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Biomedical subjects

F Cimino

Publications and source records attributed to F Cimino.

81 records · Page 5Linked to original sources
PubMedDate not supplied

[Treatment of local recurrences of rectal cancer].

In this work we report the results of 27 patients who underwent a second surgical operation for local disease recurrence after colorectal surgery for cancer. We describe the different intervention we performed and for everyone of them we analyze intraoperative mortality and morbidity, long term survival and quality of life related.

Humans↗
PubMedDate not supplied

[Multiple organ resection in advanced gastric carcinoma: experience of 7 years].

In this work we report our experience on multiorgan resections (MOR) for local advanced gastric cancer. From 1998 to 2004 in our Department 79 patient underwent total or partial resection of stomach associated with removal of various other organs. The results we report come from the evaluation of perioperative mortality and morbidity rates and further analysis of median survival time and quality of residual life. In conclusion, we affirm the utility of major surgery in advanced gastric cancer only in conditions that guarantee an acceptable rate of major complications.

Adult↗
PubMedDate not supplied

[Health education through sports. Proposal for an intervention in the formative years].

The authors present the program: "Physical fitness and health education", direct to childhood of secondary school. The goal is to encourage physical activity and behaviors linked with exercise (caloric intakes and weight control, no smoking ...) to improve health and fitness. The accomplishments of the program need collaboration between physicians and gym teachers to determine methods of realizations and verifications of the program. The educational program has been based on the operative pattern introduced by Guilbert. It is developed through four stages: 1) Definition of pedagogical objectives. The authors point three intermediate objectives a) acquisition of theoretical and practical elements characterizing training exercises wealthy for growth and health; acquisition of the right attitudes not be lose the aforesaid educational contents. b) acquisition of theoretical and practical elements characterizing a diet wealthy for growth and efficiency in sports; acquisition of the right attitudes not be lose the aforesaid educational contents. c) acquisition of theoretical and practical elements for a correct way of life allowing growth and efficiency in sports; acquisition of the right attitudes not be lost the aforesaid educational contents. 2) Definition of methods of verification. The authors point out the following: a) written and oral test, questionnaires for the valuation of the "know" level b) practical tests for valuation of the "know how to do" level c) reports from the teachers of valuation of the "know how to be" level. 3) Organization and realization of the program. The authors point out educational contents to get the three intermediate objectives, together with the times for realization of the program. The fixed program is introduced to the young people at the beginning of secondary school in physical education periods all over the three years of the first grade course. 4) The authors point out the moments of verifications: beginning and end of each or the three years of course.

Attitude to Health↗
PubMedDate not supplied

A mouse tRNA pseudogene derived from a tRNA(Trp) coding sequence.

The identification and characterization of a mouse tRNA(Trp) pseudogene is reported. A synthetic oligonucleotide (31 mer), identical with the 3' half of a tRNA(Trp), was used to examine three mouse lambda clones that are known to contain clusters of tRNA genes. A fragment of one of these lambda clones strongly hybridizes to the oligonucleotide; the sequence of this region shows the presence of a gene significantly homologous to the chick tRNA(Trp). However two point mutations and a three base deletion prevent the folding of a possible transcript of this gene. The presence of a conserved promoter sequence for RNA polymerase III, that should allow the transcription of this gene, does not ensure the transcription of the gene, at least in our in vitro system.

Animals↗
PubMedDate not supplied

Ferritin H and L mRNAs in human neoplastic tissues.

The typical tissue isoferritin pattern varies during neoplastic transformation, usually shifting toward a more acidic profile. To investigate the molecular basis of this phenomenon, we have analyzed the steady-state levels of the H and L mRNAs in several neoplastic tissues. By using specific probes for the two ferritin subunits, we have found, in three different adenocarcinomas and in a case of Hodgkin lymphoma, a two- to four-fold increase of the H and L mRNA levels compared to those found in normal human liver.

Adenocarcinoma↗