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Biomedical subjects

F D Loop

Publications and source records attributed to F D Loop.

At least 181 records · Page 10Linked to original sources
PubMed1981

Late clinical and arteriographic results in 500 coronary artery reoperations.

The incidence of coronary artery reoperations averaged 2.7% from 1967 through 1979. In a mean interval of 51 months between operations, three-vessel disease increased from 24% to 63%, and 31% of these 500 consecutive patients lost previously normal left ventricular function. Three angiographic indication groups were identified: (1) progressive coronary atherosclerosis, 247 (51%); (2) graft failure, 147 (29%); and (3) a combination of progressive coronary atherosclerosis and graft failure, 96 (19%). Angina recurred earlier in patient with graft failure, mean 17 months compared with a mean of 37 months for the other groups. Twenty (4%) operative deaths occurred. The series is divided into 387 patients operated upon under normothermic anoxic arrest and 113 with systemic hypothermia and cold cardioplegia. In the cardioplegia group, perioperative myocardial infarction was 2.7% in comparison with 7.8% for patients with anoxic arrest (p = 0.055). The number of grafts per patient increased from 1.0 to 1.9 and blood usage decreased from 11 units to 2.7 units. After a mean follow-up of 42 months, angina was relieved or improved in 86%. Recatheterization of 104 patients after a mean interval of 19 months showed a 79% vein graft patency rate and a 97% mammary artery graft patency rate. Grafting performed for graft failure (47) yielded an 85% patency rate. Actuarial 5 year survival was 87.4% for those with progressive atherosclerosis, 89.4% for patients with graft failure, and 91.5% for the combined indication group. Clinical improvement, graft patency, and long-term survival are nearly equal among the indication groups. Palliation derived from these reoperations approaches that achieved after primary revascularization.

Adult↗
PubMed1980

Late survival following use of intraaortic balloon pump in revascularization operations.

The early and late results of intraaortic balloon pump (IABP) support in 197 patients with pure myocardial revascularization were analyzed. Group I, 61 patients, had IABP support initiated preoperatively; Group II, 99 patients, had IABP support in the operating room because of inability to be weaned from bypass; and Group III, 37 patients, had support instituted for persistent low cardiac output state in the postoperative period. The early results showed that 73% were discharged from the hospital and that delayed use of the IABP was associated with a high mortality and high rate of perioperative myocardial infarction. When the results between men and women were compared, no statistical difference was noted. After a mean follow-up of 18 months, there were 9 late deaths. Three were due to noncardiac causes. The two-year cardiac actuarial survival for the hospital survivors was 96% and all three groups had uniformly good symptomatic relief. After hospital discharge, the late results of patients who required use of the IABP in conjunction with pure myocardial revascularization were the same as for patients who did not require IABP support.

Assisted Circulation↗
PubMed1980

Initial clinical experience with a new temporary left ventricular assist device.

A new, simple left ventricular assist system has been developed and its use in experimental animals has been evaluated. The system achieves ventricular drainage by a transaortic valve cannula and utilizes a new centrifugal pump; the blood access is unique in requiring only a simple end-to-side synthetic graft anastomosis to the ascending aorta. Adequate pulsatility is obtained by concomitant use of an intraaortic balloon pump. This case report documents our initial clinical experience with this system in a postoperative patient with profound left ventricular failure unresponsive to all usual treatment. There was temporary recovery of left ventricular function upon decannulation after five and a half days of assist pumping. Despite the eventual death of the patient, the system functioned adequately, suggesting that it has good potential for use in a small, selected group of patients.

Assisted Circulation↗
PubMed1980

Isolated left anterior descending coronary atherosclerosis: long-term comparison of internal mammary artery and venous autografts.

A consecutive series of 100 patients receiving left internal mammary artery grafts and a consecutive series of 100 patients receiving saphenous vein grafts as treatment of isolated left anterior descending coronary artery stenosis were reviewed to determine survival, graft patency, disease progression and New York Heart Association functional class. The mean follow-up was 67 months, and the mean catheterization interval was 20 months. Recommendations for revascularization can be made selectively to patients with critical isolated left anterior descending stenoses who have limiting symptoms and large areas of viable myocardium at risk.

Angina Pectoris↗