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Biomedical subjects

F D Moore

Publications and source records attributed to F D Moore.

At least 145 records · Page 8Linked to original sources
PubMed1976

Assessment of serial carcinoembryonic antigen (CEA) assays in postoperative detection of recurrent colorectal cancer.

Monthly serial postoperative CEA determinations, three-monthly system review plus physical examination, and a battery of six-monthly laboratory and radiologic tests were compared in order to evaluate each in detection of recurrent colorectal cancer. Twelve of the 33 patients studied prospectively developed recurrent disease. In this study CEA was found not to be a substitute for careful clinical follow-up, but if used in a serial manner it was a useful adjunct for detection of early recurrent cancer, especially intra-hepatic and retroperitoneal disease recurring in patients with elevated pretreatment CEA levels. The other laboratory and radiologic tests employed were often useful to confirm progressing disease, but they did not reveal any first evidence of recurrent disease.

Carcinoembryonic Antigen↗
PubMed1976

La maladie post-operatoire: Is there order in variety? The six stimulus-response sequences.

The search for a unifying concept in all post-traumatic metabolism, symbolized by the phrase "la maladie post-operatoire" has been a fruitful one, not so much because of success, as through its very failure. There is such variety in convalescent patterns that it has made it essential for students of this subject to look more closely at the nature of the stimulus response patterns and bring sharply into focus those recurring phenomena whose mixture together determines the final clinical result. In this brief introductory paper six groups of stimulus-response patterns have been identified and analyzed. The clinician needs an understanding of these patterns in everything that he does for the patient, both within the operating room and on the ward. The student of surgery must make an effort to differentiate amongst the six stimulus-response patterns. If he fails to do so he will be analyzing all surgical recovery as falling under a single sequence, an error that has been all too frequent in the literature. There may be other stimulus response patterns of greater importance which will be added to the list presented here, as research in the coming decades increases our understanding of convalescent biology. This presentation will serve as an introduction to the other papers gathered in this symposium by Dr. Clowes, all of which cast further important light on the details of the stimulus and response in surgical metabolism.

Anaerobiosis↗
PubMed1976

Manpower goals in American surgery. Implications for residency training. Future surgical manpower in the framework of total United States physicians.

Constraints on manpower are intrinsic in the establishment of standards of excellence. When such constraints are exerted by individual Boards, Societies, Colleges or Academies they should act to improve the quality of care; their weakness lies in their lack of control over non-members, or those who have failed to pass the examinations. Such manpower constraints become specific objectives or goals when the number of accredited specialists is specifically related to the size of the population served. Any such manpower planning must recognize the many uncertainties in the future of American medicine, and maintain wide elasticity in the planning process. Social and economic pressures render the consideration of specific manpower goals essential at this time. Data from the national surgical study (SOSSUS) make it possible to consider such goals. Manpower objectives for surgery or any other branch of medicine should be considered as a part of the total medical manpower outlook for the United States. Pressures to reduce the number of surgeons entering practice are notable at this time. These should be evaluated against other pressures to maintain or increase the number of hospital-based specialists in all fields as the total number of practitioners undergoes a major expansion over the next 25 years, and the pressure for specialty care is thereby increased. A reasonable balance between these two pressures would be a manpower goal for surgery that allowed a modest growth rate over the next 25-50 years. An example of such is the goal of limiting surgical practitioner growth to a 1% increase in the ratio to population, every 5 years. This would be in sharp contrast to the continuous explosive growth of numbers of surgeons, since World War II.

Certification↗
PubMed1975

Epidemiology of burns. The burn-prone patient.

Predisposition to burning was identified by history, by conversation with the family, or by physical examination. Factors that decreased the patient's ability to respond appropriately were considered as predisposing. A consecutive series of 155 hospitalized, burned, adult patients was reviewed. Approximately 50 per cent of the entire series showed predisposition to burning; among the more severe burns, this fraction was 57 percent. Among women, predisposition was more prominent in all categories than among men. Among women, those predisposed to burning had larger burns and a greater likelihood of dying. Alcoholism led the list of predisposing factors, with senility, psychiatric disorders, and neurological disease following in order. The patient's own home was usually the site of the burn in those predisposed, with the initial ignition being in the patient's hair or clothing, the mattress, bedclothes, or an overstuffed chair. All of the burns occurring in hospital or mental institution patients were among those predisposed to burning.

Accident Prevention↗