upper end of the femur during growth. Application to the surveillance of scolioses].

We retrospectively studied the radiographic documents of seventy girls with bony age varying from nine to eighteen years old and divided in nine equal groups and seventy boys with bony age from ten to nineteen years old. We analyzed the AP pelvic X ray of each child focusing on cartilages and ossification centers of both pelvic bone and upper femoral extremity. The purpose of this study was to assess the dates of apparition and ossification of these ossification centers and the dates of fusion of cartilages. The iliac ossification center (epiphysaris nucleus ilii) appears lately at bony age of thirteen years and half for girls and fourteen years and half for boys. The triradiate cartilage closes the earliest from its medial to its lateral portion before the apparition of the iliac ossification center. This closing date corresponds to the beginning of growth acceleration. Therefore, the period of growth acceleration can be identified by an accurate analyse of the triradiate cartilage closure on a single AP pelvic X ray.

Adolescent↗

Midline omphalovesical anomalies in children: contribution of ultrasound imaging.

Based on reports of 9 surgically proven cases, the authors stress the contribution of high-resolution sonography in the work-up of omphalovesical midline anomalies in children. Sonography (US) proved useful, especially in disorders of urachal patency (cystic mass and sinus type of the malformation). In the cystic-type mass (3 cases), a midabdominal echogenic cystic mass was demonstrated. The echogenic content resulted from infectious complication. In the sinus type, an echogenic, thickened, tubular omphalovesical tract (8-15 mm) was visualized. This tubular configuration results from the normal omphalovesical anatomy, as can be demonstrated by high-resolution US. With infection, the fascia surrounding the urachal remnants seems to limit the infection. Differential diagnosis should include vesical duplications anomalies, dystrophic calcifications of the umbilical arteries remnants, and, in case of a solid mass, urachal carcinoma. Ultrasound should be part of the work-up of any suspected urachal or other midline anomaly.

Child, Preschool↗

[The association of a dysplastic kidney with a single vaginal ectopic ureter and a homolateral genital abnormality in a girl. Comments based on 3 case reports].

We recently treated one female infant and two young girls with coincidence of three anomalies: --hypoplastic ectopic kidney; --single vaginal ectopic ureter; --ipsilateral genital abnormality. Clinical presentation was lifelong wetting, "multicystic" kidney, urinary tract infection, or abdominal pain. The diagnostic studies include ultrasonography, excretory urography, cystography and vaginoscopic examination with retrograde catheterization, rarely radionuclide scanning. This study failed in two cases, with non visualization of the hypoplastic and dysplastic kidney, and diagnosis was done at laparotomy. Genital anomalies were unilateral hydrocolpos with uterus didelphys in one case, dilated or cystic Gärtner's duct in the other two. The anomaly may be caused by a maldevelopment of the wolffian and müllerian ducts in early fetal life, between 5 and 6 weeks of gestation. A review of the literature revealed only 6 similar instances in childhood. The combination of lifelong wetting, pelvic mass or pain in girl with "solitary" kidney on excretory urography and ultrasonography should alert to this syndrome. Meticulous search for the hypoplastic kidney, the genital abnormality and the ectopic ureteral orifice are keys to early accurate diagnosis and treatment.

Abnormalities, Multiple↗

[Magnetic resonance imaging in the diagnosis of an intraspinal arteriovenous malformation in a child].

A case of arteriovenous malformation of the spinal canal in a 8 year-old girl is reported. This child complained of night abdominal pain for several months, without diagnosis. Plain X-ray showed an enlargement of the lumbar spinal canal. Magnetic resonance imaging diagnosed a spinal vascular malformation, which was confirmed by angiography. Interest of MRI in such a case is emphasized.

Arteriovenous Malformations↗

[External epiphysiolysis with caput valga. Apropos of 2 cases].

External epiphysiolysis with valgus slip of the femoral epiphysis is rare. The authors report two such chronic cases, one unilateral and the other bilateral. This disorder complicates a coxa valga with a reversed cephalic growth plate, downward and externally. This coxa valga which appears constitutional is sometimes associated with an increase in femoral antetorsion. Treatment is the same as classical varus slip of the femoral epiphysis.

Adolescent↗

[Primary isolated vesico-ureteral reflux in children].

The advantages, complications or sequelae of surgical treatment of primary vesico-ureteral reflux in children are discussed in the light of 382 cases operated upon between 1971 and 1984. Changes in ideas on the fate of primary reflux and its consequences make it necessary to modify our therapeutic strategy, as shown by a study of our records and an exhaustive review of the literature. As a result, we suggest that reflux into a non-dilated ureter should not be operated, whereas reflux into a widely dilated ureter requires surgery. The operation should take place at an early stage in cases with severe renal lesions with pronounced radiological and biochemical alterations. In children with reflux of medium severity, the decision to operate or treat medically must rest on such criteria as age and severity, frequency and resistance of episodes of urinary infection, radiological and endoscopic data and signs of renal tissue functional damage.

Child↗

Intra-renal reflux: a new cause of medullary hyperechogenicity?

A 5-month-old infant with untreated severe urinary tract infection and bilateral vesico-ureteral reflux, had diffuse intrarenal reflux and hyperechogenicity of the medulla of two normal sized kidneys. We discuss the hyperechogenicity of the medulla in relationship to the intrarenal reflux.

Humans↗

[Pseudo-ureteroceles resulting from the impression of a loop of a megaureter with an ectopic subvesical orifice].

The authors report 3 rare cases of pseudo-ureteroceles corresponding to a vesical imprint of an ectopic extra-vesical megaureter. When an ectopic extra-vesical ureter follows a sharp juxta-vesical buckle, it can give a deep imprint on the bladder and look similar to an ureterocele. I.V.P. and U.S. can be as misleading since the appearance of this type of megaureter and ureterocele can be similar, and differential diagnosis can be difficult. Such situations are rare. In a ten years of pediatric urologic practice, the authors who have investigated 51 ureteroceles and 26 extravesical ectopic ureters, have only observed 3 children with this lesion. These 3 cases corresponded to two simple ureters, in a 3 year old boy and in a 2.5 year old girl, and one upper ureter of a complete duplex system in a neonate baby girl with antenatal discovery. The clinical, radiological, sonographical and endoscopic clues to the diagnosis are discussed and illustrated.

Child, Preschool↗

[Ovarian cyst in newborn infants: what attitude should we adopt? (apropos of 8 cases)].

With the advent of routine fetal ultrasonography, the frequency of prenatal diagnosis of ovarian cysts has considerably increased. Based upon a personal experience of 8 cases and a review of published series, the authors discuss the management of perinatal ovarian cysts. Before birth punction of the cyst under sonographic guidance or cesarean delivery may be considered in order to avoid the rupture during normal delivery. After birth, surgery should be performed in case or voluminous or complicated cyst or uncertain diagnosis. Homogenuos medium sized cysts or cysts with functional cytology should be followed by echography, before surgery being considered.

Female↗

[Acute chondrolysis on primary protrusio acetabuli in children].

Two cases of acute chondrolysis of the upper femoral epiphysis associated with protrusio acetabuli are reported in two girls respectively 13 and 12 Y.O. The disease was unilateral in one patient and bilateral in other. Acute chondrolysis is characterized by onset of pain, restricted movements of the hip and evolution to an hip ankylosis within a few months. As usual no evidence of inflammatory disease could be shown at biology or at pathology of synovial membrane or of femoral head. CT and MR studies proved to be contributive in the first case. It's the author's opinion that in these 2 cases, chondrolysis appears as a complication of preexistent Protrusio Acetabuli.

Acetabulum↗