[Hereditary ichthyosis].
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Biomedical subjects
Publications and source records attributed to F Deleixhe-Mauhin.
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Certain features of the skin of patients undergoing chronic haemodialysis suggest an ageing process. Seventy-two haemodialysed patients were studied by a non-invasive technique using the Cutometer SM 474 to determine biomechanical properties of the skin. Patients undergoing chronic haemodialysis showed some impairment of changes in viscous properties of skin similar to chronological age, while specific changes directly related to elasticity were minimal.
Xerosis and hydration of the stratum corneum were evaluated in 60 hemodialyzed patients. Xerosis and a low capacitance of the stratum corneum were evidenced in more than 80% of the patients. Pruritus was present in two third of the subjects. We failed to disclose any significant relationship between severity of these three parameters.
BACKGROUND: In patients undergoing long-term hemodialysis, a peculiar hyperpigmentation develops, the intensity of which may or may not be related to the duration of treatment and use of erythropoietin. OBJECTIVE: Our purpose was to conduct a comparative cross-sectional study of white patients with distinct diseases that modify their skin color. METHODS: A reflected-light colorimeter was used to compare the color of the forehead and forearms of 61 white patients receiving hemodialysis with that of matched controls and of patients with anemia or icterus. RESULTS: Significant differences were found in both reflectance and chromaticity between these groups of patients. Duration of hemodialysis and use of erythropoietin did not significantly influence the colorimetric measurements. CONCLUSION: The use of a color-reflectance meter allows precise evaluation of subtle changes in skin color and may be used to monitor several diseases.
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In a series of fibrotic and sclerotic diseases including scars, keloids, fibromas, scleroderma and lichen sclerosus et atrophicus, we found modifications in the dendrocyte population. Dendrocytes were numerous in fibrotic diseases associated with little deposits of collagen. Conversely, they were almost absent in sclerotic diseases when the lay-down of collagen was prominent. We hypothesize that dendrocytes, by their content in factor XIIIa, may limit the accumulation of collagen in the skin.
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