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Biomedical subjects

F Coursange

Publications and source records attributed to F Coursange.

14 recordsLinked to original sources

[Effect of the rate of injection of propofol on blood pressure and heart rate].

This work aimed to confirm the lack of haemodynamic effect due to the speed of injecting propofol during induction of anaesthesia. Thirty young unpremedicated ASA I patients were studied. They were randomly assigned to three groups. Induction was carried out with a single dose of 2.5 mg X kg-1 propofol, at three different speeds of injection (15, 30 and 45 s for groups 1, 2 and 3 respectively). Heart rate and systolic and diastolic blood pressures were recorded before injection and every 45 s after the end of the injection of propofol with a Doppler recorder. Statistical analysis of data was performed with Tukey's test. Systolic and diastolic arterial pressures decreased in all cases. There was an increase in heart rate which was not statistically different from control. There were no statistically significant differences between the median falls in blood pressure between groups.

Adult↗

[Rupture of an intracranial aneurysm after spinal anesthesia].

A case is reported of an intracranial aneurysm which ruptured after spinal anaesthesia. A 36-year-old man underwent several locoregional anaesthesias for the surgical treatment of an infected lower limb fracture (8 epidural blocks and 1 spinal anaesthesia). After a further spinal anaesthesia, he suffered violent headaches, a meningeal syndrome, restlessness, left hemiplegia and coma. The relationship between such an accident and the anesthesia is discussed in the light of similar cases previously published.

Adult↗

[A deep skin burn caused by the local application of a traditional oily ointment of Senegal (Carapa procera)].

Many traditional ointments are utilized in Senegal because of their local effects. We report the case of a new born girl deeply burned by the application of "Touloucouna" (Carapa Procera) on her skin. The berries of the tree contain cyclic terpens (Meliacine) well known for inducing inflammation by contact with the skin. They are most likely responsible for that burn until now, such injuries have never been described with Touloucouna.

Antiviral Agents↗

[Urinary tract infection and surgical disorders of the lower urinary tract].

Infection is a constant concern during perioperative period. Bacteremia occur during intervention and immediate postoperative period. They are the risk of acute complications, mainly septic shock with a high mortality rate. Escherichia coli is the germ most often found, then Enterococcus and other gram-negative germs. Diagnosis of an urinary infection is made difficult because the presence of a vesical catheter; so, 10(3) bacteria per ml. have to be considered as pathological. Two therapeutic behaviours can be considered in practice: suitable antibiotherapy in obvious infections, but sterilization of urines must not delay surgical intervention, short-time peri-operative prophylaxis cephalosporins of the 2nd or 3rd generation are most often utilized. Overseas, trimethoprim associated with sulfamides can be administrated per os every 2 hours before surgical intervention, at the time of anesthesia for example.

Anti-Infective Agents, Urinary↗

[Malnutrition].

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Adult↗

[A case of ureteral bilharziasis followed for 22 years].

The authors report on one case of urinary schistosomiasis monitored for 22 years. It illustrated the problems posed by the "bilharzial uretero-hydronephrosis". They analyse the different therapy problems which have to have been successively solved: Low double ureteral stenosis. The difficulty to be certain of such a stenosis is recalled. The possibility of a reflux or an ureteral atony must be eliminated. True stenosis must be operated without delay; Kidney cancer revealed 20 years later through chronic renal failure by vesico-ureteric reflux caused by the first surgical intervention (latero-lateral vesico-ureteric anastomosis); Iatrogenic vesico-ureteral reflux, treated by uretero-vesical implantation on "psoic" bladder with anti-reflux submucous path. The future of such a chronic renal failure is linked to the capability of the remaining ureter to ensure an acceptable passage of urine, and to the rehabilitation possibility of the kidney. Finally, the authors recalled the difficult therapeutic indications in case of ureteral attack due to bilharziosis.

Follow-Up Studies↗

[Valium-Acupan combination--its value at an isolated health center].

Twelve anaesthesias of the diazo-analgesia type have been carried out using a combination of two non depressive analgesics: a narcotic one and a powerful central one. These interventions are classified; used technique is described and results are commented on. Indications are not too painful quick surgical acts performed on patients with an empty stomach.

Anesthetics↗