[The pharmacologic profile of flutamide].
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Androgen Antagonists↗
Biomedical subjects
F Di Carlo
Publications and source records attributed to F Di Carlo.
[Correlation of histopathologic and immunohistochemical data (using the D5 antibody) and biochemical analysis in the study of estrogen receptors in breast carcinoma].
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Antibodies, Monoclonal↗
[Correlation of the biochemical and histochemical determination of hormone receptors in carcinoma of the breast with the age of the patient, stage and histologic type of the neoplasm].
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Adult↗
[Principles of the physiopathology of iron].
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Adult↗
[Effect of radio-opaque substances and local anesthetics on ciliary motility of the rhino-pharyngo-esophageal mucosa of the frog].
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Anesthetics, Local↗
Oxisuran metabolism in pigs.
The fate of oxisuran in the pig was studied with 14C-labeled drug to quantify its biotransformation and disposition. Despite interanimal differences, it was clear that the compound absorbed rapidly and biotransformed extensively to metabolites which were excreted principally in urine rather than in feces. Direct attacks upon oxisuran involved reduction to diastereo-isomeric oxisuran alcohol sulfoxides and oxidation to oxisuran sulfone. Subsequently, the oxisuran alcohol sulfoxides were reduced to a sulfide and oxidized to a sulfone. Phase II reactions appeared to be limited to sulfation of oxisuran alcohol sulfoxides and oxisuran alcohol sulfone. Pharmacokinetics were investigated for oxisuran and its metabolites.
Animals↗