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Biomedical subjects

F Desmons

Publications and source records attributed to F Desmons.

107 records · Page 6Linked to original sources

[Bazin's hydroa vacciniforme : photobiological and metabolic study in 3 cases, and discussion on etiopathogenicity (author's transl)].

The authors described three cases of Bazin's hydroa vacciniforme. Study of the history of the disease enables present nosological conceptions to be better understood. Diagnosis of hydroa vacciniforme is essentially clinical : appearance of the rash, periodicity and spontaneous improvement after puberty are characteristic. Hydroa vacciniforme has to be distinguished from porphyrias and polymorphous light sensitive eruptions. The etiology of this photodermatosis of child is unknown, but associated disturbances in tryptophan metabolism in some cases seem to be linked to a vitamin B6 deficiency.

Child, Preschool↗

[Apropos of the Mali syndrome].

The authors report two original cases of profuse pigmentation associated with proliferative lesions of the lower limbs, in patients with venous incompetence, suggestive if the syndrome described by Mali and al. in 1963. One case was in fact of Kaposi's disease associated with severe thrombocytopenia which was the cause of death, despite the use of Chloraminophene-Cortancyl. The other case was a woman with profuse pigmentation of the lower limbs associated with multiple disseminated lesions of allergic vasculitis, probably of drug origin. Suppression of the drug and rest led to a marked improvement in the lesions. Although very different from each other, both of these cases are suggestive of Mali's syndrome, but their treatment was totally opposite. The first case, a real vascular neoplasia, required the combination of antimitotic-steroid ; the second case, on the contrary, resolved with rest and a simple elastic bandage, like allcutaneous venous lesions, in particular Mali's syndrome.

Aged↗

[Apropos of the nature of vegetating pyodermatitis on chronic leg ulcers. Study of 7 cases].

The pyodermatitis proliferation around or on chronic leg ulcers derived from bone infection or of varicose origin is rare. The author, who has only seen 7 cases over the last ten years, stresses the importance of making an aetiological diagnosis which often has to be based on repeated histological examinations. Two clinically similar features have, in fact, very different natures and prognoses: one, pseudoepitheliomatous pyodermatitis (5 cases), is only a benign inflammatory reaction which is easily cured by simple curetage; the other, spiny cell epithlioma (2 cases), requires wide excision, or even amputation of the limb.

Adult↗

[Varicose eczema].

The term "varicose eczema", although made acceptable by its use, is ambiguous and misleading. It would prompt us to believe that varicose eczema is different from common dermatological eczema. There is no such difference, and it would be more correct to speak of eczema of the varicose patient. The development of eczema in the case of a varicose patient may:--either develop in the case of a varicose patient who does not normally suffer from eczematous dermatosis; in this case static dermatitis represents a point of local reference for an eczematous crisis triggered off by a general factor and finding there a zone of reduced resistance;--or develop in the case of a known habitual eczematic. In this case, venous stasis increases and maintains and eczema. In both cases no local dermatological treatment will be able to cure the eczema, which will develop into a critical condition often provoking the development of a leg ulcer, and will necessitate the suppression of the venous counter-current. To try and understand the pathological mechanism of "varicose eczema", we have to remember the rudiments of the physiology of the cutaneous barrier, familiar to dermatologists but less so to phlebologists, and also some elements of the physiopathology of venous insufficiency, and in particular the tissular elements following the pattern explained by Comel's Italian school, by the term "histo-angiological decompensation". The circulatory unit "arteries-capillaries-veins-lymphatic-vessels-tissues" form an ensemble which has to be taken into account, as any disorders in any one of these elements reacts on all the others. These elementary rudiments lead us to understand the importance of an integral aetiopathogenic picture of varicose eczema, and the importance of the multidisciplinary collaboration between phlebologists and dermatologists in order to treat this affection, the border-line of our two specialities.

Diagnosis, Differential↗

[Mucocutaneous angiomas in children. Must we still treat them?].

Muco-cutaneous angiomas are the most common vascular dysplasias in neonates born at term or especially prematurely. Rarely visible at birth, they appear during the first month of life, and always have a very great potential for development. Their extent is variable at onset, and their surface and volume, whatever their type, superficial, deep or mixed, both increase up to the age of 18 months and then diminish to be reabsorbed totally at the age of 3 to 4 years, leaving a zone of atrophic scarring with a cosmetic effect in proportion to the size of the lesion. The spontaneous cure of 90 % of these lesions is the argument used by clinicians who recommend therapeutic abstention. The conspicuous character of the scar, more marked in proportion to the size of the lesion, and the later involvement of organs subjacent to the angioma such as the eye, nasal cartilage, and bones, are the reasons which lead us instead to recommend the routine treatment of every tuberous angioma, provided certainly that such treatment is appropriate to the clinical variety ; treatment should be carried out as soon as possible after birth, and should not represent a risk disproportionate to the innocence of the lesion.

Angiokeratoma↗