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Biomedical subjects

F Demard

Publications and source records attributed to F Demard.

At least 109 records · Page 6Linked to original sources
PubMed1984

[Pectoralis major musculocutaneous flap after oncologic excision of the buccal cavity and oropharynx].

A musculocutaneous flap from pectoralis major was used for reconstruction after widespread excision for cancer of the oral cavity and oropharynx in 54 cases, the method of choice being transposition as islets. Necrosis in 6 cases (11%), was partial in 5 patients and was limited to the skin layer only. The advantages of the musculocutaneous flap from pectoralis major when compared with other reconstructive procedures, particularly deltopectoral and temporofrontal flaps, are discussed.

Female↗
PubMed1984

[Endoscopy of the maxillary sinus. Diagnostic and therapeutic value in chronic sinusitis].

Sinus endoscopy is now well established as an essential exploratory procedure for the study of rhinosinus affections. By direct endocavitary observation, after identification and evacuation of possible secretions, it enables the anatomical and functional state of the mucosa to be studied, as well as that of the ostial region. For the maxillary sinus, the most easily accessible, direct endoscopic examination has become indispensable for a precise diagnosis of any chronic inflammatory or infections process, when associated with cyto-bacteriologic, colorimetric, manometric and possibly histologic investigations, completing clinical and radiologic findings when necessary. Endoscopy can also often act as the primary therapeutic gesture, its evacuating and aerating properties relieving ostial dyspermeability, the principal cause of chronic maxillary sinusitis. Diagnostic and therapeutic features in this particularly frequent affection are discussed with respect to the use of endoscopy.

Adolescent↗
PubMed1983

[Primary chemotherapy combining vincristine, bleomycin, methotrexate and cisplatin systemically or intra-arterially in cancers of the upper respiratory and digestive tracts].

85 patients with tumors of the upper respiratory/digestive tract were treated during an initial stage by polychemotherapy associating Vincristine, Bleomycin, Methotrexate and Cis-platinum. Administration was either by a systemic route (two cycles at a ten-day interval) or by a combination intra-arterial and intra-venous route (18-day protocol). Complete regression or regression greater than 50% of tumor volume was observed with the combination route in 76.5% of cases versus only 56.5% with use of the systemic route. In contrast, the percentage of lymph node regressions was less than 30%. No serious toxicity was observed and the classical treatment by radiotherapy for curative purposes (51 cases) or by surgery alone or associated with postoperative irradiation (30 cases) was then able to be completed without any complications linked to this initial treatment. The probability of survival, evaluated by the Log Rank Test, was significantly longer for patients who showed a positive response to initial chemotherapy.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1983

[Echography and parotid tumors].

Morphological criteria obtained from ultrasonic exploration of 82 parotid tumors were compared with histological findings. Precise determination was possible of the size of the tumor, its cystic or solid nature, and the pre-operative evaluation of its benign or malignant nature. In spite of certain deficiencies, the safety, rapidity of execution, and reliability of ultrasonography make it a complementary investigation of choice for all isolated nodular lesions in the parotid region before surgical exploration, which remains indispensable.

Adolescent↗
PubMed1982

Echographic aspects of thyroid and parotid localizations in non-Hodgkin lymphomas.

The authors present four observations of rare localizations of non-Hodgkin lymphomas (3 cases of lymphoma of the thyroid, 1 case of lymphoma of the parotid), all of which were studied by echography. In two of the thyroid localizations, the echographic pattern was identical to that observed for nodes in non-Hodgkin lymphomas, and thus differs from that of cysts and necrotized or cystic tumors. In the one case of secondary lymphoma of the thyroid, accompanied by diffuse enlargement of the gland but no histological proof, echography revealed only diffuse enlargement, without any anomaly in the echostructure. In the one case of lymphoma of the parotid, the echographic image was similar to that of a lymphomatous node, but it cannot be formally differentiated from the structure which can be observed for a mixed tumor or a cystic lymphangioma.

Adult↗
PubMed1982

[Carcino-embryonic antigen assay in cancer of the upper respiratory and digestive tracts].

Radioimmunological assay of carcino-embryonic antigen (CEA) was performed in 238 patients with cancer of the upper respiratory and digestive tracts after a minimum follow-up period of 3 years. Secretion of CEA was observed in only 1 out of 3 cases, levels, always being low and only slightly influenced by the localization or size of the tumor, and the condition of the lymph nodes. Initial levels are of no prognostic significance. The appearance of high levels during the course of the disease corresponds to shorter survival, but as it does not precede clinical evidence of recurrence or metastases this assay cannot play a role as a tumor marker.

Carcinoembryonic Antigen↗
PubMed1980

[Ultrasonic findings of parotid tumours in 40 patients].

Ultrasonic findings of 40 parotid tumours are presented in this paper. After a technical description proceeding they show the ultrasonic pattern of the three main types of parotid tumours: mixed tumours, adenolymphomas and carcinomas. The differential diagnosis between malignancy and non malignancy is carried out in 87,5% of cases. This rate of success is, according to literature data, similar to that of sialography. Since it is non invasive, the authors recommend sonography in the assessment of parotid tumours, rather than sialography.

Adenolymphoma↗
PubMed1979

[Repair after circular pharyngo-laryngectomy with deltopectoral flap (author's transl)].

Eleven patients with advanced tumors of eso-pharyngeal area were treated by circular eso-pharyngo-laryngectomy with repair of pharyngo-esophageal continuity by deltopectoral flap (V. Y. Bakamjian). Surgical procedures are described and results presented. Advantages and failures, compared with others techniques, have allowed us to recommend the use of deltopectoral flap, especially when the tumor remains located in hypopharyngeal region and doesn't exceed one cm below the eso-pharyngeal ring.

Humans↗