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Biomedical subjects

F Desmons

Publications and source records attributed to F Desmons.

At least 37 records · Page 2Linked to original sources
PubMed1977

Multiple clear-cell acanthoma (Degos): histochemical and ultrastructural study of two cases.

Two patients with clear-cell acanthoma with multiple lesions are reported; histologic and histochemical findings are similar to previous descriptions. The ultrastructural study confirms the overload of glycogen in keratinocytes, associated with an increase of mitochondria and nuclear deformations. The abundance of Langerhans' cells is emphasized. Extrusion of glycogen by keratinocytes and its phagocytosis by Langerhans' cells is suggested.

Aged↗
PubMed1977

[Study of the role of Candida albicans infection in different infant conditions including a diaper rash (64 cases)].

The pathogenic role of Candida albicans has been determined by performing: skin scrapings, mouth swabs, faecal specimens and serology from 64 infants and very young children affected with different conditions including a napkin dermatitis, divided into 4 groups. 1) 7 patients affected with true or presumed candidiasis, 2) 53 patients with different manifestations of diaper dermatitis, 3) 3 patients with papulo-erosive dermatitis of the diaper area, 4) 1 congenital ichthosiform erythrodermia. Candida albicans is the only responsible agent of the granulomatous candidiasis, it is constant but appeared lately in acropathia enteropathica. It is one of the major agents of the trichophytoid dermatitis (2 cases out of 4 cases). Candida albicans has been recovered from the skin of 33 infants out of 53 patients affected with all types of napkin eruption (62 p. 100) and from faecal specimens of 43 patients (81 p. 100). Though Candida albicans has often been considered as an opportunistic organism, even in infants, this percentage is greatly higher than that of the normal infant that is about 4p. 100, and consequently has a real pathogenic value. Species of yeasts different from Candida albicans have been recovered from faecal specimens of 3 infants affected with papulo-erosive dermatitis of the napkin area: parapsilosis, macedoniensis, deformans which are not generally considered as pathogenic agents. Serology is positive only in 3 infants or young children affected with a real chronical candidosis: 1 granulomatous candidosis, 1 acropathia enteropathia, 1 erythrodermia, the faecal specimen of whom contained a great nomber of Candida albicans.

Candida albicans↗
PubMed1977

HLA antigens and atopic dermatitis.

The frequency of HLA antigens was determined in 27 unrelated children and 44 of their parents, compared to 326 healthy controls. HLA-BW35 frequency is significantly increased in the patients (37 instead of 11.6%; Pc less than 0.01) and in the parents (34 instead of 11.6%; Pc less than 0.05). However HLA segregation was not disturbed in 23 families with 33 patients and 24 healthy siblings. These data confirm the hereditary character of atopy but does not allow the exclusion of the hypothesis of a linkage between a HLA-B gene and an Ir gene conditioning abnormal humoral response to several allergens.

Asthma↗
PubMed1977

[Congenital nodular fibromatosis: report of six personal cases (author's transl)].

Six personal cases of nodular congenital fibromatosis are reported: one fibromatosis colli, two fibromas of the fingers one multiple fibromas of the toes and sole associated with osteoporosis and underlying bone lacunes, one recurrent plantar fibromatosis, one disseminated fibromatosis with multiple bone lesions. Such varieties of fibromatosis are very uncommon. Few are isolated such as fibromatosis colli or the fibroma of the fingers. The prognosis is generally good except for the generalized multinodular form which associates a very large visceral involvement. Aetiology is completely unknown. Only few arguments are in favour of an hereditary dominant autosomal transmission of the diffuse multinodular form.

Adolescent↗